Selectively silencing GSK-3 isoforms reduces plaques and tangles in mouse models of Alzheimer's disease (Q36012200)

11 August 2017

Selectively silencing GSK-3 isoforms reduces plaques and tangles in mouse models of Alzheimer's disease (English)

1 reference

11 August 2017

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6

John Q Trojanowski

1 reference

11 August 2017

David E Hurtado

1

1 reference

11 August 2017

Laura Molina-Porcel

2

1 reference

11 August 2017

Jenna C Carroll

3

1 reference

11 August 2017

Caryn Macdonald

4

1 reference

11 August 2017

Awo K Aboagye

5

1 reference

11 August 2017

Virginia M-Y Lee

7

1 reference

11 August 2017

language of work or name

English

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publication date

1 May 2012

1 reference

11 August 2017

Journal of Neuroscience

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11 August 2017

32

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11 August 2017

7392-7402

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11 August 2017

21

1 reference

describes a project that uses

11 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3368584/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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Epothilone D improves microtubule density, axonal integrity, and cognition in a transgenic mouse model of tauopathy

2 October 2017

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A{beta} accelerates the spatiotemporal progression of tau pathology and augments tau amyloidosis in an Alzheimer mouse model

2 October 2017

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Abnormalities in brain structure and behavior in GSK-3alpha mutant mice

2 October 2017

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GSK-3 is a master regulator of neural progenitor homeostasis

2 October 2017

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2 October 2017

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Glycogen synthase kinase 3: more than a namesake

2 October 2017

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Tau phosphorylation: the therapeutic challenge for neurodegenerative disease

2 October 2017

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Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model

2 October 2017

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Activation of GSK-3 and phosphorylation of CRMP2 in transgenic mice expressing APP intracellular domain

2 October 2017

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Inhibition of glycogen synthase kinase-3 by lithium correlates with reduced tauopathy and degeneration in vivo

2 October 2017

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RNA interference in biology and disease

2 October 2017

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BACE overexpression alters the subcellular processing of APP and inhibits Abeta deposition in vivo

2 October 2017

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The glamour and gloom of glycogen synthase kinase-3

2 October 2017

1 reference

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Divergent roles of GSK3 and CDK5 in APP processing

2 October 2017

1 reference

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Activation of the interferon system by short-interfering RNAs

2 October 2017

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Intraventricular brain injection of adeno-associated virus type 1 (AAV1) in neonatal mice results in complementary patterns of neuronal transduction to AAV2 and total long-term correction of storage lesions in the brains of beta-glucuronidase-defici

2 October 2017

1 reference

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GSK-3alpha regulates production of Alzheimer's disease amyloid-beta peptides

2 October 2017

1 reference

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Glycogen synthase kinase 3 beta is a natural activator of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase kinase 1 (MEKK1).

2 October 2017

1 reference

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Widespread gene delivery and structure-specific patterns of expression in the brain after intraventricular injections of neonatal mice with an adeno-associated virus vector

2 October 2017

1 reference

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Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3beta conditional transgenic mice

2 October 2017

1 reference

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Presenilin 1 associates with glycogen synthase kinase-3beta and its substrate tau

2 October 2017

1 reference

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Subregion- and cell type-restricted gene knockout in mouse brain

2 October 2017

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Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

2 October 2017

1 reference

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A novel tubulin-dependent protein kinase forming a paired helical filament epitope on tau

2 October 2017

1 reference

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Molecular cloning and expression of glycogen synthase kinase-3/factor A

2 October 2017

1 reference

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Neuronal apoptosis and reversible motor deficit in dominant-negative GSK-3 conditional transgenic mice.

2 October 2017

1 reference

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Effects of mild early life stress on abnormal emotion-related behaviors in 5-HTT knockout mice

11 July 2018

1 reference

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A comparative analysis of the development of the primary somatosensory cortex: interspecies similarities during barrel and laminar development

11 July 2018

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GSK-3α/β kinases and amyloid production in vivo

11 July 2018

1 reference

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Learning, memory and search strategies of inbred mouse strains with different visual abilities in the Barnes maze.

23 September 2018

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A novel GSK-3beta inhibitor reduces Alzheimer's pathology and rescues neuronal loss in vivo.

23 September 2018

1 reference

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Glycogen synthase kinase 3alpha-specific regulation of murine hepatic glycogen metabolism

23 September 2018

1 reference

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The roles of cyclin-dependent kinase 5 and glycogen synthase kinase 3 in tau hyperphosphorylation.

23 September 2018

1 reference

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Genetic inactivation of the NMDA receptor NR2A subunit has anxiolytic- and antidepressant-like effects in mice

23 September 2018

1 reference

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Targeting amyloid-beta peptide (Abeta) oligomers by passive immunization with a conformation-selective monoclonal antibody improves learning and memory in Abeta precursor protein (APP) transgenic mice.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368584

Biology of AAV serotype vectors in liver-directed gene transfer to nonhuman primates.

23 September 2018

1 reference

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Pin1 promotes production of Alzheimer's amyloid beta from beta-cleaved amyloid precursor protein

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368584

Recombinant AAV viral vectors pseudotyped with viral capsids from serotypes 1, 2, and 5 display differential efficiency and cell tropism after delivery to different regions of the central nervous system

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368584

Lithium, a common drug for bipolar disorder treatment, regulates amyloid-beta precursor protein processing

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368584

Chronic lithium treatment decreases mutant tau protein aggregation in a transgenic mouse model.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368584

FRAT1 peptide decreases Abeta production in swAPP(751) cells

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368584

Secretion and intracellular generation of truncated Abeta in beta-site amyloid-beta precursor protein-cleaving enzyme expressing human neurons

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368584

Adeno-associated virus-mediated gene transfer to the neonatal brain

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368584

Expression of glycogen synthase kinase-3 isoforms in mouse tissues and their transcription in the brain.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368584

Lithium inhibits amyloid secretion in COS7 cells transfected with amyloid precursor protein C100.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368584

Glycogen synthase kinase-3beta regulates presenilin 1 C-terminal fragment levels

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368584

Glycogen synthase kinase-3beta phosphorylates protein tau and rescues the axonopathy in the central nervous system of human four-repeat tau transgenic mice.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368584

Selective loss of glycogen synthase kinase-3α in birds reveals distinct roles for GSK-3 isozymes in tau phosphorylation

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368584

Glycogen synthase kinase 3β is identical to tau protein kinase I generating several epitopes of paired helical filaments

14 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22623685

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1523/JNEUROSCI.0889-12.2012

1 reference

11 August 2017

1 reference

11 August 2017

1 reference