Isophosphoramide mustard, a metabolite of ifosfamide with activity against murine tumours comparable to cyclophosphamide (Q36047370)

11 August 2017

Isophosphoramide mustard, a metabolite of ifosfamide with activity against murine tumours comparable to cyclophosphamide (English)

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11 August 2017

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R F Struck

1

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11 August 2017

D J Dykes

2

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11 August 2017

T H Corbett

3

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11 August 2017

W J Suling

4

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11 August 2017

M W Trader

5

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11 August 2017

language of work or name

English

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publication date

1 January 1983

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British Journal of Cancer

11 August 2017

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11 August 2017

47

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11 August 2017

1

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11 August 2017

15-26

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https://scigraph.springernature.com/pub.10.1038/bjc.1983.2

11 August 2017

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cites work

Cyclophosphamide (NSC-26271)-related phosphoramide mustards- recent advances and historical perspective

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2011256

Alkylating properties of phosphoramide mustard

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2011256

Methods for detecting carcinogens and mutagens with the Salmonella/mammalian-microsome mutagenicity test

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2011256

Effect of phenobarbital on plasma levels of cyclophosphamide and its metabolites in the mouse

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2011256

Cyclophosphamide cystitis—Identification of acrolein as the causative agent

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2011256

Cytotoxic activity of alkylating agents in the presence of centrophenoxine and its hydrolysis products

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2011256

The enzymatic basis of the selective action of cyclophosphamide

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2011256

Acrolein, the causative factor of urotoxic side-effects of cyclophosphamide, ifosfamide, trofosfamide and sufosfamide

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2011256

Controlled clinical studies with an antidote against the urotoxicity of oxazaphosphorines: preliminary results

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2011256

Design and evaluation of combination chemotherapy trials in experimental animal tumor systems

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2011256

Permeability of N,N-bis(2-chloroethyl)-diamido-phosphoric-acid into tumor cells (author's transl)

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2011256

Prevention of isophosphamide-induced urothelial toxicity with 2-mercaptoethane sulphonate sodium (mesnum) in patients with advanced carcinoma

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2011256

[New nitrogen mustard phosphamide esters and their cytostatic activity]

23 September 2018

1 reference

12 December 2020

Alkylans-alkylandum reactions. 4. 2-chlorethylamine and phosphamide compounds as alkylants

1 reference

12 December 2020

Metabolism of cyclophosphamide by sheep

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12 December 2020

Isophosphamide as a new acrolein-producing antineoplastic isomer of cyclophosphamide

1 reference

12 December 2020

Metabolism of iphosphamide (2-(2-chloroethylamino)-3-(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide) and production of a toxic iphosphamide metabolite

1 reference

12 December 2020

Synthesis and metabolic behavior of the suggested active species of isophosphamide having cytostatic activity

1 reference

12 December 2020

Isolation and mass spectral identification of blood metabolities of cyclophosphamide: Evidence for phosphoramide mustard as the biologically active metabolite

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12 December 2020

Studies on the metabolism of isopnosphamide (NSC-109724) in man

1 reference

12 December 2020

Evaluation of single agents and combinations of chemotherapeutic agents in mouse colon carcinomas

1 reference

12 December 2020

Quantitation by gas chromatography-chemical ionization mass spectrometry of cyclophosphamide, phosphoramide mustard, and nornitrogen mustard in the plasma and urine of patients receiving cyclophosphamide therapy

1 reference

12 December 2020

Denaturation of cytochrome P-450 by cyclophosphamide metabolites

1 reference

12 December 2020

Kinetics of cyclophosphamide biotransformation in vivo

1 reference

12 December 2020

The embryotoxicity of the cyclophosphamide metabolite acrolein in rabbits, tested in vivo by i.v. injection and by the yolk-sac method

1 reference

12 December 2020

Differential cytotoxicity and DNA cross-linking produced by polymeric and monomeric activated analogues of cyclophosphamide in mouse L1210 leukemia cells

1 reference

12 December 2020

Ifosfamide: a weekly dose fractionated schedule in bronchogenic carcinoma

1 reference

12 December 2020

Identifiers

DOI

10.1038/BJC.1983.2

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11 August 2017

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11 August 2017

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