Specific mitochondrial DNA mutation in mice regulates diabetes and lymphoma development (Q36069084)

12 August 2017

Specific mitochondrial DNA mutation in mice regulates diabetes and lymphoma development (English)

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12 August 2017

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Osamu Hashizume

1

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12 August 2017

Akinori Shimizu

2

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12 August 2017

Mutsumi Yokota

3

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12 August 2017

Atsuko Sugiyama

4

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12 August 2017

Kazuto Nakada

5

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12 August 2017

Hiroyuki Miyoshi

6

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12 August 2017

Makiko Itami

7

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12 August 2017

Miki Ohira

8

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12 August 2017

Hiroki Nagase

9

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12 August 2017

Keizo Takenaga

10

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12 August 2017

Jun-Ichi Hayashi

11

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12 August 2017

language of work or name

English

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publication date

11 June 2012

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Proceedings of the National Academy of Sciences of the United States of America

12 August 2017

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12 August 2017

109

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12 August 2017

26

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12 August 2017

10528-10533

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Otto Warburg's contributions to current concepts of cancer metabolism

12 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387115

Heteroplasmic mitochondrial DNA mutations in normal and tumour cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387115

Oxidative stress and oxidative damage in carcinogenesis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387115

Mitochondrial DNA mutations and aging: devils in the details?

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387115

Enhanced glycolysis induced by mtDNA mutations does not regulate metastasis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387115

The Mouse Tumor Biology database

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387115

ROS-generating mitochondrial DNA mutations can regulate tumor cell metastasis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387115

Analysis of transformation and tumorigenicity using mouse embryonic fibroblast cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387115

Generation of trans-mitochondrial mice carrying homoplasmic mtDNAs with a missense mutation in a structural gene using ES cells.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387115

The mitochondrial theory of aging and its relationship to reactive oxygen species damage and somatic mtDNA mutations

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387115

Somatic mtDNA mutations cause aging phenotypes without affecting reactive oxygen species production

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387115

Mitochondrial tumour suppressors: a genetic and biochemical update

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387115

Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387115

Mitochondrial DNA mutations in human disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387115

Mechanisms of B-cell lymphoma pathogenesis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387115

mtDNA mutations increase tumorigenicity in prostate cancer

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387115

Premature ageing in mice expressing defective mitochondrial DNA polymerase

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387115

Mitochondrial diabetes: molecular mechanisms and clinical presentation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387115

Quantitative studies of the growth of mouse embryo cells in culture and their development into established lines

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387115

Are oxidative stress-activated signaling pathways mediators of insulin resistance and beta-cell dysfunction?

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387115

Mitochondrial function in normal and diabetic beta-cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387115

Facile detection of mitochondrial DNA mutations in tumors and bodily fluids

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387115

Mutations in SDHD, a mitochondrial complex II gene, in hereditary paraganglioma

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387115

Mitochondrial diseases in man and mouse

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387115

Somatic mutations of the mitochondrial genome in human colorectal tumours

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387115

Cancer resistance genes in mice: models for the study of tumour modifiers

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387115

Generation of trans-mitochondrial mito-mice by the introduction of a pathogenic G13997A mtDNA from highly metastatic lung carcinoma cells.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387115

Genetic background controls tumor development in PTEN-deficient mice.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387115

Positive contribution of pathogenic mutations in the mitochondrial genome to the promotion of cancer by prevention from apoptosis.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387115

Nuclear DNA but not mtDNA controls tumor phenotypes in mouse cells

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387115

Accumulation of pathogenic DeltamtDNA induced deafness but not diabetic phenotypes in mito-mice

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387115

The mitochondrial theory of aging: dead or alive?

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387115

Mutations in SDHC cause autosomal dominant paraganglioma, type 3.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387115

Generation of mice with mitochondrial dysfunction by introducing mouse mtDNA carrying a deletion into zygotes

23 September 2018

1 reference

12 December 2020

Mitochondria: integrators in tumorigenesis?

1 reference

12 December 2020

Genetic background alters the spectrum of tumors that develop in p53-deficient mice

1 reference

12 December 2020

Pathogenetic aspects of the A8344G mutation of mitochondrial DNA associated with MERRF syndrome and multiple symmetric lipomas

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1202367109

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12 August 2017

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12 August 2017

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