Genetic determinants of telomere length and risk of common cancers: a Mendelian randomization study (Q35999323)

11 August 2017

Genetic determinants of telomere length and risk of common cancers: a Mendelian randomization study (English)

1 reference

11 August 2017

0 references

Georgia Chenevix-Trench

11

Georgia Chenevix-Trench

0 references

Jenny Chang-Claude

34

Jenny Chang-Claude

0 references

Loic Le Marchand

44

Loic Le Marchand

0 references

Zsofia Kote-Jarai

21

Zsofia Kote-Jarai

1 reference

11 August 2017

25

Henrik Grönberg

1 reference

11 August 2017

Brandon L Pierce

51

0 references

Stephen Burgess

Stephen Burgess

3

0 references

Angela Risch

Angela Risch

13

0 references

Heike Bickeböller

Heike Bickeböller

12

0 references

Giske Ursin

Giske Ursin

38

0 references

Richard Houlston

Richard S Houlston

16

0 references

Rosalind Eeles

Rosalind A Eeles

22

0 references

Joachim Heinrich

Joachim Heinrich

20

0 references

Stephen Chanock

27

Stephen J Chanock

1 reference

11 August 2017

Fredrick Schumacher

28

0 references

John Hopper

33

John L Hopper

1 reference

11 August 2017

32

Irene L Andrulis

1 reference

11 August 2017

50

Habibul Ahsan

1 reference

11 August 2017

14

Paul Brennan

1 reference

11 August 2017

Christopher A. Haiman

29

Christopher A Haiman

1 reference

11 August 2017

30

Brian E Henderson

1 reference

11 August 2017

35

Esther M John

1 reference

11 August 2017

10

Alvaro N A Monteiro

1 reference

11 August 2017

40

David J Hunter

1 reference

11 August 2017

42

Julia A Knight

1 reference

11 August 2017

8

Christopher I Amos

1 reference

11 August 2017

45

Polly A Newcomb

1 reference

11 August 2017

39

Alice S Whittemore

1 reference

11 August 2017

26

Sonja I Berndt

1 reference

11 August 2017

36

Kathleen E Malone

1 reference

11 August 2017

2

Jennifer A Doherty

1 reference

11 August 2017

37

Marilie D Gammon

1 reference

11 August 2017

41

Stephen B Gruber

1 reference

11 August 2017

9

Thomas A Sellers

1 reference

11 August 2017

49

Michael O Woods

1 reference

11 August 2017

31

Ali Amin Al Olama

1 reference

11 August 2017

17

Maria Teresa Landi

1 reference

11 August 2017

6

Peter Kraft

1 reference

11 August 2017

5

Sara Lindström

1 reference

11 August 2017

Chenan Zhang

1

1 reference

11 August 2017

Rayjean J Hung

4

1 reference

11 August 2017

Jian Gong

7

1 reference

11 August 2017

James D Mckay

15

1 reference

11 August 2017

Maria N Timofeeva

18

1 reference

11 August 2017

Yufei Wang

19

1 reference

11 August 2017

Ken Muir

23

1 reference

11 August 2017

Fredrik Wiklund

24

1 reference

11 August 2017

Lifang Hou

43

1 reference

11 August 2017

Thomas J Hudson

46

1 reference

11 August 2017

Andrew T Chan

47

1 reference

11 August 2017

Li Li

48

1 reference

11 August 2017

GECCO and GAME-ON Network: CORECT, DRIVE, ELLIPSE, FOCI, and TRICL

52

1 reference

11 August 2017

language of work or name

English

0 references

publication date

2 July 2015

1 reference

11 August 2017

Human Molecular Genetics

1 reference

11 August 2017

24

1 reference

11 August 2017

5356-5366

1 reference

11 August 2017

18

1 reference

Using published data in Mendelian randomization: a blueprint for efficient identification of causal risk factors

11 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550826

Genetic variants associated with longer telomere length are associated with increased lung cancer risk among never-smoking women in Asia: a report from the female lung cancer consortium in Asia

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550826

The effect on melanoma risk of genes previously associated with telomere length

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550826

Determinants of telomere attrition over 1 year in healthy older women: stress and health behaviors matter

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550826

Telomere length in white blood cell DNA and lung cancer: a pooled analysis of three prospective cohorts

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550826

Longer telomere length in COPD patients with α1-antitrypsin deficiency independent of lung function

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550826

Telomere length in peripheral blood leukocytes and lung cancer risk: a large case-control study in Caucasians.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550826

Telomere length in peripheral blood leukocytes is associated with risk of colorectal cancer in Chinese population

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550826

Telomere length as a risk factor for hereditary prostate cancer

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550826

Calculating statistical power in Mendelian randomization studies.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550826

Mendelian randomization analysis with multiple genetic variants using summarized data

