Asymmetry in the homodimeric ABC transporter MsbA recognized by a DARPin (Q36016933)

11 August 2017

Asymmetry in the homodimeric ABC transporter MsbA recognized by a DARPin (English)

1 reference

11 August 2017

Anshumali Mittal

1

1 reference

11 August 2017

Simon Böhm

2

1 reference

11 August 2017

Markus G Grütter

3

1 reference

11 August 2017

Enrica Bordignon

4

1 reference

11 August 2017

Markus A Seeger

5

1 reference

11 August 2017

language of work or name

English

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publication date

20 April 2012

1 reference

Journal of Biological Chemistry

11 August 2017

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11 August 2017

287

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11 August 2017

24

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11 August 2017

20395-20406

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ABC transporters, mechanisms and biology: an overview

11 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370220

Conformational analysis of human ATP-binding cassette transporter ABCB1 in lipid nanodiscs and inhibition by the antibodies MRK16 and UIC2.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370220

Designed ankyrin repeat protein binders for the crystallization of AcrB: plasticity of the dominant interface

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370220

Rotamer libraries of spin labelled cysteines for protein studies

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370220

Structural Basis for Negative Cooperativity in Growth Factor Binding to an EGF Receptor

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370220

Asymmetric switching in a homodimeric ABC transporter: a simulation study

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370220

Alternating access of the putative substrate-binding chamber in the ABC transporter MsbA.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370220

Conformational cycle of the ABC transporter MsbA in liposomes: detailed analysis using double electron-electron resonance spectroscopy.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370220

Engineering of recombinant crystallization chaperones

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370220

Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370220

The mechanism of ABC transporters: general lessons from structural and functional studies of an antigenic peptide transporter.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370220

Chaperone-assisted crystallography with DARPins

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370220

Flexibility in the ABC transporter MsbA: Alternating access with a twist

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370220

Conformational motion of the ABC transporter MsbA induced by ATP hydrolysis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370220

Ribosome display: selecting and evolving proteins in vitro that specifically bind to a target

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370220

Structure of the multidrug ABC transporter Sav1866 from Staphylococcus aureus in complex with AMP-PNP

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370220

Drug export pathway of multidrug exporter AcrB revealed by DARPin inhibitors

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370220

Structure of a bacterial multidrug ABC transporter

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370220

Structure of the KvAP voltage-dependent K+ channel and its dependence on the lipid membrane

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370220

Drug-lipid A interactions on the Escherichia coli ABC transporter MsbA.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370220

Sane in the membrane: designing systems to modulate membrane proteins

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370220

A pedestrian guide to membrane protein crystallization

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370220

High-affinity binders selected from designed ankyrin repeat protein libraries

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370220

Designing repeat proteins: well-expressed, soluble and stable proteins from combinatorial libraries of consensus ankyrin repeat proteins.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370220

The ATP binding cassette multidrug transporter LmrA and lipid transporter MsbA have overlapping substrate specificities

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370220

Designed to be stable: crystal structure of a consensus ankyrin repeat protein

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370220

Dimer formation drives the activation of the cell death protease caspase 9

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370220

Function of Escherichia coli MsbA, an essential ABC family transporter, in lipid A and phospholipid biosynthesis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370220

Multidrug resistance mediated by a bacterial homolog of the human multidrug transporter MDR1.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370220

Mutational analysis and properties of the msbA gene of Escherichia coli, coding for an essential ABC family transporter

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370220

The catalytic cycle of P-glycoprotein

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370220

P-glycoprotein is stably inhibited by vanadate-induced trapping of nucleotide at a single catalytic site

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370220

Characterization of the E506Q and H537A dysfunctional mutants in the E. coli ABC transporter MsbA.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370220

Mapping daunorubicin-binding Sites in the ATP-binding cassette transporter MsbA using site-specific quenching by spin labels

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370220

Cryogenic Q-band (35GHz) probehead featuring large excitation microwave fields for pulse and continuous wave electron paramagnetic resonance spectroscopy: performance and applications

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370220

A structural analysis of asymmetry required for catalytic activity of an ABC-ATPase domain dimer

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370220

Dissection of the conformational cycle of the multidrug/lipidA ABC exporter MsbA.

11 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.359794

The conserved glutamate residue adjacent to the Walker-B motif is the catalytic base for ATP hydrolysis in the ATP-binding cassette transporter BmrA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.359794

Crystal structures of a multidrug transporter reveal a functionally rotating mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.359794

Structural asymmetry of AcrB trimer suggests a peristaltic pump mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.359794

Determining the dimensions of the drug-binding domain of human P-glycoprotein using thiol cross-linking compounds as molecular rulers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.359794

On the energy-dependence of Hoechst 33342 transport by the ABC transporter LmrA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.359794

Membrane reconstitution of ABC transporters and assays of translocator function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.359794

DeerAnalysis2006—a comprehensive software package for analyzing pulsed ELDOR data

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.359794

Functional characterization of Escherichia coli MsbA: interaction with nucleotides and substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.359794

Three-spin correlations in double electron-electron resonance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.359794

In vitro selection and characterization of DARPins and Fab fragments for the co-crystallization of membrane proteins: The Na(+)-citrate symporter CitS as an example

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370220

ATP hydrolysis at one of the two sites in ABC transporters initiates transport related conformational transitions

23 September 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.359794

Dead-Time Free Measurement of Dipole–Dipole Interactions between Electron Spins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.359794

21 January 2018

Identifiers

DOI

10.1074/JBC.M112.359794

1 reference

11 August 2017

1 reference

11 August 2017

1 reference