Requirement for an initial signal from the membrane-proximal region of the interleukin 2 receptor gamma(c) chain for Janus kinase activation leading to T cell proliferation (Q36026082)

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English	Requirement for an initial signal from the membrane-proximal region of the interleukin 2 receptor gamma(c) chain for Janus kinase activation leading to T cell proliferation	scientific article

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scholarly article

1 reference

Europe PubMed Central

11 August 2017

Requirement for an initial signal from the membrane-proximal region of the interleukin 2 receptor gamma(c) chain for Janus kinase activation leading to T cell proliferation (English)

1 reference

Europe PubMed Central

11 August 2017

0 references

author name string

B H Nelson

1

1 reference

Europe PubMed Central

11 August 2017

B C McIntosh

2

1 reference

Europe PubMed Central

11 August 2017

L L Rosencrans

3

1 reference

Europe PubMed Central

11 August 2017

P D Greenberg

4

1 reference

Europe PubMed Central

11 August 2017

language of work or name

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publication date

1 March 1997

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Europe PubMed Central

11 August 2017

Proceedings of the National Academy of Sciences of the United States of America

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Europe PubMed Central

11 August 2017

94

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Europe PubMed Central

11 August 2017

1878-1883

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Europe PubMed Central

11 August 2017

5

1 reference

Europe PubMed Central

11 August 2017

An epidermal growth factor receptor/Jak2 tyrosine kinase domain chimera induces tyrosine phosphorylation of Stat5 and transduces a growth signal in hematopoietic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20011

2 October 2017

Different interleukin 2 receptor beta-chain tyrosines couple to at least two signaling pathways and synergistically mediate interleukin 2-induced proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20011

2 October 2017

Ligand-induced assembly and activation of the gamma interferon receptor in intact cells

1 reference

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2 October 2017

Dispensability of Jak1 tyrosine kinase for interleukin-2-induced cell growth signaling in a human T cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20011

2 October 2017

Evidence for a role for the phosphotyrosine-binding domain of Shc in interleukin 2 signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20011

2 October 2017

PTP1D is a positive regulator of the prolactin signal leading to beta-casein promoter activation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20011

2 October 2017

The molecular role of the common gamma c subunit in signal transduction reveals functional asymmetry within multimeric cytokine receptor complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20011

2 October 2017

A membrane-proximal region of the interleukin-2 receptor gamma c chain sufficient for Jak kinase activation and induction of proliferation in T cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20011

2 October 2017

The interleukin-2 receptor gamma chain maps to Xq13.1 and is mutated in X-linked severe combined immunodeficiency, SCIDX1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20011

2 October 2017

The adapter protein Shc interacts with the interleukin-2 (IL-2) receptor upon IL-2 stimulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20011

2 October 2017

Interleukin-2 receptor gamma chain: a functional component of the interleukin-4 receptor

1 reference

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2 October 2017

Interleukin-2 receptor gamma chain: a functional component of the interleukin-7 receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20011

2 October 2017

Sharing of the interleukin-2 (IL-2) receptor gamma chain between receptors for IL-2 and IL-4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20011

2 October 2017

Functional participation of the IL-2 receptor gamma chain in IL-7 receptor complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20011

2 October 2017

Interleukin 2-induced activation of JAK3: possible involvement in signal transduction for c-myc induction and cell proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20011

2 October 2017

Physical association of JAK1 and JAK2 tyrosine kinases with the interleukin 2 receptor beta and gamma chains.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20011

2 October 2017

Utilization of the beta and gamma chains of the IL-2 receptor by the novel cytokine IL-15

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20011

2 October 2017

Involvement of the Jak-3 Janus kinase in signalling by interleukins 2 and 4 in lymphoid and myeloid cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20011

2 October 2017

JAK2 associates with the beta c chain of the receptor for granulocyte-macrophage colony-stimulating factor, and its activation requires the membrane-proximal region

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20011

2 October 2017

Functional activation of Jak1 and Jak3 by selective association with IL-2 receptor subunits

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20011

2 October 2017

Interaction of IL-2R beta and gamma c chains with Jak1 and Jak3: implications for XSCID and XCID

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20011

2 October 2017

Prevention of T cell anergy by signaling through the gamma c chain of the IL-2 receptor

