Lipid homeostasis and apolipoprotein E in the development and progression of Alzheimer's disease (Q36044934)

11 August 2017

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title

Lipid homeostasis and apolipoprotein E in the development and progression of Alzheimer's disease (English)

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11 August 2017

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Roger M Lane

1

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PubMed ID

15716586

11 August 2017

Martin R Farlow

series ordinal

2

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11 August 2017

16 February 2005

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Journal of Lipid Research

11 August 2017

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11 August 2017

46

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11 August 2017

949-968

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11 August 2017

5

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Dietary fat intake and the risk of incident dementia in the Rotterdam Study

11 August 2017

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Dietary lipids in the aetiology of Alzheimer's disease: implications for therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

High carbohydrate diets and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Redox-active iron mediates amyloid-beta toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Increased brain beta-amyloid load, phosphorylated tau, and risk of Alzheimer disease associated with an intronic CYP46 polymorphism

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Cholesterol-dependent modulation of dendrite outgrowth and microtubule stability in cultured neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Oxidative regulation of fatty acid-induced tau polymerization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Neuronal membrane cholesterol loss enhances amyloid peptide generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Effects of dietary polyunsaturated fatty acids on neuronal function

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

A new role for apolipoprotein E: modulating transport of polyunsaturated phospholipid molecular species in synaptic plasma membranes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Docosahexaenoic acid protects from dendritic pathology in an Alzheimer's disease mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Docosahexaenoic acid provides protection from impairment of learning ability in Alzheimer's disease model rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Glucose transport and utilization are altered in the brain of rats deficient in n-3 polyunsaturated fatty acids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Functional brain abnormalities in young adults at genetic risk for late-onset Alzheimer's dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Prostaglandins, Arachidonic Acid, and Inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Consumption of fish and n-3 fatty acids and risk of incident Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Fish, meat, and risk of dementia: cohort study

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Polyunsaturated fatty acids and cerebral function: focus on monoaminergic neurotransmission.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Dietary docosahexaenoic acid increases cerebral acetylcholine levels and improves passive avoidance performance in stroke-prone spontaneously hypertensive rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Effect of a diet-induced n-3 PUFA depletion on cholinergic parameters in the rat hippocampus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Dietary n-3 fatty acid deficiency decreases nerve growth factor content in rat hippocampus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Effect of the long-term feeding of dietary lipids on the learning ability, fatty acid composition of brain stem phospholipids and synaptic membrane fluidity in adult mice: a comparison of sardine oil diet with palm oil diet.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Neuroprotective effect of eicosapentaenoic acid in hippocampus of rats exposed to gamma-irradiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Dietary docosahexaenoic acid dose not promote lipid peroxidation in rat tissue to the extent expected from peroxidizability index of the lipids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Influence of docosahexaenoic acid on cerebral lipid peroxide level in aged rats with and without hypercholesterolemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Neuroprotective effect of developmental docosahexaenoic acid supplement against excitotoxic brain damage in infant rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Effect of long-term administration of ethyl eicosapentate (EPA-E) on local cerebral blood flow and glucose utilization in stroke-prone spontaneously hypertensive rats (SHRSP).

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

The chronic administration of docosahexaenoic acid reduces the spatial cognitive deficit following transient forebrain ischemia in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Essential fatty acids preparation (SR-3) improves Alzheimer's patients quality of life.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Chronic administration of docosahexaenoic acid improves reference memory-related learning ability in young rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Chronic administration of docosahexaenoic acid improves the performance of radial arm maze task in aged rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Apolipoprotein E (APOE) allele distribution in the world. Is APOE*4 a 'thrifty' allele?

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Decrease of lipoprotein lipase activity in skeletal muscle in man during a short-term carbohydrate-rich dietary regime. With special reference to HDL-cholesterol, apolipoprotein and insulin concentrations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Effect of apolipoprotein E3/4 phenotype on postprandial triglycerides and retinyl palmitate metabolism in plasma from hyperlipidemic subjects in Japan

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Effect of apolipoprotein E4 allele on plasma LDL cholesterol response to diet therapy in type 2 diabetic patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

The metabolic syndrome and aging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Brain cholesterol: long secret life behind a barrier.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Reduction in levels of 24S-hydroxycholesterol by statin treatment in patients with Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Plasma 24S-hydroxycholesterol: a peripheral indicator of neuronal degeneration and potential state marker for Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Continual remodeling of postsynaptic density and its regulation by synaptic activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Differential effects of apolipoproteins E3 and E4 on neuronal growth in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

