Morphine and morphine-6-glucuronide in the plasma and cerebrospinal fluid of children (Q36054979)

11 August 2017

Morphine and morphine-6-glucuronide in the plasma and cerebrospinal fluid of children (English)

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11 August 2017

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R D Hain

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11 August 2017

A Hardcastle

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2

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11 August 2017

C R Pinkerton

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3

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11 August 2017

G W Aherne

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4

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11 August 2017

language of work or name

English

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publication date

1 July 1999

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British Journal of Clinical Pharmacology

11 August 2017

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11 August 2017

48

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11 August 2017

1

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11 August 2017

37-42

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Morphine glucuronidation in premature neonates

11 August 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014881

Pharmacokinetics of morphine infusion in premature neonates

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014881

Management of common opioid side effects during long-term therapy of cancer pain

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014881

An improved method for the simultaneous determination of morphine and its principal glucuronide metabolites

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014881

Studies on morphine disposition: influence of general anaesthesia on plasma concentrations of morphine and its metabolites

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014881

Multiple mu opiate receptors

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014881

The bioavailability and pharmacokinetics of morphine after intravenous, oral and buccal administration in healthy volunteers

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014881

The pharmacologic management of pain in children

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014881

Analgesic efficacy and CSF pharmacokinetics of intrathecal morphine-6-glucuronide: comparison with morphine

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014881

Morphine and metabolite behavior after different routes of morphine administration: demonstration of the importance of the active metabolite morphine-6-glucuronide

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014881

Morphine-6-glucuronide: effects on ventilation in normal volunteers

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014881

The analgesic activity of morphine-6-glucuronide

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014881

Explanation at the opioid receptor level for differing toxicity of morphine and morphine 6-glucuronide

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014881

Morphine pharmacokinetics in early infancy.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014881

Morphine-6-glucuronide: analgesic effects and receptor binding profile in rats.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014881

Morphine metabolism in children

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014881

Antinociceptive and ventilatory effects of the morphine metabolites: morphine-6-glucuronide and morphine-3-glucuronide

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014881

Morphine 6-glucuronide and morphine 3-glucuronide as molecular chameleons with unexpected lipophilicity.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014881

Chronic morphine therapy for cancer pain: plasma and cerebrospinal fluid morphine and morphine-6-glucuronide concentrations.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014881

Morphine kinetics after diamorphine infusion in premature neonates

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014881

Morphine metabolism in neonates and infants

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014881

Kinetics of intravenous and intramuscular morphine

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014881

Morphine kinetics in children

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014881

Pharmacokinetics of intravenous morphine in patients anesthetized with enflurane-nitrous oxide.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014881

Pharmacokinetics of intravenous morphine in balanced anesthesia: studies in children.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014881

Morphine-6-glucuronide, a potent mu agonist.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014881

Pharmacological characterization of morphine-6 beta-glucuronide, a very potent morphine metabolite.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014881

Analgesic Effect of Morphine Glucuronides

23 September 2018

1 reference

12 December 2020

A Specific Radioimmunoassay for the Determination of Morphine-6-Glucuronide in Human Plasma

1 reference

12 December 2020

Morphine glucuronidation in human fetal and adult liver

1 reference

12 December 2020

Pharmacokinetics of single-dose i.v. morphine in normal volunteers and patients with end-stage renal failure

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12 December 2020

CSF and plasma pharmacokinetics of intramuscular morphine

1 reference

12 December 2020

Variation in morphine pharmacokinetics in children with cancer

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12 December 2020

Explanation for potency of repeated oral doses of morphine?

1 reference

12 December 2020

Cerebrospinal fluid and plasma pharmacokinetics of morphine infusions in pediatric cancer patients and rhesus monkeys

1 reference

12 December 2020

Potential analgesic contribution from morphine-6-glucuronide in CSF

1 reference

12 December 2020

Analgesic activity of morphine-6-glucuronide

1 reference

12 December 2020

Kinetics and dynamics of postoperative intravenous morphine in children

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12 December 2020

Pharmacokinetics of a single dose of morphine in preterm infants during the first week of life

1 reference

12 December 2020

Toxicity and pharmacokinetics of morphine and morphine-6-glucuronide

1 reference

12 December 2020

Plasma morphine and morphine-6-glucuronide during chronic morphine therapy for cancer pain: plasma profiles, steady-state concentrations and the consequences of renal failure

1 reference

12 December 2020

M6G and its analgesic action in chronic use

1 reference

12 December 2020

The Maturation of Morphine Clearance and Metabolism

1 reference

12 December 2020

Analgesia in children with sickle cell crisis: comparison of intermittent opioids vs. continuous intravenous infusion of morphine and placebo-controlled study of oxygen inhalation

1 reference

12 December 2020

Evaluation of a differential radioimmunoassay technique for the determination of morphine and morphine-6-glucuronide in human plasma

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12 December 2020

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12 December 2020

10.1046/J.1365-2125.1999.00948.X

Identifiers

DOI

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11 August 2017

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11 August 2017

PubMed publication ID

10383558

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