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20011

2 October 2017

Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20011

2 October 2017

Dimerization of cell surface receptors in signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20011

2 October 2017

Lymphoid development in mice with a targeted deletion of the interleukin 2 receptor gamma chain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20011

2 October 2017

Activation of Stat5 by interleukin 2 requires a carboxyl-terminal region of the interleukin 2 receptor beta chain but is not essential for the proliferative signal transmission

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20011

2 October 2017

Signaling mechanisms through cytokine receptors that share signal transducing receptor components

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20011

2 October 2017

Cytokine signaling through nonreceptor protein tyrosine kinases

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20011

2 October 2017

Defective lymphoid development in mice lacking expression of the common cytokine receptor gamma chain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20011

2 October 2017

Reconstitution of functional interleukin 2 receptor complexes on fibroblastoid cells: involvement of the cytoplasmic domain of the gamma chain in two distinct signaling pathways

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20011

2 October 2017

Growth signal transduction by the human interleukin-2 receptor requires cytoplasmic tyrosines of the beta chain and non-tyrosine residues of the gamma c chain.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20011

2 October 2017

Mutations of Jak-3 gene in patients with autosomal severe combined immune deficiency (SCID)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20011

2 October 2017

Protein tyrosine kinase Syk is associated with and activated by the IL-2 receptor: possible link with the c-myc induction pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20011

2 October 2017

Critical role of the interleukin 2 (IL-2) receptor gamma-chain-associated Jak3 in the IL-2-induced c-fos and c-myc, but not bcl-2, gene induction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20011

2 October 2017

Cytokine receptor signalling

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20011

2 October 2017

Interleukin 2 signaling involves the phosphorylation of Stat proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20011

2 October 2017

Signaling through the interleukin 2 receptor beta chain activates a STAT-5-like DNA-binding activity

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20011

2 October 2017

Signal transduction by a CD16/CD7/Jak2 fusion protein

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2 October 2017

Characterization of critical residues in the cytoplasmic domain of the human interleukin-5 receptor alpha chain required for growth signal transduction

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Regions of the JAK2 tyrosine kinase required for coupling to the growth hormone receptor

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2 October 2017

Analysis of interleukin-2-dependent signal transduction through the Shc/Grb2 adapter pathway. Interleukin-2-dependent mitogenesis does not require Shc phosphorylation or receptor association

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2 October 2017

Mutation of Jak3 in a patient with SCID: essential role of Jak3 in lymphoid development.

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2 October 2017

Interaction of the IL-2 receptor with the src-family kinase p56lck: identification of novel intermolecular association

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2 October 2017

Cloning of the gamma chain of the human IL-2 receptor

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2 October 2017

Interleukin-2 receptor gamma chain mutation results in X-linked severe combined immunodeficiency in humans

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11 July 2018

Heterodimerization of the IL-2 receptor beta- and gamma-chain cytoplasmic domains is required for signalling

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11 July 2018

Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine.

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11 July 2018

Cytoplasmic domains of the interleukin-2 receptor beta and gamma chains mediate the signal for T-cell proliferation.

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11 July 2018

A restricted cytoplasmic region of IL-2 receptor beta chain is essential for growth signal transduction but not for ligand binding and internalization

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11 July 2018

Interleukin 2 (IL-2)-induced tyrosine phosphorylation of IL-2 receptor p75

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11 July 2018

The role of shared receptor motifs and common Stat proteins in the generation of cytokine pleiotropy and redundancy by IL-2, IL-4, IL-7, IL-13, and IL-15.

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21 January 2018

Developmental defects of lymphoid cells in Jak3 kinase-deficient mice.

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https://api.crossref.org/works/10.1073%2FPNAS.94.5.1878

21 January 2018

Mammalian SH2-containing protein tyrosine phosphatases.

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21 January 2018

Defective lymphoid development in mice lacking Jak3

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21 January 2018

Defects in B lymphocyte maturation and T lymphocyte activation in mice lacking Jak3

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21 January 2018

IL-2-induced signal transduction: involvement of tyrosine kinase and IL-2 receptor gamma chain

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12 December 2020

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10.1073/PNAS.94.5.1878

1 reference

Europe PubMed Central

11 August 2017

1997PNAS...94.1878N

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1 reference

Europe PubMed Central

11 August 2017

1 reference

Europe PubMed Central

11 August 2017

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