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550826

A genome-wide association scan (GWAS) for mean telomere length within the COGS project: identified loci show little association with hormone-related cancer risk

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550826

Longer telomere length in peripheral white blood cells is associated with risk of lung cancer and the rs2736100 (CLPTM1L-TERT) polymorphism in a prospective cohort study among women in China

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550826

Identification of seven loci affecting mean telomere length and their association with disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550826

Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550826

Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550826

Telomeres shorten at equivalent rates in somatic tissues of adults

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550826

Association of leukocyte telomere length with breast cancer risk: nested case-control findings from the Shanghai Women's Health Study

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550826

Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550826

Depressive symptoms are not associated with leukocyte telomere length: findings from the Nova Scotia Health Survey (NSHS95), a population-based study

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550826

Genome-wide meta-analysis points to CTC1 and ZNF676 as genes regulating telomere homeostasis in humans

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550826

Association of leukocyte telomere length with colorectal cancer risk: nested case-control findings from the Shanghai Women's Health Study

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550826

Influence of common genetic variation on lung cancer risk: meta-analysis of 14 900 cases and 29 485 controls

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550826

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550826

Telomere length and genetic variation in telomere maintenance genes in relation to ovarian cancer risk

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550826

Mutations in CTC1, encoding conserved telomere maintenance component 1, cause Coats plus

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550826

Molecular signature and pathway analysis of human primary squamous and adenocarcinoma lung cancers

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550826

Impartial comparative analysis of measurement of leukocyte telomere length/DNA content by Southern blots and qPCR.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550826

Meta-analysis of new genome-wide association studies of colorectal cancer risk

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550826

TERC polymorphisms are associated both with susceptibility to colorectal cancer and with longer telomeres.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550826

Shortened telomere length is associated with increased risk of cancer: a meta-analysis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550826

A prospective study of telomere length measured by monochrome multiplex quantitative PCR and risk of lung cancer

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550826

The association of telomere length and cancer: a meta-analysis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550826

Telomeric and extra-telomeric roles for telomerase and the telomere-binding proteins

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550826

Greater endogenous estrogen exposure is associated with longer telomeres in postmenopausal women at risk for cognitive decline

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550826

Power and instrument strength requirements for Mendelian randomization studies using multiple genetic variants

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550826

Telomere length and risk of incident cancer and cancer mortality

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550826

Telomere length in prospective and retrospective cancer case-control studies

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550826

Telomeres: protecting chromosomes against genome instability

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550826

Leukocyte telomere length in a population-based case-control study of ovarian cancer: a pilot study

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550826

Mean telomere length and risk of incident colorectal carcinoma: a prospective, nested case-control approach

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550826

The association between leukocyte telomere length and cigarette smoking, dietary and physical variables, and risk of prostate cancer

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550826

Genetic variation in telomere maintenance genes, telomere length, and lung cancer susceptibility

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550826

Sequence variants at the TERT-CLPTM1L locus associate with many cancer types

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550826

Telomere length, oxidative damage, antioxidants and breast cancer risk

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550826

Leukocyte telomere dynamics: longitudinal findings among young adults in the Bogalusa Heart Study

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550826

SNAP: a web-based tool for identification and annotation of proxy SNPs using HapMap

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550826

Short telomeres are a risk factor for idiopathic pulmonary fibrosis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550826

Living on a break: cellular senescence as a DNA-damage response

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550826

Telomerase, senescence and ageing

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550826

Mendelian randomization as an instrumental variable approach to causal inference

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550826

Nevus size and number are associated with telomere length and represent potential markers of a decreased senescence in vivo.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550826

Telomeres: cancer to human aging

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550826

Obesity, cigarette smoking, and telomere length in women

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550826

A DNA damage checkpoint response in telomere-initiated senescence

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550826

Molecular genetics of lung cancer

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550826

Telomere length in breast cancer patients before and after chemotherapy with or without stem cell transplantation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550826

Assessment of Lung Cancer Risk Factors by Histologic Category

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550826

Folate deficiency induces dysfunctional long and short telomeres; both states are associated with hypomethylation and DNA damage in human WIL2-NS cells.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550826

Shorter telomere length is associated with increased ovarian cancer risk in both familial and sporadic cases.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550826

Reduced telomere length variation in healthy oldest old.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550826

Telomere length and the risk of lung cancer.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550826

Telomere dysfunction: a potential cancer predisposition factor.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550826

Telomere length shortening in non-Hodgkin's lymphoma patients undergoing chemotherapy

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550826

Estrogen activates telomerase.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550826

Short telomere length, cancer survival, and cancer risk in 47102 individuals

23 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26138067

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Patterns of chromosomal imbalances in adenocarcinoma and squamous cell carcinoma of the lung

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26138067

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/HMG/DDV252

1 reference

11 August 2017

1 reference

11 August 2017

1 reference