Evolving concepts of liver fibrogenesis provide new diagnostic and therapeutic options (Q36014644)

11 August 2017

1 reference

title

Evolving concepts of liver fibrogenesis provide new diagnostic and therapeutic options (English)

1 reference

11 August 2017

Ralf Weiskirchen

2

0 references

author name string

Olav A Gressner

series ordinal

1

1 reference

PMCID

1994681

11 August 2017

Axel M Gressner

series ordinal

3

1 reference

11 August 2017

30 July 2007

1 reference

11 August 2017

Comparative Hepatology

1 reference

11 August 2017

6

1 reference

11 August 2017

7

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Creative Commons Attribution 2.0 Generic

11 August 2017

start time

30 July 2007

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

1 reference

April 2022 Public Data File from Crossref

exact match

https://scigraph.springernature.com/pub.10.1186/1476-5926-6-7

0 references

cites work

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Antifibrotic therapy in chronic liver disease

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2 October 2017

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Targeted treatments for cirrhosis

2 October 2017

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Portal tract fibrogenesis in the liver

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Epithelial-mesenchymal transition and its implications for fibrosis

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2 October 2017

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Apoptotic body engulfment by a human stellate cell line is profibrogenic.

2 October 2017

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Genetic polymorphisms and the progression of liver fibrosis: a critical appraisal

2 October 2017

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Liver fibrosis: signals leading to the amplification of the fibrogenic hepatic stellate cell

2 October 2017

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Gene regulation of connective tissue growth factor: new targets for antifibrotic therapy?

2 October 2017

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2 October 2017

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2 October 2017

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Expression of reelin in hepatic stellate cells and during hepatic tissue repair: a novel marker for the differentiation of HSC from other liver myofibroblasts

2 October 2017

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Hypoxia-induced VEGF and collagen I expressions are associated with angiogenesis and fibrogenesis in experimental cirrhosis

2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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Cytokine receptors and signaling in hepatic stellate cells

2 October 2017

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Extracellular matrix degradation and the role of hepatic stellate cells

2 October 2017

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Matrix as a modulator of hepatic fibrogenesis

2 October 2017

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Hepatic blood flow regulation by stellate cells in normal and injured liver

2 October 2017

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History, heterogeneity, developmental biology, and functions of quiescent hepatic stellate cells

2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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Rat liver myofibroblasts and hepatic stellate cells: different cell populations of the fibroblast lineage with fibrogenic potential

2 October 2017

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Expression of connective tissue growth factor in experimental rat and human liver fibrosis

2 October 2017

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Acetaldehyde enhances murine alpha2(I) collagen promoter activity by Ca2+-independent protein kinase C activation in cultured rat hepatic stellate cells

2 October 2017

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Increased expression of monocyte chemotactic protein-1 during active hepatic fibrogenesis: correlation with monocyte infiltration.

2 October 2017

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Arginine vasopressin induces contraction and stimulates growth of cultured human hepatic stellate cells.

2 October 2017

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TGF-beta-mediated hepatocellular apoptosis by rat and human hepatoma cells and primary rat hepatocytes.

2 October 2017

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Transdifferentiation of hepatic stellate cells (Ito cells) to myofibroblasts: a key event in hepatic fibrogenesis

2 October 2017

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Induction of rat liver parenchymal cell apoptosis by hepatic myofibroblasts via transforming growth factor beta

2 October 2017

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A cascade-mechanism of fat storing cell activation forms the basis of the fibrogenic reaction of the liver.

2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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Perisinusoidal stellate cells of the liver: important roles in retinol metabolism and fibrosis

2 October 2017

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Connective tissue growth factor (CTGF/CCN2) in hepatic fibrosis

2 October 2017

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Acetaldehyde increases procollagen type I and fibronectin gene transcription in cultured rat fat-storing cells through a protein synthesis-dependent mechanism.

27 July 2018

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Regulation of macrophage colony-stimulating factor in liver fat-storing cells by peptide growth factors

27 July 2018

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siRNA-mediated knockdown of connective tissue growth factor prevents N-nitrosodimethylamine-induced hepatic fibrosis in rats.

27 July 2018

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23 September 2018

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23 September 2018

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Bone marrow-derived cells express matrix metalloproteinases and contribute to regression of liver fibrosis in mice.

23 September 2018

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Regulation of transforming growth factor-beta 1-induced apoptosis and epithelial-to-mesenchymal transition by protein kinase A and signal transducers and activators of transcription 3.

