UDCA exerts beneficial effect on mitochondrial dysfunction in LRRK2(G2019S) carriers and in vivo. (Q36027872)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26253449%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

title

UDCA exerts beneficial effect on mitochondrial dysfunction in LRRK2(G2019S) carriers and in vivo (English)

1 reference

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21 February 2020

1

1 reference

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21 February 2020

Elliott CJH

5

1 reference

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21 February 2020

Oliver Bandmann

6

1 reference

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21 February 2020

author name string

Rebecca Furmston

2

1 reference

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21 February 2020

Gunnar Bronstad

3

1 reference

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21 February 2020

Jan Aasly

4

1 reference

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21 February 2020

language of work or name

English

0 references

publication date

7 August 2015

1 reference

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21 February 2020

1 reference

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21 February 2020

volume

85

1 reference

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21 February 2020

issue

10

1 reference

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21 February 2020

page(s)

846-852

1 reference

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Abnormal visual gain control in a Parkinson's disease model

21 February 2020

cites work

1 reference

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Does uncoupling protein 2 expression qualify as marker of disease status in LRRK2-associated Parkinson's disease?

2 October 2017

1 reference

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Ursocholanic acid rescues mitochondrial function in common forms of familial Parkinson's disease

2 October 2017

1 reference

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The PINK1-Parkin pathway promotes both mitophagy and selective respiratory chain turnover in vivo

2 October 2017

1 reference

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Interplay of LRRK2 with chaperone-mediated autophagy

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4560055

Dopaminergic expression of the Parkinsonian gene LRRK2-G2019S leads to non-autonomous visual neurodegeneration, accelerated by increased neural demands for energy.

2 October 2017

1 reference

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Pharmacological rescue of mitochondrial deficits in iPSC-derived neural cells from patients with familial Parkinson's disease

2 October 2017

1 reference

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G2019S leucine-rich repeat kinase 2 causes uncoupling protein-mediated mitochondrial depolarization

2 October 2017

1 reference

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Mechanisms of LRRK2-mediated neurodegeneration.

2 October 2017

1 reference

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LRRK2 regulates mitochondrial dynamics and function through direct interaction with DLP1

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4560055

Mitophagy: the latest problem for Parkinson's disease

2 October 2017

1 reference

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Inhibitors of leucine-rich repeat kinase-2 protect against models of Parkinson's disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4560055

Metabolomic profiling in LRRK2-related Parkinson's disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4560055

Parkin protects against LRRK2 G2019S mutant-induced dopaminergic neurodegeneration in Drosophila.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4560055

Mitochondrial function and morphology are impaired in parkin-mutant fibroblasts

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4560055

Phenotype, genotype, and worldwide genetic penetrance of LRRK2-associated Parkinson's disease: a case-control study

2 October 2017

1 reference

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Mitochondrial dysfunction, peroxidation damage and changes in glutathione metabolism in PARK6.

2 October 2017

1 reference

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Kinase activity of mutant LRRK2 mediates neuronal toxicity

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4560055

Kinase activity is required for the toxic effects of mutant LRRK2/dardarin

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4560055

Leucine-rich repeat kinase 2 (LRRK2) interacts with parkin, and mutant LRRK2 induces neuronal degeneration

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4560055

Mitochondrial impairment in patients with Parkinson disease with the G2019S mutation in LRRK2.

2 October 2017

1 reference

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Olfaction and imaging biomarkers in premotor LRRK2 G2019S-associated Parkinson disease.

11 July 2018

1 reference

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Tauroursodeoxycholic acid prevents MPTP-induced dopaminergic cell death in a mouse model of Parkinson's disease.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4560055

Safety, tolerability, and cerebrospinal fluid penetration of ursodeoxycholic Acid in patients with amyotrophic lateral sclerosis.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4560055

LRRK2G2019S as a Cause of Parkinson's Disease in North African Arabs

23 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26253449

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Primary biliary cirrhosis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26253449

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1212/WNL.0000000000001905

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26253449%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26253449%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

1 reference