Brain endothelial TAK1 and NEMO safeguard the neurovascular unit (Q36080694)

12 August 2017

Brain endothelial TAK1 and NEMO safeguard the neurovascular unit (English)

1 reference

12 August 2017

0 references

Marc Schmidt-Supprian

19

Marc Schmidt-Supprian

0 references

Markus Schwaninger

Markus Schwaninger

26

0 references

Manolis Pasparakis

Manolis Pasparakis

21

0 references

Dirk Rades

17

Dirk Rades

1 reference

12 August 2017

18

Lydia M Sorokin

1 reference

12 August 2017

15

Eva Korpos

1 reference

12 August 2017

Dirk A Ridder

1

1 reference

12 August 2017

Jan Wenzel

2

1 reference

12 August 2017

Kristin Müller

3

1 reference

12 August 2017

Kathrin Töllner

4

1 reference

12 August 2017

Xin-Kang Tong

5

1 reference

12 August 2017

Julian C Assmann

6

1 reference

12 August 2017

Stijn Stroobants

7

1 reference

12 August 2017

Tobias Weber

8

1 reference

12 August 2017

Cristina Niturad

9

1 reference

12 August 2017

Lisanne Fischer

10

1 reference

12 August 2017

Beate Lembrich

11

1 reference

12 August 2017

Hartwig Wolburg

12

1 reference

12 August 2017

Marilyn Grand'Maison

13

1 reference

12 August 2017

Panayiota Papadopoulos

14

1 reference

12 August 2017

Francois Truchetet

16

1 reference

12 August 2017

Marc Schmidt-Supprian

19

1 reference

12 August 2017

Barry J Bedell

20

1 reference

12 August 2017

Detlef Balschun

22

1 reference

12 August 2017

Rudi D'Hooge

23

1 reference

12 August 2017

Wolfgang Löscher

24

1 reference

12 August 2017

Edith Hamel

25

1 reference

12 August 2017

language of work or name

English

0 references

publication date

7 September 2015

1 reference

Journal of Experimental Medicine

12 August 2017

1 reference

12 August 2017

212

1 reference

12 August 2017

1529-1549

1 reference

12 August 2017

10

1 reference

describes a project that uses

12 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4577837/fullTextXML

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A new type of microglia gene targeting shows TAK1 to be pivotal in CNS autoimmune inflammation

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2 October 2017

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2 October 2017

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TAK1 kinase signaling regulates embryonic angiogenesis by modulating endothelial cell survival and migration

2 October 2017

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NEMO inhibits programmed necrosis in an NFκB-independent manner by restraining RIP1.

2 October 2017

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Targeting of TAK1 in inflammatory disorders and cancer

2 October 2017

1 reference

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Apolipoprotein E controls cerebrovascular integrity via cyclophilin A.

2 October 2017

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Neurological findings in incontinentia pigmenti; a review

2 October 2017

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Elementary Ca2+ signals through endothelial TRPV4 channels regulate vascular function.

2 October 2017

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TAK1 in brain endothelial cells mediates fever and lethargy

2 October 2017

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Occludin: one protein, many forms

2 October 2017

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Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders

2 October 2017

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TNFAIP3 maintains intestinal barrier function and supports epithelial cell tight junctions

2 October 2017

1 reference

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C5a/CD88 signaling alters blood-brain barrier integrity in lupus through nuclear factor-κB

2 October 2017

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Adenosine receptor signaling modulates permeability of the blood-brain barrier.

2 October 2017

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2 October 2017

1 reference

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cIAP1 and TAK1 protect cells from TNF-induced necrosis by preventing RIP1/RIP3-dependent reactive oxygen species production

2 October 2017

1 reference

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Cerebral microcirculation is impaired during sepsis: an experimental study

2 October 2017

1 reference

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2 October 2017

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A review of string vessels or collapsed, empty basement membrane tubes

2 October 2017

1 reference

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Early infantile manifestations of incontinentia pigmenti mimicking acute encephalopathy

2 October 2017

1 reference

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A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

2 October 2017

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2 October 2017

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Lymphocytic choriomeningitis virus-induced mortality in mice is triggered by edema and brain herniation

2 October 2017

1 reference

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Molecular signatures of disease brain endothelia provide new sites for CNS-directed enzyme therapy

2 October 2017

1 reference

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Plasmodium falciparum-infected erythrocytes induce NF-kappaB regulated inflammatory pathways in human cerebral endothelium

2 October 2017

1 reference

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Divergent roles of endothelial NF-kappaB in multiple organ injury and bacterial clearance in mouse models of sepsis

2 October 2017

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The blood-brain barrier in health and chronic neurodegenerative disorders

2 October 2017

1 reference

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Extensive cerebral infarction in the newborn due to incontinentia pigmenti

2 October 2017

1 reference

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Lethal silver-haired bat rabies virus infection can be prevented by opening the blood-brain barrier

2 October 2017

1 reference

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TGF-beta receptor-mediated albumin uptake into astrocytes is involved in neocortical epileptogenesis

2 October 2017

1 reference

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NF-kappaB regulation of endothelial cell function during LPS-induced toxemia and cancer

2 October 2017

1 reference

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Neurovascular coupling in the normal brain and in hypertension, stroke, and Alzheimer disease

2 October 2017

1 reference

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Lasting blood-brain barrier disruption induces epileptic focus in the rat somatosensory cortex.

