Peroxisome proliferator-activated receptor alpha and hypertensive heart disease (Q36070408)

12 August 2017

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title

Peroxisome proliferator-activated receptor alpha and hypertensive heart disease (English)

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12 August 2017

Maria J Goikoetxea

1

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PubMed ID

15765888

12 August 2017

Javier Beaumont

series ordinal

2

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PubMed ID

15765888

12 August 2017

Javier Díez

series ordinal

3

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12 August 2017

1 January 2004

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12 August 2017

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12 August 2017

64 Suppl 2

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12 August 2017

9-18

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https://scigraph.springernature.com/pub.10.2165/00003495-200464002-00003

12 August 2017

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cites work

Peroxisome proliferator-activated receptor alpha in metabolic disease, inflammation, atherosclerosis and aging

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12 December 2020

The cellular pathophysiology of progression to heart failure.

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12 December 2020

Peroxisome proliferator-activated receptor alpha target genes

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12 December 2020

Hypoxia in vivo decreases peroxisome proliferator-activated receptor alpha-regulated gene expression in rat heart

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12 December 2020

The coactivator PGC-1 cooperates with peroxisome proliferator-activated receptor alpha in transcriptional control of nuclear genes encoding mitochondrial fatty acid oxidation enzymes

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12 December 2020

The role of the peroxisome proliferator-activated receptor alpha (PPAR alpha) in the control of cardiac lipid metabolism

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12 December 2020

Rat PPARs: quantitative analysis in adult rat tissues and regulation in fasting and refeeding.

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12 December 2020

Hypoxia inhibits the peroxisome proliferator-activated receptor alpha/retinoid X receptor gene regulatory pathway in cardiac myocytes: a mechanism for O2-dependent modulation of mitochondrial fatty acid oxidation

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12 December 2020

Peroxisome proliferator-activated receptor gamma activators inhibit cardiac hypertrophy in cardiac myocytes

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12 December 2020

Angiotensin II is associated with activation of NF-kappaB-mediated genes and downregulation of PPARs

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12 December 2020

Simvastatin inhibits cardiac hypertrophy and angiotensin-converting enzyme activity in rats with aortic stenosis

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12 December 2020

Aging-induced decrease in the PPAR-alpha level in hearts is improved by exercise training

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12 December 2020

The human peroxisome proliferator-activated receptor alpha gene: identification and functional characterization of two natural allelic variants.

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12 December 2020

Peroxisome proliferator-activated receptor activators inhibit lipopolysaccharide-induced tumor necrosis factor-alpha expression in neonatal rat cardiac myocytes

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12 December 2020

Peroxisome proliferator activated receptor-alpha expression in human liver.

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12 December 2020

Peroxisome proliferator-activated receptor alpha is downregulated in the failing human heart

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12 December 2020

The cardiac phenotype induced by PPARalpha overexpression mimics that caused by diabetes mellitus

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12 December 2020

Peroxisome proliferator-activated receptors in vascular biology and atherosclerosis: emerging insights for evolving paradigms

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12 December 2020

Statin-induced inhibition of the Rho-signaling pathway activates PPARalpha and induces HDL apoA-I

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12 December 2020

Peroxisome proliferator--activated receptor alpha gene regulates left ventricular growth in response to exercise and hypertension

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12 December 2020

Ceramide is involved in triggering of cardiomyocyte apoptosis induced by ischemia and reperfusion

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12 December 2020

Prophylaxis of early ventricular fibrillation by inhibition of acylcarnitine accumulation

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12 December 2020

Fenofibrate, a peroxisome proliferator-activated receptor alpha activator, suppresses experimental autoimmune myocarditis by stimulating the interleukin-10 pathway in rats

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12 December 2020

Epidemiology of heart failure

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12 December 2020

PPAR alpha activator fenofibrate inhibits myocardial inflammation and fibrosis in angiotensin II-infused rats

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12 December 2020

Peroxisome proliferator-activated receptor alpha as a genetic determinant of cardiac hypertrophic growth: culprit or innocent bystander?

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12 December 2020

Peroxisome proliferator-activated receptor alpha (PPARalpha) signaling in the gene regulatory control of energy metabolism in the normal and diseased heart

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12 December 2020

cDNA cloning, chromosomal mapping, and functional characterization of the human peroxisome proliferator activated receptor

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12 December 2020

Simvastatin induces regression of cardiac hypertrophy and fibrosis and improves cardiac function in a transgenic rabbit model of human hypertrophic cardiomyopathy

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12 December 2020

Extracellular matrix remodeling in heart failure: a role for de novo angiotensin II generation

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12 December 2020

Transcriptional effects of chronic Akt activation in the heart.

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12 December 2020

Inherited cardiomyopathies

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12 December 2020

Absolute concentrations of high-energy phosphate metabolites in normal, hypertrophied, and failing human myocardium measured noninvasively with (31)P-SLOOP magnetic resonance spectroscopy

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12 December 2020

Metabolically-modulated growth and phenotype of the rat heart

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12 December 2020

Transcriptional activation of energy metabolic switches in the developing and hypertrophied heart

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12 December 2020

Amelioration of angiotensin II-induced cardiac injury by a 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitor

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12 December 2020

Retinoid-dependent pathways suppress myocardial cell hypertrophy.