CNS synaptogenesis promoted by glia-derived cholesterol

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Evidence for changes in the Alzheimer's disease brain cortical membrane structure mediated by cholesterol.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Axonal transport of amyloid precursor protein is mediated by direct binding to the kinesin light chain subunit of kinesin-I

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Disruption of axonal transport and neuronal viability by amyloid precursor protein mutations in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Kinesin-mediated axonal transport of a membrane compartment containing beta-secretase and presenilin-1 requires APP

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Abnormal glutamate transport function in mutant amyloid precursor protein transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Neurotrophins: roles in neuronal development and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Cholesterol-dependent modulation of tau phosphorylation in cultured neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Cholesterol and pathological processes in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Beta-VLDL protects against A beta(1-42) and apoE toxicity in human SH-SY5Y neuroblastoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Amyloid beta-protein affects cholesterol metabolism in cultured neurons: implications for pivotal role of cholesterol in the amyloid cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Review: Alzheimer's amyloid beta-peptide-associated free radical oxidative stress and neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

AMPA receptors are the major mediators of excitotoxic death in mature oligodendrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Influence of apolipoprotein E epsilon4 genotype on brain tissue integrity in relapsing-remitting multiple sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Curvilinear regression course of human brain lipid composition changes with age.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Recent advances in brain cholesterol dynamics: transport, domains, and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Abeta42-peptide assembly on lipid bilayers

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Effects of high cholesterol diet on gliosis in apolipoprotein E knockout mice. Implications for Alzheimer's disease and stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Lipid rafts play an important role in A beta biogenesis by regulating the beta-secretase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Changes in Apolipoprotein E Expression in Response to Dietary and Pharmacological Modulation of Cholesterol

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Brain region-dependent increases in beta-amyloid and apolipoprotein E levels in hypercholesterolemic rabbits

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Cholesterol in neurologic disorders of the elderly: stroke and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Serum total cholesterol, apolipoprotein E epsilon 4 allele, and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Iron, atherosclerosis, and neurodegeneration: a key role for cholesterol in promoting iron-dependent oxidative damage?

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Mild hypercholesterolemia is an early risk factor for the development of Alzheimer amyloid pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Apolipoprotein E epsilon4 allele, elevated midlife total cholesterol level, and high midlife systolic blood pressure are independent risk factors for late-life Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Decreased prevalence of Alzheimer disease associated with 3-hydroxy-3-methyglutaryl coenzyme A reductase inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Use of lipid-lowering agents, indication bias, and the risk of dementia in community-dwelling elderly people.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Statin therapy and risk of dementia in the elderly: a community-based prospective cohort study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Treatment with simvastatin in normocholesterolemic patients with Alzheimer's disease: A 26-week randomized, placebo-controlled, double-blind trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Cholesterol, statins and dementia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

The APOE locus and the pharmacogenetics of lipid response

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

3-Hydroxy-3-methylglutaryl CoA reductase inhibitors reduce serum triglyceride levels through modulation of apolipoprotein C-III and lipoprotein lipase

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors attenuate beta-amyloid-induced microglial inflammatory responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Secretion of apolipoprotein E by brain glia requires protein prenylation and is suppressed by statins

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Modulation of statin-activated shedding of Alzheimer APP ectodomain by ROCK

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Gene regulation and DNA damage in the ageing human brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Effect of non-steroidal anti-inflammatory drugs on risk of Alzheimer's disease: systematic review and meta-analysis of observational studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

The essentiality of long chain n-3 fatty acids in relation to development and function of the brain and retina.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Evidence that amyloid beta-peptide-induced lipid peroxidation and its sequelae in Alzheimer's disease brain contribute to neuronal death

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

The glial glutamate transporter, GLT-1, is oxidatively modified by 4-hydroxy-2-nonenal in the Alzheimer's disease brain: the role of Abeta1-42.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Deficient glutamate transport is associated with neurodegeneration in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Neuronal and glial calcium signaling in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Gene-diet interactions in brain aging and neurodegenerative disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Motor and cognitive deficits in apolipoprotein E-deficient mice after closed head injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Apolipoprotein E deficiency worsens outcome from global cerebral ischemia in the mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Brains of aged apolipoprotein E-deficient mice have increased levels of F2-isoprostanes, in vivo markers of lipid peroxidation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Microglial activation by Alzheimer amyloid precursor protein and modulation by apolipoprotein E.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Apolipoprotein E: a major piece in the Alzheimer's disease puzzle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Apolipoprotein E4 forms a molten globule. A potential basis for its association with disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Generation of a recombinant apolipoprotein E variant with improved biological functions: hydrophobic residues (LEU-261, TRP-264, PHE-265, LEU-268, VAL-269) of apoE can account for the apoE-induced hypertriglyceridemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Cholesterol synthesis and lipoprotein reuptake during synaptic remodelling in hippocampus in adult rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Apolipoprotein E: diversity of cellular origins, structural and biophysical properties, and effects in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Cholesterol synthesis is down-regulated during regeneration of peripheral nerve