2 October 2017

1 reference

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The skin is not the predominant problem in incontinentia pigmenti

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577837

Hypoxia-induced vascular endothelial growth factor expression causes vascular leakage in the brain

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577837

Complex phenotype of mice lacking occludin, a component of tight junction strands.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577837

Female mice heterozygous for IKK gamma/NEMO deficiencies develop a dermatopathy similar to the human X-linked disorder incontinentia pigmenti

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577837

Disruption of the glucocorticoid receptor gene in the nervous system results in reduced anxiety

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577837

TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling

2 October 2017

1 reference

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A nonparametric method for automatic correction of intensity nonuniformity in MRI data

2 October 2017

1 reference

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Developmental regulation of the laminin alpha5 chain suggests a role in epithelial and endothelial cell maturation

2 October 2017

1 reference

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A cre-transgenic mouse strain for the ubiquitous deletion of loxP-flanked gene segments including deletion in germ cells

2 October 2017

1 reference

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Automatic 3D intersubject registration of MR volumetric data in standardized Talairach space

2 October 2017

1 reference

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Mutations in the gene encoding PDGF-B cause brain calcifications in humans and mice

2 October 2017

1 reference

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IL-1beta regulates blood-brain barrier permeability via reactivation of the hypoxia-angiogenesis program.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577837

Occludin as a possible determinant of tight junction permeability in endothelial cells

11 July 2018

1 reference

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Computed tomographic demonstration of brain changes in incontinentia pigmenti

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577837

Early cortical thickness changes predict β-amyloid deposition in a mouse model of Alzheimer's disease

11 July 2018

1 reference

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Cortical atrophy and hypoperfusion in a transgenic mouse model of Alzheimer's disease

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577837

Conditional targeting of tumor necrosis factor receptor-associated factor 6 reveals opposing functions of Toll-like receptor signaling in endothelial and myeloid cells in a mouse model of atherosclerosis.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577837

Age-dependent rescue by simvastatin of Alzheimer's disease cerebrovascular and memory deficits.

23 September 2018

1 reference

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NF-κB activity in perinatal brain during infectious and hypoxic-ischemic insults revealed by a reporter mouse.

23 September 2018

1 reference

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Hippocampal tauopathy in tau transgenic mice coincides with impaired hippocampus-dependent learning and memory, and attenuated late-phase long-term depression of synaptic transmission.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577837

Simvastatin improves cerebrovascular function and counters soluble amyloid-beta, inflammation and oxidative stress in aged APP mice.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577837

Endothelial basement membrane laminin alpha5 selectively inhibits T lymphocyte extravasation into the brain

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577837

GFP-p65 knock-in mice as a tool to study NF-kappaB dynamics in vivo.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577837

Endothelial cell-specific NF-kappaB inhibition protects mice from atherosclerosis

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577837

Longitudinal neuroanatomical changes determined by deformation-based morphometry in a mouse model of Alzheimer's disease.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577837

TWEAK-Fn14 pathway inhibition protects the integrity of the neurovascular unit during cerebral ischemia.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577837

Vascular remodeling versus amyloid beta-induced oxidative stress in the cerebrovascular dysfunctions associated with Alzheimer's disease.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577837

Specific modulation of airway epithelial tight junctions by apical application of an occludin peptide.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577837

Essential function for the kinase TAK1 in innate and adaptive immune responses.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577837

Analysis of multiple-acquisition SSFP.

23 September 2018

1 reference

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Insights into the pathogenesis of cerebral lesions in incontinentia pigmenti.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577837

Tumour necrosis factor-alpha causes an increase in blood-brain barrier permeability during sepsis.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577837

NEMO/IKK gamma-deficient mice model incontinentia pigmenti.

23 September 2018

1 reference

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Characteristic MR findings in a neonate with incontinentia pigmenti.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577837

Canonical NF-κB Activity, Dispensable for B Cell Development, Replaces BAFF-Receptor Signals and Promotes B Cell Proliferation upon Activation

23 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1084%2FJEM.20150165

Inhibition of transcription factor NF-κB in the central nervous system ameliorates autoimmune encephalomyelitis in mice

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1084%2FJEM.20150165

[Lethal neurological involvement during incontinentia pigmenti]

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26347470

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

TNF-α/Fas-RIP-1-induced cell death signaling separates murine hematopoietic stem cells/progenitors into 2 distinct populations

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26347470

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1084/JEM.20150165

1 reference

12 August 2017

1 reference

12 August 2017

1 reference