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12 December 2020

Peroxisome proliferator-activated receptors: three isotypes for a multitude of functions

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12 December 2020

Deactivation of peroxisome proliferator-activated receptor-alpha during cardiac hypertrophic growth

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12 December 2020

Peroxisome proliferator-activated receptor gamma plays a critical role in inhibition of cardiac hypertrophy in vitro and in vivo

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12 December 2020

A role for Sp and nuclear receptor transcription factors in a cardiac hypertrophic growth program

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12 December 2020

Peroxisome proliferator-activated receptor (PPAR) alpha and PPARbeta/delta, but not PPARgamma, modulate the expression of genes involved in cardiac lipid metabolism

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12 December 2020

Expression of the mRNA encoding truncated PPAR alpha does not correlate with hepatic insensitivity to peroxisome proliferators

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12 December 2020

Energy metabolism in the normal and failing heart: potential for therapeutic interventions

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12 December 2020

Constitutive regulation of cardiac fatty acid metabolism through peroxisome proliferator-activated receptor alpha associated with age-dependent cardiac toxicity

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12 December 2020

Myocardial fatty acid metabolism: independent predictor of left ventricular mass in hypertensive heart disease

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12 December 2020

Left-ventricular diastolic dysfunction may be prevented by chronic treatment with PPAR-alpha or -gamma agonists in a type 2 diabetic animal model.

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12 December 2020

Peroxisome proliferator-activated receptor-alpha and receptor-gamma activators prevent cardiac fibrosis in mineralocorticoid-dependent hypertension

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12 December 2020

Lipophilic HMG-CoA reductase inhibitor has an anti-inflammatory effect: reduction of MRNA levels for interleukin-1beta, interleukin-6, cyclooxygenase-2, and p22phox by regulation of peroxisome proliferator-activated receptor alpha (PPARalpha) in pri

1 reference

12 December 2020

Pioglitazone, a peroxisome proliferator-activated receptor-gamma agonist, attenuates left ventricular remodeling and failure after experimental myocardial infarction

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12 December 2020

Atorvastatin treatment induced peroxisome proliferator-activated receptor alpha expression and decreased plasma nonesterified fatty acids and liver triglyceride in fructose-fed rats

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12 December 2020

Altered myocardial fatty acid and glucose metabolism in idiopathic dilated cardiomyopathy.

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12 December 2020

A novel mouse model of lipotoxic cardiomyopathy

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12 December 2020

Variation in the PPARα gene is associated with altered function in vitro and plasma lipid concentrations in Type II diabetic subjects

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12 December 2020

Apoptosis in hypertensive heart disease

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12 December 2020

Peroxisome proliferator-activated receptors: vascular and cardiac effects in hypertension

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12 December 2020

Downregulation of myocardial myocyte enhancer factor 2C and myocyte enhancer factor 2C-regulated gene expression in diabetic patients with nonischemic heart failure

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12 December 2020

Peroxisome proliferator activated receptor (PPAR)alpha agonists inhibit hypertrophy of neonatal rat cardiac myocytes

1 reference

12 December 2020

p38 mitogen-activated protein kinase activates peroxisome proliferator-activated receptor alpha: a potential role in the cardiac metabolic stress response

1 reference

12 December 2020

Stimulation of peroxisome-proliferator-activated receptor alpha (PPAR alpha) attenuates cardiac fibrosis and endothelin-1 production in pressure-overloaded rat hearts

1 reference

12 December 2020

Endothelin-1-induced cardiac hypertrophy is inhibited by activation of peroxisome proliferator-activated receptor-alpha partly via blockade of c-Jun NH2-terminal kinase pathway

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12 December 2020

Metabolic gene expression in fetal and failing human heart

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12 December 2020

The progression from hypertension to congestive heart failure

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12 December 2020

Reactivation of peroxisome proliferator-activated receptor alpha is associated with contractile dysfunction in hypertrophied rat heart

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12 December 2020

Defective fatty acid uptake in the spontaneously hypertensive rat is a primary determinant of altered glucose metabolism, hyperinsulinemia, and myocardial hypertrophy

1 reference

12 December 2020

Brief report: a deficiency of carnitine-acylcarnitine translocase in the inner mitochondrial membrane

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12 December 2020

PPAR signaling in the control of cardiac energy metabolism

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12 December 2020

Overview of hemodynamic and non-hemodynamic factors associated with left ventricular hypertrophy

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12 December 2020

Polarity and specific sequence requirements of peroxisome proliferator-activated receptor (PPAR)/retinoid X receptor heterodimer binding to DNA. A functional analysis of the malic enzyme gene PPAR response element

1 reference

12 December 2020

A truncated human peroxisome proliferator-activated receptor alpha splice variant with dominant negative activity.

1 reference

12 December 2020

Induction of the peroxisome proliferator activated receptor by fenofibrate in rat liver

1 reference

12 December 2020

Morphologic, hemodynamic and coronary perfusion characteristics in severe left ventricular hypertrophy secondary to systemic hypertension and evidence for nonatherosclerotic myocardial ischemia.

1 reference

12 December 2020

10.2165/00003495-200464002-00003

Identifiers

DOI

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Dimensions Publication ID

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1 reference

PubMed ID

15765888