Co-expression of cytokine and suicide genes to enhance the activity and safety of tumor-specific cytotoxic T lymphocytes. (Q36059585)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17638856%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

title

Co-expression of cytokine and suicide genes to enhance the activity and safety of tumor-specific cytotoxic T lymphocytes (English)

1 reference

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2 January 2020

0 references

0 references

1

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2 January 2020

Martin Pule

5

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2 January 2020

8

Cliona M Rooney

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2 January 2020

9

Malcolm K Brenner

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2 January 2020

7

Helen E Heslop

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2 January 2020

3

Barbara Savoldo

1 reference

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2 January 2020

10

Gianpietro Dotti

1 reference

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Greta M P Giordano Attianese

2 January 2020

4

object named as

Greta M P Giordano Attianese

1 reference

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2 January 2020

author name string

Juan F Vera

2

1 reference

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2 January 2020

Aaron E Foster

6

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2 January 2020

language of work or name

English

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publication date

17 July 2007

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2 January 2020

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2 January 2020

volume

110

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2 January 2020

issue

8

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2 January 2020

page(s)

2793-2802

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Epstein Barr virus specific cytotoxic T lymphocytes expressing the anti-CD30zeta artificial chimeric T-cell receptor for immunotherapy of Hodgkin disease

2 January 2020

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Cytokine-independent growth and clonal expansion of a primary human CD8+ T-cell clone following retroviral transduction with the IL-15 gene

2 October 2017

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T lymphocytes redirected against the kappa light chain of human immunoglobulin efficiently kill mature B lymphocyte-derived malignant cells

2 October 2017

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Treatment of solid organ transplant recipients with autologous Epstein Barr virus-specific cytotoxic T lymphocytes (CTLs)

2 October 2017

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IL-2 administration increases CD4+ CD25(hi) Foxp3+ regulatory T cells in cancer patients

2 October 2017

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Primary human T lymphocytes engineered with a codon-optimized IL-15 gene resist cytokine withdrawal-induced apoptosis and persist long-term in the absence of exogenous cytokine

2 October 2017

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Responses to human CD40 ligand/human interleukin-2 autologous cell vaccine in patients with B-cell chronic lymphocytic leukemia

2 October 2017

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Human cytotoxic T lymphocytes with reduced sensitivity to Fas-induced apoptosis.

2 October 2017

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Cytotoxic T lymphocyte therapy for Epstein-Barr virus+ Hodgkin's disease

2 October 2017

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Multimodality imaging of lymphocytic migration using lentiviral-based transduction of a tri-fusion reporter gene.

2 October 2017

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Distinct IL-2 receptor signaling pattern in CD4+CD25+ regulatory T cells

2 October 2017

1 reference

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IL-15 enhances the in vivo antitumor activity of tumor-reactive CD8+ T cells

2 October 2017

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LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1

2 October 2017

1 reference

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The main function of IL-2 is to promote the development of T regulatory cells

2 October 2017

1 reference

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Adoptive-cell-transfer therapy for the treatment of patients with cancer

2 October 2017

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Adoptive T cell therapy using antigen-specific CD8+ T cell clones for the treatment of patients with metastatic melanoma: in vivo persistence, migration, and antitumor effect of transferred T cells

2 October 2017

1 reference

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Autologous Epstein-Barr virus (EBV)-specific cytotoxic T cells for the treatment of persistent active EBV infection

2 October 2017

1 reference

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Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes

2 October 2017

1 reference

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Transduction of an IL-2 gene into human melanoma-reactive lymphocytes results in their continued growth in the absence of exogenous IL-2 and maintenance of specific antitumor activity

2 October 2017

1 reference

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Fatal leukemia in interleukin-15 transgenic mice.

2 October 2017

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Two subsets of memory T lymphocytes with distinct homing potentials and effector functions

2 October 2017

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Human Epstein-Barr virus (EBV)-specific cytotoxic T lymphocytes home preferentially to and induce selective regressions of autologous EBV-induced B cell lymphoproliferations in xenografted C.B-17 scid/scid mice

2 October 2017

1 reference

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Controlling signal transduction with synthetic ligands

2 October 2017

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Inducible caspase 9 suicide gene to improve the safety of allodepleted T cells after haploidentical stem cell transplantation

2 October 2017

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An inducible caspase 9 safety switch for T-cell therapy

11 July 2018

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Use of gene-modified virus-specific T lymphocytes to control Epstein-Barr-virus-related lymphoproliferation

11 July 2018

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Retroviral expression of the human IL-2 gene in a murine T cell line results in cell growth autonomy and tumorigenicity

11 July 2018

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Cell therapy of stage IV nasopharyngeal carcinoma with autologous Epstein-Barr virus-targeted cytotoxic T lymphocytes.

11 July 2018

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Treatment of nasopharyngeal carcinoma with Epstein-Barr virus--specific T lymphocytes

23 September 2018

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Correction of multi-gene deficiency in vivo using a single 'self-cleaving' 2A peptide-based retroviral vector

23 September 2018

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A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency

23 September 2018

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RD114-pseudotyped oncoretroviral vectors. Biological and physical properties.

23 September 2018

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The 'cleavage' activities of foot-and-mouth disease virus 2A site-directed mutants and naturally occurring '2A-like' sequences

23 September 2018

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Infusion of cytotoxic T cells for the prevention and treatment of Epstein-Barr virus-induced lymphoma in allogeneic transplant recipients.

23 September 2018

1 reference

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Epstein-Barr virus (EBV)-specific cytotoxic T lymphocytes for the treatment of patients with EBV-positive relapsed Hodgkin's disease

23 September 2018

1 reference

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Analysis of the aphthovirus 2A/2B polyprotein ‘cleavage’ mechanism indicates not a proteolytic reaction, but a novel translational effect: a putative ribosomal ‘skip’

23 September 2018

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12 December 2020

Intravenous safety and pharmacokinetics of a novel dimerizer drug, AP1903, in healthy volunteers

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12 December 2020

Adoptive transfer of cloned melanoma-reactive T lymphocytes for the treatment of patients with metastatic melanoma

1 reference

12 December 2020

Effect of scaffold attachment region on transgene expression in retrovirus vector-transduced primary T cells and macrophages

1 reference

12 December 2020

The long signal peptide isoform and its alternative processing direct the intracellular trafficking of interleukin-15

1 reference

12 December 2020

10.1182/BLOOD-2007-02-072843

Identifiers

DOI

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2 January 2020

1 reference

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2 January 2020

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