Phospholipase D2 drives mortality in sepsis by inhibiting neutrophil extracellular trap formation and down-regulating CXCR2. (Q35992209)

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22 February 2020

title

Phospholipase D2 drives mortality in sepsis by inhibiting neutrophil extracellular trap formation and down-regulating CXCR2 (English)

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22 February 2020

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8

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22 February 2020

7

Brian A Zabel

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22 February 2020

author name string

Sung Kyun Lee

1

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22 February 2020

Sang Doo Kim

2

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22 February 2020

Minsoo Kook

3

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22 February 2020

Ha Young Lee

4

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22 February 2020

Jaewang Ghim

5

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22 February 2020

Youngwoo Choi

6

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22 February 2020

Yoe-Sik Bae

9

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language of work or name

English

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publication date

17 August 2015

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Journal of Experimental Medicine

22 February 2020

published in

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volume

212

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22 February 2020

issue

9

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22 February 2020

page(s)

1381-1390

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Endothelial deletion of phospholipase D2 reduces hypoxic response and pathological angiogenesis

22 February 2020

cites work

1 reference

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2 October 2017

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PAD4 is essential for antibacterial innate immunity mediated by neutrophil extracellular traps

2 October 2017

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Histone hypercitrullination mediates chromatin decondensation and neutrophil extracellular trap formation.

2 October 2017

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Design of isoform-selective phospholipase D inhibitors that modulate cancer cell invasiveness

2 October 2017

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Mechanisms of mortality in early and late sepsis.

2 October 2017

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Neutrophil extracellular traps kill bacteria

2 October 2017

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The immunopathogenesis of sepsis

2 October 2017

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Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care

2 October 2017

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Staphylococcus aureus infections

2 October 2017

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Phospholipase D2, a distinct phospholipase D isoform with novel regulatory properties that provokes cytoskeletal reorganization

2 October 2017

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A new generation of Ca2+ indicators with greatly improved fluorescence properties

2 October 2017

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Intravascular neutrophil extracellular traps capture bacteria from the bloodstream during sepsis

2 October 2017

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Nationwide trends of severe sepsis in the 21st century (2000-2007).

27 July 2018

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Interleukin-33 attenuates sepsis by enhancing neutrophil influx to the site of infection

23 September 2018

1 reference

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Activation of CXCR2 by extracellular matrix degradation product acetylated Pro-Gly-Pro has therapeutic effects against sepsis

23 September 2018

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12 December 2020

Expression and function of the chemokine receptors CXCR1 and CXCR2 in sepsis

1 reference

12 December 2020

Experiences with the Scandinavian recommended methods for determinations of enzymes in blood: A report by the Scandinavian Committee on Enzymes (SCE)

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12 December 2020

Septic shock and acute lung injury in rabbits with peritonitis: failure of the neutrophil response to localized infection

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12 December 2020

Identifiers

DOI

10.1084/JEM.20141813

1 reference

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22 February 2020

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22 February 2020

PubMed publication ID

26282875

1 reference