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Comparison of the stabilities and unfolding pathways of human apolipoprotein E isoforms by differential scanning calorimetry and circular dichroism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Carboxyl-terminal-truncated apolipoprotein E4 causes Alzheimer's disease-like neurodegeneration and behavioral deficits in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Deficiency of ABCA1 impairs apolipoprotein E metabolism in brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

ABCA1 is required for normal central nervous system ApoE levels and for lipidation of astrocyte-secreted apoE.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

APOE genotype predicts when--not whether--one is predisposed to develop Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Association between apolipoprotein E epsilon4 and the rate of cognitive decline in community-dwelling elderly individuals with and without dementia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

APOE-epsilon4 count predicts age when prevalence of AD increases, then declines: the Cache County Study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Patterns of brain activation in people at risk for Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Apolipoprotein E epsilon4 allele, AD pathology, and the clinical expression of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Cerebrovascular disease, the apolipoprotein e4 allele, and cognitive decline in a community-based study of elderly men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Midlife cardiovascular risk factors, ApoE, and cognitive decline in elderly male twins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

The role of APOE epsilon4 in modulating effects of other risk factors for cognitive decline in elderly persons

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Type 2 diabetes, APOE gene, and the risk for dementia and related pathologies: The Honolulu-Asia Aging Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Cholesterol and Tau Protein - Findings in Alzheimer’s and Niemann Pick C’s Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

ABCA1 modulates CSF cholesterol levels and influences the age at onset of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

The relationship between apolipoprotein E4 and lipid metabolism is impaired in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Distribution of reducible 4-hydroxynonenal adduct immunoreactivity in Alzheimer disease is associated with APOE genotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Reduced levels of antioxidants in brains of apolipoprotein E-deficient mice following closed head injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Increased levels of intracellular iron in the brains of ApoE-deficient mice with closed head injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Control of apolipoprotein E secretion by 25-hydroxycholesterol and proinflammatory cytokines in the human astrocytoma cell line CCF-STTG1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Genetic influences on age-related change in total cholesterol, low density lipoprotein-cholesterol, and triglyceride levels: longitudinal apolipoprotein E genotype effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Apolipoprotein E gene promoter polymorphisms in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Apolipoprotein E and the CNS response to injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Apolipoprotein E dose-dependent modulation of beta-amyloid deposition in a transgenic mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Association of apolipoprotein E genotype with brain levels of apolipoprotein E and apolipoprotein J (clusterin) in Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Alzheimer vaccine: amyloid-beta on trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

The levels of soluble amyloid beta in different high density lipoprotein subfractions distinguish Alzheimer's and normal aging cerebrospinal fluid: implication for brain cholesterol pathology?

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

ApoE and clusterin cooperatively suppress Abeta levels and deposition: evidence that ApoE regulates extracellular Abeta metabolism in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Association of human, rat, and rabbit apolipoprotein E with beta-amyloid

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Apolipoprotein E promotes astrocyte colocalization and degradation of deposited amyloid-beta peptides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Apolipoprotein E is essential for amyloid deposition in the APP(V717F) transgenic mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

A nontransgenic mouse model shows inducible amyloid-beta (Abeta) peptide deposition and elucidates the role of apolipoprotein E in the amyloid cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Apolipoprotein E associates with beta amyloid peptide of Alzheimer's disease to form novel monofibrils. Isoform apoE4 associates more efficiently than apoE3

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Differential effects of apolipoprotein E isoforms on metal-induced aggregation of A beta using physiological concentrations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Apolipoprotein E, amyloid, and Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

A dual role for apolipoprotein e in neuroinflammation: anti- and pro-inflammatory activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Astrogliosis and the ApoE genotype. an immunohistochemical study of postmortem human brain tissue.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Relationship between apoE4 allele and excitatory amino acid levels after traumatic brain injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Apolipoprotein E epsilon 4 allele is associated with deposition of amyloid beta-protein following head injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Interaction between hypertension, apoE, and cerebral white matter lesions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Regulation of the rat oligodendroglia cell line OLN-93 by antisense transfection of butyrylcholinesterase

