Elevated level of spindle checkprotein MAD2 correlates with cellular mitotic arrest, but not with aneuploidy and clinicopathological characteristics in gastric cancer. (Q36066030)

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English	Elevated level of spindle checkprotein MAD2 correlates with cellular mitotic arrest, but not with aneuploidy and clinicopathological characteristics in gastric cancer.	scientific article

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4 January 2020

Elevated level of spindle checkprotein MAD2 correlates with cellular mitotic arrest, but not with aneuploidy and clinicopathological characteristics in gastric cancer (English)

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4 January 2020

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4 January 2020

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Chew-Wun Wu

1

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4 January 2020

Chin-Wen Chi

2

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1 November 2004

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4 January 2020

World Journal of Gastroenterology

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4 January 2020

10

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4 January 2020

3240-3244

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4 January 2020

22

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4 January 2020

The two histological main types of gastric carcinoma: diffuse and so called intestinal-type carcinoma: an attempt at a histo-clinical classification

1 reference

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2 October 2017

Microtubules, microtubule-interfering agents and apoptosis.

1 reference

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2 October 2017

Expression of estrogen receptor and estrogen receptor messenger RNA in gastric carcinoma tissues

1 reference

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2 October 2017

Centromeres and kinetochores: from epigenetics to mitotic checkpoint signaling

1 reference

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Chromosome instability in human lung cancers: possible underlying mechanisms and potential consequences in the pathogenesis

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2 October 2017

Cytoplasmic dynein/dynactin drives kinetochore protein transport to the spindle poles and has a role in mitotic spindle checkpoint inactivation

1 reference

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2 October 2017

Aneuploid colon cancer cells have a robust spindle checkpoint

1 reference

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2 October 2017

Mammalian mad2 and bub1/bubR1 recognize distinct spindle-attachment and kinetochore-tension checkpoints

1 reference

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2 October 2017

Visualization of Mad2 dynamics at kinetochores, along spindle fibers, and at spindle poles in living cells

1 reference

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2 October 2017

Chromosome missegregation and apoptosis in mice lacking the mitotic checkpoint protein Mad2

1 reference

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2 October 2017

Mutation analysis of hBUB1 in aneuploid HNSCC and lung cancer cell lines

1 reference

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Characterization of MAD2B and other mitotic spindle checkpoint genes

1 reference

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Mad2 transiently associates with an APC/p55Cdc complex during mitosis

1 reference

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2 October 2017

The human homologue of Bub3 is required for kinetochore localization of Bub1 and a Mad3/Bub1-related protein kinase

1 reference

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The checkpoint protein MAD2 and the mitotic regulator CDC20 form a ternary complex with the anaphase-promoting complex to control anaphase initiation

1 reference

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Mammalian p55CDC mediates association of the spindle checkpoint protein Mad2 with the cyclosome/anaphase-promoting complex, and is involved in regulating anaphase onset and late mitotic events

1 reference

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Microinjection of antibody to Mad2 protein into mammalian cells in mitosis induces premature anaphase

1 reference

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2 October 2017

Mutations of mitotic checkpoint genes in human cancers

1 reference

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2 October 2017

MAD2 associates with the cyclosome/anaphase-promoting complex and inhibits its activity

1 reference

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2 October 2017

Identification of a human mitotic checkpoint gene: hsMAD2

1 reference

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Genomic instability at the BUB1 locus in colorectal cancer, but not in non-small cell lung cancer.

1 reference

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11 July 2018

Coupling cell division and cell death to microtubule dynamics

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Prognostic significance of p53, nm23, PCNA and c-erbB-2 in gastric cancer

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23 September 2018

Overexpression of the mitotic checkpoint genes BUB1, BUBR1, and BUB3 in gastric cancer--association with tumour cell proliferation.

1 reference

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Mechanisms of aneuploidy in thyroid cancer cell lines and tissues: evidence for mitotic checkpoint dysfunction without mutations in BUB1 and BUBR1.

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Frequent impairment of the spindle assembly checkpoint in hepatocellular carcinoma.

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Mutational inactivation of mitotic checkpoint genes, hsMAD2 and hBUB1, is rare in sporadic digestive tract cancers.

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10.3748/WJG.V10.I22.3240

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4 January 2020

1 reference

Europe PubMed Central

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4 January 2020

1 reference

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4 January 2020

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