Oxygen dependence of the cytotoxicity and metabolic activation of 4-alkylamino-5-nitroquinoline bioreductive drugs (Q36079717)

12 August 2017

Oxygen dependence of the cytotoxicity and metabolic activation of 4-alkylamino-5-nitroquinoline bioreductive drugs (English)

1 reference

12 August 2017

B G Siim

1

1 reference

12 August 2017

G J Atwell

series ordinal

2

1 reference

12 August 2017

W R Wilson

series ordinal

3

1 reference

12 August 2017

language of work or name

English

0 references

publication date

1 October 1994

1 reference

British Journal of Cancer

12 August 2017

1 reference

12 August 2017

70

1 reference

12 August 2017

4

1 reference

12 August 2017

596-603

1 reference

https://scigraph.springernature.com/pub.10.1038/bjc.1994.357

12 August 2017

0 references

cites work

The histological structure of some human lung cancers and the possible implications for radiotherapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2033401

Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: a review.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2033401

Oxygen in mammalian tissue: methods of measurement and affinities of various reactions

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2033401

Measurement of tumor hypoxia by invasive and non-invasive procedures: a review of recent clinical studies

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2033401

Studies on the mechanism of resistance to mitomycin C and porfiromycin in a human cell strain derived from a cancer-prone individual

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2033401

Comparisons of cellular radiation response using absolute rather than relative parameters

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2033401

The Enhanced Radiation Response of anin VitroTumour Model by Cyanide Released from Hydrolysed Amygdalin

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2033401

In situ detection of mycoplasma contamination in cell cultures by fluorescent Hoechst 33258 stain

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2033401

Intratumoral pO2 predicts survival in advanced cancer of the uterine cervix

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2033401

Studies on the Radiosensitizing Effect of Oxygen in Chinese Hamster Cells

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2033401

Measurement of low levels of oxygen and their effect on respiration in cell suspensions maintained in an open system.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2033401

Decreased NADPH:cytochrome P-450 reductase activity and impaired drug activation in a mammalian cell line resistant to mitomycin C under aerobic but not hypoxic conditions

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2033401

Pathophysiological approaches to identifying tumor hypoxia in patients

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2033401

DT-diaphorase activity and mitomycin C sensitivity in non-transformed cell strains derived from members of a cancer-prone family.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2033401

Chinese hamster ovary cell lines resistant to mitomycin C under aerobic but not hypoxic conditions are deficient in DT-diaphorase

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2033401

5-Nitro-4-(N,N-dimethylaminopropylamino)quinoline (5-nitraquine), a new DNA-affinic hypoxic cell radiosensitizer and bioreductive agent: comparison with nitracrine

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2033401

The Effects of Nitrobenzene Derivatives on Oxygen Utilization and Radiation Response of an in Vitro Tumor Model

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2033401

Adriamycin: A Possible Indirect Radiosensitizer of Hypoxic Tumor Cells

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2033401

Unusual oxygen concentration dependence of toxicity of SR-4233, a hypoxic cell toxin.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2033401

A rapid-mixing comparison of the mechanisms of radiosensitization by oxygen and misonidazole in CHO cells.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2033401

In vivo covalent binding of [14C]trinitrotoluene to proteins in the rat.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2033401

Exploiting tumor hypoxia through bioreductive release of diffusible cytotoxins: the cobalt(III)-nitrogen mustard complex SN 24771

23 September 2018

1 reference

12 December 2020

Effect of oxygen on misonidazole chemosensitization and cytotoxicity in vitro

1 reference

12 December 2020

Role of Oxygen in Modifying the Radiosensitivity of E. Coli B

1 reference

12 December 2020

Oxygen and exposure kinetics as factors influencing the cytotoxicity of porfiromycin, a mitomycin C analogue, in Chinese hamster ovary cells

1 reference

12 December 2020

Hypoxia-selective antitumor agents. 6. 4-(Alkylamino)nitroquinolines: a new class of hypoxia-selective cytotoxins

1 reference

12 December 2020

Modification of the cytotoxic activity of mitomycin C by oxygen and ascorbic acid in Chinese hamster ovary cells and a repair-deficient mutant

1 reference

12 December 2020

Targeting Bioreductive Drugs to Tumours: Is It Necessary to Manipulate Blood Flow

1 reference

12 December 2020

Chemosensitivity testing in V79 spheroids: drug delivery and cellular microenvironment

1 reference

12 December 2020

Oxygenation of human tumors: evaluation of tissue oxygen distribution in breast cancers by computerized O2 tension measurements

1 reference

12 December 2020

Measurement of steady-state values of respiration rate and oxidation levels of respiratory pigments at low oxygen tensions. A new technique

1 reference

12 December 2020

The respiration of ascites tumour cells at low oxygen concentrations

1 reference

12 December 2020

An experimental and analytical study of oxygen depletion in stirred cell suspensions

1 reference

12 December 2020

The sensitivity of human tumour cells to quinone bioreductive drugs: what role for DT-diaphorase?

1 reference

12 December 2020

Characteristics of the metabolism-induced binding of misonidazole to hypoxic mammalian cells

1 reference

12 December 2020

Differential cytotoxicity of diaziquone toward Chinese hamster ovary cells under hypoxic and aerobic exposure conditions

1 reference

12 December 2020

Oxygen tension, cellular respiration, and redox state as variables influencing the cytotoxicity of the radiosensitizer misonidazole

1 reference

12 December 2020

Identifiers

DOI

10.1038/BJC.1994.357

1 reference

12 August 2017

1 reference

12 August 2017

1 reference