Absence of selenoprotein P but not selenocysteine lyase results in severe neurological dysfunction (Q36074553)

12 August 2017

Absence of selenoprotein P but not selenocysteine lyase results in severe neurological dysfunction (English)

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12 August 2017

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7

M J Berry

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12 August 2017

A V Raman

1

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12 August 2017

M W Pitts

2

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12 August 2017

A Seyedali

3

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12 August 2017

A C Hashimoto

4

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12 August 2017

L A Seale

5

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12 August 2017

F P Bellinger

6

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12 August 2017

language of work or name

English

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publication date

3 May 2012

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Genes, Brain and Behavior

12 August 2017

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12 August 2017

11

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12 August 2017

5

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12 August 2017

601-613

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Expression and regulation of apolipoprotein E receptors in the cells of the central nervous system in culture: A review

12 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389215

A liver-derived secretory protein, selenoprotein P, causes insulin resistance.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389215

Mutations disrupting selenocysteine formation cause progressive cerebello-cerebral atrophy

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389215

Dietary selenium modulates activation and differentiation of CD4+ T cells in mice through a mechanism involving cellular free thiols

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389215

Selenium controls the sex-specific immune response and selenoprotein expression during the acute-phase response in mice

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389215

Regulation and function of selenoproteins in human disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389215

Sex differences in a hypoxia model of preterm brain damage

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389215

Identification of proteins interacting with selenocysteine lyase

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389215

Selenoprotein P-expression, functions, and roles in mammals

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389215

Association of selenoprotein p with Alzheimer's pathology in human cortex

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389215

Alternatively activated myeloid cells limit pathogenicity associated with African trypanosomiasis through the IL-10 inducible gene selenoprotein P.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389215

The selenoproteome exhibits widely varying, tissue-specific dependence on selenoprotein P for selenium supply

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389215

Neuronal and ependymal expression of selenoprotein P in the human brain

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389215

Sex and the pathogenesis of cerebral palsy

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389215

Genome-wide atlas of gene expression in the adult mouse brain

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389215

Altered hippocampus synaptic function in selenoprotein P deficient mice

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389215

Genistein affects androgen-responsive genes through both androgen- and estrogen-induced signaling pathways

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389215

Modulation of synaptic plasticity and memory by Reelin involves differential splicing of the lipoprotein receptor Apoer2

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389215

Selenoprotein P: an extracellular protein with unique physical characteristics and a role in selenium homeostasis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389215

Neurological dysfunction occurs in mice with targeted deletion of the selenoprotein P gene

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389215

Efficient selenium transfer from mother to offspring in selenoprotein-P-deficient mice enables dose-dependent rescue of phenotypes associated with selenium deficiency

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389215

Deletion of selenoprotein P alters distribution of selenium in the mouse

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389215

Identification of a novel exon in apolipoprotein E receptor 2 leading to alternatively spliced mRNAs found in cells of the vascular wall but not in neuronal tissue

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389215

The importance of selenium to human health

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389215

cDNA cloning, purification, and characterization of mouse liver selenocysteine lyase. Candidate for selenium delivery protein in selenoprotein synthesis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389215

Behavioral phenotyping of transgenic and knockout mice: experimental design and evaluation of general health, sensory functions, motor abilities, and specific behavioral tests

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389215

Analysis of the mouse selenoprotein P gene

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389215

Developments of a water-maze procedure for studying spatial learning in the rat

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389215

Selenocysteine lyase, a novel enzyme that specifically acts on selenocysteine. Mammalian distribution and purification and properties of pig liver enzyme.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389215

Progression of neurodegeneration and morphologic changes in the brains of juvenile mice with selenoprotein P deleted

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389215

Hepatically derived selenoprotein P is a key factor for kidney but not for brain selenium supply

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389215

Gene disruption discloses role of selenoprotein P in selenium delivery to target tissues

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389215

Deletion of apolipoprotein E receptor-2 in mice lowers brain selenium and causes severe neurological dysfunction and death when a low-selenium diet is fed.

27 July 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1601-183X.2012.00794.X

Mutation of megalin leads to urinary loss of selenoprotein P and selenium deficiency in serum, liver, kidneys and brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1601-183X.2012.00794.X

Profiling of mouse synaptosome proteome and phosphoproteome by IEF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1601-183X.2012.00794.X

Early and progressive sensorimotor anomalies in mice overexpressing wild-type human alpha-synuclein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1601-183X.2012.00794.X

Serum concentrations of beta-carotene, vitamins C and E, zinc and selenium are influenced by sex, age, diet, smoking status, alcohol consumption and corpulence in a general French adult population

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1601-183X.2012.00794.X

The selenium-rich C-terminal domain of mouse selenoprotein P is necessary for the supply of selenium to brain and testis but not for the maintenance of whole body selenium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1601-183X.2012.00794.X

Hepatic selenoprotein P (SePP) expression restores selenium transport and prevents infertility and motor-incoordination in Sepp-knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1601-183X.2012.00794.X

Selenium-dependent pre- and posttranscriptional mechanisms are responsible for sexual dimorphic expression of selenoproteins in murine tissues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1601-183X.2012.00794.X

Neurodegeneration in mice resulting from loss of functional selenoprotein P or its receptor apolipoprotein E receptor 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1601-183X.2012.00794.X

Comparative analysis of selenocysteine machinery and selenoproteome gene expression in mouse brain identifies neurons as key functional sites of selenium in mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1601-183X.2012.00794.X

All regions of mouse brain are dependent on selenoprotein P for maintenance of selenium.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389215

Mammalian selenocysteine lyase is involved in selenoprotein biosynthesis

23 September 2018

1 reference

12 December 2020

Genetic polymorphisms in the human selenoprotein P gene determine the response of selenoprotein markers to selenium supplementation in a gender-specific manner (the SELGEN study)

1 reference

12 December 2020

Escherichia coli NifS-like proteins provide selenium in the pathway for the biosynthesis of selenophosphate

1 reference

12 December 2020

Differential responses to selenomethionine supplementation by sex and genotype in healthy adults

1 reference

12 December 2020

Effects of selenium deficiency on testicular morphology and function in rats

1 reference

12 December 2020

Brainstem axonal degeneration in mice with deletion of selenoprotein p

1 reference

12 December 2020

Effects of dietary selenite, selenocystine and selenomethionine on selenocysteine lyase and glutathione peroxidase activities and on selenium levels in rat tissues

1 reference

12 December 2020

10.1111/J.1601-183X.2012.00794.X

Identifiers

DOI

1 reference

12 August 2017

1 reference

12 August 2017

PubMed publication ID

22487427

1 reference