23 September 2018

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Bone marrow-derived fibrocytes participate in pathogenesis of liver fibrosis.

23 September 2018

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The bone marrow functionally contributes to liver fibrosis.

23 September 2018

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23 September 2018

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Complement factor 5 is a quantitative trait gene that modifies liver fibrogenesis in mice and humans

23 September 2018

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Differentiation of in vitro-modified human peripheral blood monocytes into hepatocyte-like and pancreatic islet-like cells

23 September 2018

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NAD(P)H oxidase plays a crucial role in PDGF-induced proliferation of hepatic stellate cells

23 September 2018

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Human monocyte-derived neohepatocytes: a promising alternative to primary human hepatocytes for autologous cell therapy.

23 September 2018

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In vivo characterization of bone marrow-derived fibroblasts recruited into fibrotic lesions.

23 September 2018

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G-CSF-primed hematopoietic stem cells or G-CSF per se accelerate recovery and improve survival after liver injury, predominantly by promoting endogenous repair programs

23 September 2018

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A dual reporter gene transgenic mouse demonstrates heterogeneity in hepatic fibrogenic cell populations.

23 September 2018

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A significant proportion of myofibroblasts are of bone marrow origin in human liver fibrosis

23 September 2018

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Bone morphogenetic protein-7 signals opposing transforming growth factor beta in mesangial cells.

23 September 2018

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Commitment of bone marrow cells to hepatic stellate cells in mouse

23 September 2018

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Human hepatic stellate cells show features of antigen-presenting cells and stimulate lymphocyte proliferation

23 September 2018

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A new approach to an unbiased estimate of the hepatic stellate cell index in the rat liver: an example in healthy conditions.

23 September 2018

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BMP-7 counteracts TGF-beta1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury

23 September 2018

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The myofibroblastic conversion of peribiliary fibrogenic cells distinct from hepatic stellate cells is stimulated by platelet-derived growth factor during liver fibrogenesis.

23 September 2018

1 reference

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Adenoviral delivery of an antisense RNA complementary to the 3' coding sequence of transforming growth factor-beta1 inhibits fibrogenic activities of hepatic stellate cells

23 September 2018

1 reference

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Intracellular signaling pathways involved in acetaldehyde-induced collagen and fibronectin gene expression in human hepatic stellate cells

23 September 2018

1 reference

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The role of TGFbeta1 in initiating hepatic stellate cell activation in vivo

23 September 2018

1 reference

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Inhibition of integrin signaling with Arg-Gly-Asp motifs in rat hepatic stellate cells.

23 September 2018

1 reference

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Zonal and regional differences identified from precision mapping of vitamin A-storing lipid droplets of the hepatic stellate cells in pig liver: a novel concept of addressing the intralobular area of heterogeneity.

23 September 2018

1 reference

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Expression of tissue inhibitor of metalloproteinases 1 and 2 is increased in fibrotic human liver.

23 September 2018

1 reference

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Acetaldehyde induces c-fos and c-jun proto-oncogenes in fat-storing cell cultures through protein kinase C activation.

23 September 2018

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Early alcoholic liver injury. Activation of lipocytes in acinar zone 3 and correlation to degree of collagen formation in the Disse space

23 September 2018

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BMP-7 functions as a novel hormone to facilitate liver regeneration

23 September 2018

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Bone Morphogenic Protein-7 Induces Mesenchymal to Epithelial Transition in Adult Renal Fibroblasts and Facilitates Regeneration of Injured Kidney

14 November 2018

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Localization of liver myofibroblasts and hepatic stellate cells in normal and diseased rat livers: distinct roles of (myo-)fibroblast subpopulations in hepatic tissue repair

14 November 2018

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12 December 2020

Modulation of transforming growth factor beta response and signaling during transdifferentiation of rat hepatic stellate cells to myofibroblasts

1 reference

12 December 2020

Angiotensin II induces contraction and proliferation of human hepatic stellate cells

1 reference

12 December 2020

Connective tissue growth factor in human liver cirrhosis

1 reference

12 December 2020

Repopulation of liver endothelium by bone-marrow-derived cells

1 reference

12 December 2020

Peripheral blood fibrocytes: differentiation pathway and migration to wound sites

1 reference

12 December 2020

Contribution of bone marrow cells to liver regeneration after partial hepatectomy in mice

1 reference

12 December 2020

Identification and partial characterization of a hepatocyte-derived factor promoting proliferation of cultured fat-storing cells (parasinusoidal lipocytes)

1 reference

12 December 2020

The tightrope of therapeutic suppression of active transforming growth factor-β: high enough to fall deeply?

