A mixed-charge pair in human interleukin 4 dominates high-affinity interaction with the receptor alpha chain (Q36019141)

11 August 2017

A mixed-charge pair in human interleukin 4 dominates high-affinity interaction with the receptor alpha chain (English)

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11 August 2017

Wang Y

1

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11 August 2017

Shen BJ

series ordinal

2

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11 August 2017

Sebald W

series ordinal

3

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11 August 2017

language of work or name

English

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publication date

1 March 1997

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Proceedings of the National Academy of Sciences of the United States of America

11 August 2017

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11 August 2017

94

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11 August 2017

5

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11 August 2017

1657-1662

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A murine interleukin-4 antagonistic mutant protein completely inhibits interleukin-4-induced cell proliferation, differentiation, and signal transduction

11 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19972

Principles of protein-protein interactions

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19972

Binding in the growth hormone receptor complex

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19972

Mechanism and regulation of immunoglobulin isotype switching.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19972

Interleukin-2 receptor gamma chain: a functional component of the interleukin-4 receptor

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19972

Sharing of the interleukin-2 (IL-2) receptor gamma chain between receptors for IL-2 and IL-4

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19972

Two distinct functional sites of human interleukin 4 are identified by variants impaired in either receptor binding or receptor activation.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19972

Aspects of receptor binding and signalling of interleukin-4 investigated by site-directed mutagenesis and NMR spectroscopy

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19972

Novel fundamental approaches to intervening in IgE-mediated allergic diseases

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19972

Lymphokine production by human T cells in disease states

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19972

Lymphocyte responses and cytokines

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19972

Dimerization of cell surface receptors in signal transduction

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19972

Human interleukin-4 and variant R88Q: phasing X-ray diffraction data by molecular replacement using X-ray and nuclear magnetic resonance models

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19972

A hot spot of binding energy in a hormone-receptor interface

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19972

The interleukin-2 and interleukin-4 receptors studied by molecular modelling

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19972

Structural design and molecular evolution of a cytokine receptor superfamily

2 October 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19972

2 October 2017

https://api.crossref.org/works/10.1073%2FPNAS.94.5.1657

Interleukin-4: a prototypic immunoregulatory lymphokine

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19972

Three-dimensional solution structure of human interleukin-4 by multidimensional heteronuclear magnetic resonance spectroscopy

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19972

Human interleukin 4. The solution structure of a four-helix bundle protein

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19972

The interleukin-4 receptor: structure, function, and signal transduction

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19972

Kinetics of protein-protein association explained by Brownian dynamics computer simulation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19972

Human growth hormone and extracellular domain of its receptor: crystal structure of the complex

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19972

Crystal structure of recombinant human interleukin-4

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19972

Conversion of human interleukin-4 into a high affinity antagonist by a single amino acid replacement

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19972

Energetics of protein-protein interactions: analysis of the barnase-barstar interface by single mutations and double mutant cycles.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19972

Receptor binding properties of four-helix-bundle growth factors deduced from electrostatic analysis.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19972

Structural comparisons among the short-chain helical cytokines

23 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.94.5.1657

A model of the complex between interleukin-4 and its receptors

21 January 2018

1 reference

12 December 2020

Crystal structure of human recombinant interleukin-4 at 2.25 A resolution

1 reference

12 December 2020

Immunochemical mapping of domains in human interleukin 4 recognized by neutralizing monoclonal antibodies

1 reference

12 December 2020

Comparison of a structural and a functional epitope

1 reference

12 December 2020

Neutralizing monoclonal antibodies define two different functional sites in human interleukin-4

1 reference

12 December 2020

NIH conference. Asthma

1 reference

12 December 2020

An antagonistic mutant of interleukin-4 fails to recruit gamma c into the receptor complex. Characterization by specific crosslinking

1 reference

12 December 2020

Rapid, electrostatically assisted association of proteins

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.94.5.1657

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11 August 2017

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11 August 2017

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