Mutant NADH dehydrogenase subunit 4 gene delivery to mitochondria by targeting sequence-modified adeno-associated virus induces visual loss and optic atrophy in mice (Q36073893)

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English	Mutant NADH dehydrogenase subunit 4 gene delivery to mitochondria by targeting sequence-modified adeno-associated virus induces visual loss and optic atrophy in mice	scientific article

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7 February 2020

Mutant NADH dehydrogenase subunit 4 gene delivery to mitochondria by targeting sequence-modified adeno-associated virus induces visual loss and optic atrophy in mice (English)

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7 February 2020

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Hong Yu

1

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7 February 2020

Sacide S Ozdemir

2

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7 February 2020

Rajeshwari D Koilkonda

3

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7 February 2020

Tsung-Han Chou

4

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7 February 2020

Vittorio Porciatti

5

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7 February 2020

Vince Chiodo

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7 February 2020

Sanford L Boye

7

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7 February 2020

William W Hauswirth

8

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7 February 2020

Alfred S Lewin

9

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7 February 2020

John Guy

10

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7 February 2020

publication date

20 June 2012

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7 February 2020

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16

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Molecular Vision

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7 February 2020

18

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7 February 2020

1668-1683

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7 February 2020

Animal models of human mitochondrial DNA mutations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388991

2 October 2017

Leber's Hereditary Optic Neuropathy-Gene Therapy: From Benchtop to Bedside

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388991

2 October 2017

Mitochondrial matrix delivery using MITO-Porter, a liposome-based carrier that specifies fusion with mitochondrial membranes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388991

2 October 2017

Targeted nucleic acid delivery to mitochondria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388991

2 October 2017

Mitochondrial gene replacement in primate offspring and embryonic stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388991

2 October 2017

NDUFS4: creation of a mouse model mimicking a Complex I disorder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388991

2 October 2017

Efficiency and safety of AAV-mediated gene delivery of the human ND4 complex I subunit in the mouse visual system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388991

2 October 2017

Optimized allotopic expression of the human mitochondrial ND4 prevents blindness in a rat model of mitochondrial dysfunction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388991

2 October 2017

Progress and prospects: gene therapy for mitochondrial DNA disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388991

2 October 2017

Mice with mitochondrial complex I deficiency develop a fatal encephalomyopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388991

2 October 2017

Mitochondrial disorders in the nervous system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388991

2 October 2017

Mitochondrial drug delivery and mitochondrial disease therapy--an approach to liposome-based delivery targeted to mitochondria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388991

2 October 2017

Adeno-associated virus type 2 VP2 capsid protein is nonessential and can tolerate large peptide insertions at its N terminus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388991

2 October 2017

Mitochondrial dysfunction as a cause of optic neuropathies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388991

2 October 2017

Plant mitochondria actively import DNA via the permeability transition pore complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388991

2 October 2017

Leber's hereditary optic neuropathy differentially affects smaller axons in the optic nerve.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388991

2 October 2017

Production and purification of recombinant adeno-associated virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388991

2 October 2017

Two distinct mechanisms drive protein translocation across the mitochondrial outer membrane in the late step of the cytochrome b(2) import pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388991

2 October 2017

MITOMAP: a human mitochondrial genome database

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388991

2 October 2017

Mitochondrial DNA mutation associated with Leber's hereditary optic neuropathy

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388991

2 October 2017

Helper-free stocks of recombinant adeno-associated viruses: normal integration does not require viral gene expression

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2 October 2017

Suppression of complex I gene expression induces optic neuropathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388991

11 July 2018

Leber hereditary optic neuropathy: mitochondrial mutations and degeneration of the optic nerve

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388991

11 July 2018

The mutant human ND4 subunit of complex I induces optic neuropathy in the mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388991

23 September 2018

Natural competence of mammalian mitochondria allows the molecular investigation of mitochondrial gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388991

23 September 2018

Targeted delivery of DNA to the mitochondrial compartment via import sequence-conjugated peptide nucleic acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388991

23 September 2018

Rescue of a mitochondrial deficiency causing Leber Hereditary Optic Neuropathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388991

23 September 2018

Resolution of the Membrane Domain of Bovine Complex I into Subcomplexes: Implications for the Structural Organization of the Enzyme

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https://pubmed.ncbi.nlm.nih.gov/22773905

12 December 2020

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The epidemiology of pathogenic mitochondrial DNA mutations

1 reference

https://pubmed.ncbi.nlm.nih.gov/22773905

12 December 2020

based on heuristic

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7 February 2020

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22773905%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

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