Modulation of p-glycoprotein transport function at the blood-brain barrier (Q36021258)

11 August 2017

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title

Modulation of p-glycoprotein transport function at the blood-brain barrier (English)

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11 August 2017

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4

David S Miller

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11 August 2017

3

Gert Fricker

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11 August 2017

Björn Bauer

1

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PubMed ID

15673560

11 August 2017

Anika M S Hartz

series ordinal

2

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11 August 2017

1 February 2005

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Experimental Biology and Medicine

11 August 2017

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11 August 2017

230

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11 August 2017

2

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11 August 2017

118-127

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Plasma membrane localization of multidrug resistance-associated protein homologs in brain capillary endothelial cells

11 August 2017

1 reference

https://api.crossref.org/works/10.1177%2F153537020523000206

Evaluation of the immortalised mouse brain capillary endothelial cell line, b.End3, as an in vitro blood-brain barrier model for drug uptake and transport studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020523000206

21 January 2018

Bile salt transporters

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https://api.crossref.org/works/10.1177%2F153537020523000206

Multidrug resistance protein 1 protects the choroid plexus epithelium and contributes to the blood-cerebrospinal fluid barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020523000206

Localization of the organic anion transporting polypeptide 2 (Oatp2) in capillary endothelium and choroid plexus epithelium of rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020523000206

Role of blood-brain barrier organic anion transporter 3 (OAT3) in the efflux of indoxyl sulfate, a uremic toxin: its involvement in neurotransmitter metabolite clearance from the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020523000206

Biochemical, cellular, and pharmacological aspects of the multidrug transporter

21 January 2018

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https://api.crossref.org/works/10.1177%2F153537020523000206

P-glycoprotein and multidrug resistance

21 January 2018

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https://api.crossref.org/works/10.1177%2F153537020523000206

Crystal structure of the ATP-binding subunit of an ABC transporter

21 January 2018

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https://api.crossref.org/works/10.1177%2F153537020523000206

Importance of P-glycoprotein at blood-tissue barriers

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020523000206

A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020523000206

Immunohistochemical localization in normal tissues of different epitopes in the multidrug transport protein P170: evidence for localization in brain capillaries and crossreactivity of one antibody with a muscle protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020523000206

Expression of the multidrug resistance gene product (P-glycoprotein) in human normal and tumor tissues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020523000206

Structural analysis of the mouse mdr1a (P-glycoprotein) promoter reveals the basis for differential transcript heterogeneity in multidrug-resistant J774.2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020523000206

Structure and expression of the human MDR (P-glycoprotein) gene family

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020523000206

Homozygous disruption of the murine mdr2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020523000206

Sequence of mdr3 cDNA encoding a human P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020523000206

Phospholipid flippase activity of the reconstituted P-glycoprotein multidrug transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020523000206

Multiple physiological functions for multidrug transporter P-glycoprotein?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020523000206

Volume-regulated chloride channels associated with the human multidrug-resistance P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020523000206

Multidrug resistance (MDR1) P-glycoprotein enhances esterification of plasma membrane cholesterol

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020523000206

Cytokine regulation of P-glycoprotein

21 January 2018

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https://api.crossref.org/works/10.1177%2F153537020523000206

P-glycoprotein in autoimmune diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020523000206

ABC transporters and the blood-brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020523000206

P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020523000206

Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020523000206

Ivermectin sensitivity in collies is associated with a deletion mutation of the mdr1 gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020523000206

Pharmacogenetics of MDR1 and its impact on the pharmacokinetics and pharmacodynamics of drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020523000206

Improved penetration of docetaxel into the brain by co-administration of inhibitors of P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020523000206

Transport of paclitaxel (Taxol) across the blood-brain barrier in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020523000206

Diagnosis and management of brain metastases

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020523000206

New strategy developments in brain tumor therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020523000206

Signalling pathways influencing basal and H2O2‐induced P‐glycoprotein expression in endothelial cells derived from the blood–brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020523000206

Puromycin selectively increases mdr1a expression in immortalized rat brain endothelial cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020523000206

Trafficking of canalicular ABC transporters in hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020523000206

Rapid regulation of P-glycoprotein at the blood-brain barrier by endothelin-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020523000206

Alkylglycerol opening of the blood-brain barrier to small and large fluorescence markers in normal and C6 glioma-bearing rats and isolated rat brain capillaries

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020523000206

Drug targeting. Breaking down barriers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020523000206

Outwitting the blood-brain barrier for therapeutic purposes: osmotic opening and other means

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020523000206

Role of NO in endothelin-regulated drug transport in the renal proximal tubule

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020523000206

Xenobiotic export pumps, endothelin signaling, and tubular nephrotoxicants--a case of molecular hijacking

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020523000206

New invMED1 element cis-activates human multidrug-related MDR1 and MVP genes, involving the LRP130 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020523000206

Transcriptional regulators of the human multidrug resistance 1 gene: recent views

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020523000206

Nuclear receptor response elements mediate induction of intestinal MDR1 by rifampin

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020523000206

An orphan nuclear receptor activated by pregnanes defines a novel steroid signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020523000206

The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020523000206

Promiscuous regulator of xenobiotic removal

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020523000206

Genetic profiling defines the xenobiotic gene network controlled by the nuclear receptor pregnane X receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020523000206

Activators of the rat pregnane X receptor differentially modulate hepatic and intestinal gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020523000206

Induction of ABCC3 (MRP3) by pregnane X receptor activators

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020523000206

The pregnane X receptor: a promiscuous xenobiotic receptor that has diverged during evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020523000206

Overexpression of multiple drug resistance genes in endothelial cells from patients with refractory epilepsy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020523000206

Ritonavir and dexamethasone induce expression of CYP3A and P-glycoprotein in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020523000206

Molecular aspects of bile formation and cholestasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020523000206

Suppression of drug-metabolizing enzymes and efflux transporters in the intestine of endotoxin-treated rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020523000206

Inflammatory cytokines, but not bile acids, regulate expression of murine hepatic anion transporters in endotoxemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020523000206

Repression of farnesoid X receptor during the acute phase response

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020523000206

Downregulation of mdr1a expression in the brain and liver during CNS inflammation alters the in vivo disposition of digoxin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020523000206

Influence of tumor necrosis factor-alpha on the expression and function of P-glycoprotein in an immortalised rat brain capillary endothelial cell line, GPNT.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020523000206

Evaluation of the role of P-glycoprotein in inflammation induced blood-brain barrier damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020523000206

Up-regulation of multidrug resistance P-glycoprotein via nuclear factor-kappaB activation protects kidney proximal tubule cells from cadmium- and reactive oxygen species-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020523000206

P-glycoprotein expression in rat brain endothelial cells: evidence for regulation by transient oxidative stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020523000206

10.1177/153537020523000206

21 January 2018

Identifiers

DOI

1 reference

11 August 2017

1 reference

PubMed ID

15673560