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Acetylcholinesterase induces the expression of the beta-amyloid precursor protein in glia and activates glial cells in culture.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Regulation of beta-amyloid stimulated proinflammatory responses by peroxisome proliferator-activated receptor alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Lipopolysaccharide-induced-neuroinflammation increases intracellular accumulation of amyloid precursor protein and amyloid beta peptide in APPswe transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Chronic gliosis triggers Alzheimer's disease-like processing of amyloid precursor protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Intracellular accumulation of beta-amyloid(1-42) in neurons is facilitated by the alpha 7 nicotinic acetylcholine receptor in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Diet-induced changes in AChE activity after long-term exposure

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Apolipoprotein E4 allele as a predictor of cholinergic deficits and treatment outcome in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Does apolipoprotein E (Apo-E) genotype influence nicotinic receptor binding in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Genetics and visual attention: selective deficits in healthy adult carriers of the epsilon 4 allele of the apolipoprotein E gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

APOE genotype and survival in men and women with Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Hippocampal atrophy and apolipoprotein E genotype are independently associated with Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Impact of APOE in mild cognitive impairment

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Cerebral glucose metabolism, cerebrospinal fluid-beta-amyloid1-42 (CSF-Abeta42), tau and apolipoprotein E genotype in long-term rivastigmine and tacrine treated Alzheimer disease (AD) patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Acetylcholinesterase and its inhibition in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Differential qualitative responses to rivastigmine in APOE epsilon 4 carriers and noncarriers

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

APOE genotype: no influence on galantamine treatment efficacy nor on rate of decline in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Effects of acetylcholinesterase and butyrylcholinesterase on cell survival, neurite outgrowth, and voltage-dependent calcium currents of embryonic ventral mesencephalic neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Acetylcholinesterase accelerates assembly of amyloid-beta-peptides into Alzheimer's fibrils: possible role of the peripheral site of the enzyme.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Relationship between serum butyrylcholinesterase activity, hypertriglyceridaemia and insulin sensitivity in diabetes mellitus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Interrelationship between serum -lipoprotein and cholinesterase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Using meta-analysis to explain the diversity of results in genetic studies of late-onset Alzheimer's disease and to identify high-risk subgroups.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Regulation of attention and response to therapy in dementia by butyrylcholinesterase

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Rivastigmine superior to aspirin plus nimodipine in subcortical vascular dementia: an open, 16-month, comparative study

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Rivastigmine in vascular dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Acetylcholinesterase inhibitor ENA-713 protects against ischemia-induced decrease in pre- and postsynaptic cholinergic indices in the gerbil brain following transient ischemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Post-ischemic administration of the acetylcholinesterase inhibitor ENA-713 prevents delayed neuronal death in the gerbil hippocampus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Lipid rafts and signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Astrocyte heterogeneity: endogenous amino acid levels and release evoked by non-N-methyl-D-aspartate receptor agonists and by potassium-induced swelling in type-1 and type-2 astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

L-serine-mediated release of apolipoprotein E and lipids from microglial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Neuregulin induces GABAA receptor beta2 subunit expression in cultured rat cerebellar granule neurons by activating multiple signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Dimeric amyloid beta protein rapidly accumulates in lipid rafts followed by apolipoprotein E and phosphorylated tau accumulation in the Tg2576 mouse model of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Lack of apolipoprotein E dramatically reduces amyloid beta-peptide deposition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Human and murine ApoE markedly alters A beta metabolism before and after plaque formation in a mouse model of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Apolipoprotein E isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Functions of lipoprotein receptors in neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Caloric intake and the risk of Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Obesity modulates the association among APOE genotype, insulin, and glucose in men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Apolipoprotein E epsilon4 count affects age at onset of Alzheimer disease, but not lifetime susceptibility: The Cache County Study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Apolipoprotein E allele epsilon 4, dementia, and cognitive decline in a population sample.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Apolipoprotein E epsilon 4 allele and the lifetime risk of Alzheimer's disease. What physicians know, and what they should know.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Reduction of Serum Cholesterol and Hypercholesterolemic Atherosclerosis in Rabbits by Secoisolariciresinol Diglucoside Isolated From Flaxseed

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Cholesterol, Synaptic Function and Alzheimer’s Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Diet and oxidative stress: a novel synthesis of epidemiological data on Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

Evaluation of polymorphisms in the presenilin-1 gene and the butyrylcholinesterase gene as risk factors in sporadic Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400486-JLR200

10.1194/JLR.M400486-JLR200

21 January 2018

Identifiers

DOI

1 reference

11 August 2017

1 reference

PubMed ID

15716586