1 reference

12 December 2020

Setting a trap for tissue fibrosis

1 reference

12 December 2020

Bone morphogenic protein-7 and the kidney: current concepts and open questions

1 reference

12 December 2020

Inhibition of connective tissue growth factor by siRNA prevents liver fibrosis in rats

1 reference

12 December 2020

Perspectives on blockade of TGFbeta overexpression

1 reference

12 December 2020

PPAR gamma inhibits growth of rat hepatic stellate cells and TGF beta-induced connective tissue growth factor expression

1 reference

12 December 2020

Autocrine production of TGF-β confers resistance to apoptosis after an epithelial–mesenchymal transition process in hepatocytes: Role of EGF receptor ligands

1 reference

12 December 2020

Connective tissue growth factor in serum as a new candidate test for assessment of hepatic fibrosis

1 reference

12 December 2020

Does transformation of microvascular endothelial cells into myofibroblasts play a key role in the etiology and pathology of fibrotic disease?

1 reference

12 December 2020

CD133+ hepatic stellate cells are progenitor cells

1 reference

12 December 2020

Oxidative-stress and IL-6 mediate the fibrogenic effects of [corrected] Kupffer cells on stellate cells

1 reference

12 December 2020

Biliary epithelial-mesenchymal transition in posttransplantation recurrence of primary biliary cirrhosis

1 reference

12 December 2020

Regulation of hepatic stellate cell differentiation by the neurotrophin receptor p75NTR

1 reference

12 December 2020

Differential effects of TGF-β on connective tissue growth factor (CTGF/CCN2) expression in hepatic stellate cells and hepatocytes

1 reference

12 December 2020

In vitro differentiation of fat-storing cells parallels marked increase of collagen synthesis and secretion

1 reference

12 December 2020

Hepatic stellate cells: Three-dimensional structure, localization, heterogeneity and development

1 reference

12 December 2020

The role of thrombocytes in liver fibrogenesis: effects of platelet lysate and thrombocyte-derived growth factors on the mitogenic activity and glycosaminoglycan synthesis of cultured rat liver fat storing cells

1 reference

12 December 2020

Regulation of hyaluronate synthesis in rat liver fat storing cell cultures by Kupffer cells

1 reference

12 December 2020

Kupffer cell-mediated induction of synthesis and secretion of proteoglycans by rat liver fat-storing cells in culture

1 reference

12 December 2020

?Sternzellen? in the liver: Perisinusoidal cells with special reference to storage of vitamin A

1 reference

12 December 2020

Purified Rat Liver Fat-Storing Cells in Culture Divide and Contain Collagen

1 reference

12 December 2020

Ito cell heterogeneity: desmin-negative Ito cells in normal rat liver

1 reference

12 December 2020

Alteration in growth regulation of hepatocytes in primary culture obtained from cirrhotic rat: poor response to transforming growth factor-beta 1 and interferons

1 reference

12 December 2020

Molecular dissection of the mitogenic effect of hepatocytes on cultured hepatic stellate cells

1 reference

12 December 2020

High serum levels of granulocyte-macrophage colony-stimulating factor in patients with liver cirrhosis and granulocytopenia

1 reference

12 December 2020

Intralobular heterogeneity of perisinusoidal stellate cells in porcine liver

1 reference

12 December 2020

Synergism between hepatocytes and Kupffer cells in the activation of fat storing cells (perisinusoidal lipocytes)

1 reference

12 December 2020

Characterization and regulation of the latent transforming growth factor-beta complex secreted by vascular pericytes

1 reference

12 December 2020

Neutrophil-derived superoxide anion induces lipid peroxidation and stimulates collagen synthesis in human hepatic stellate cells: role of nitric oxide

1 reference

12 December 2020

Induction of neutrophil-attracting chemokines in transforming rat hepatic stellate cells

1 reference

12 December 2020

Fibrogenic effect of oxidative stress on rat hepatic stellate cells

1 reference

12 December 2020

(Latent) transforming growth factor beta in liver parenchymal cells, its injury-dependent release, and paracrine effects on rat hepatic stellate cells

1 reference

12 December 2020

Identifiers

DOI

10.1186/1476-5926-6-7

1 reference

11 August 2017

1 reference

11 August 2017

1 reference

PMCID

1994681