Intramembrane proteolysis of Toxoplasma apical membrane antigen 1 facilitates host-cell invasion but is dispensable for replication. (Q35982965)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22523242%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

title

Intramembrane proteolysis of Toxoplasma apical membrane antigen 1 facilitates host-cell invasion but is dispensable for replication (English)

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29 January 2020

1 reference

invasion facilitation

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3

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29 January 2020

Gary E Ward

6

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29 January 2020

author name string

Fabiola Parussini

1

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29 January 2020

Qing Tang

2

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29 January 2020

Jeffrey Mital

4

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29 January 2020

Sinisa Urban

5

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29 January 2020

language of work or name

English

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publication date

20 April 2012

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22523242%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

29 January 2020

published in

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29 January 2020

volume

109

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29 January 2020

issue

19

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29 January 2020

page(s)

7463-7468

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Juxtamembrane shedding of Plasmodium falciparum AMA1 is sequence independent and essential, and helps evade invasion-inhibitory antibodies

29 January 2020

cites work

1 reference

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Independent roles of apical membrane antigen 1 and rhoptry neck proteins during host cell invasion by apicomplexa

2 October 2017

1 reference

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Binding of Plasmodium merozoite proteins RON2 and AMA1 triggers commitment to invasion

2 October 2017

1 reference

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Host cell invasion by apicomplexan parasites: insights from the co-structure of AMA1 with a RON2 peptide

2 October 2017

1 reference

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Intramembrane cleavage of AMA1 triggers Toxoplasma to switch from an invasive to a replicative mode.

2 October 2017

1 reference

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Cell cycle-dependent, intercellular transmission of Toxoplasma gondii is accompanied by marked changes in parasite gene expression

2 October 2017

1 reference

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Toxoplasma gondii transmembrane microneme proteins and their modular design

2 October 2017

1 reference

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Rhomboid 4 (ROM4) affects the processing of surface adhesins and facilitates host cell invasion by Toxoplasma gondii

2 October 2017

1 reference

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Sequence-specific intramembrane proteolysis: identification of a recognition motif in rhomboid substrates

2 October 2017

1 reference

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An inhibitory antibody blocks interactions between components of the malarial invasion machinery

2 October 2017

1 reference

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Novel components of the Apicomplexan moving junction reveal conserved and coccidia-restricted elements

2 October 2017

1 reference

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Rhoptry neck protein RON2 forms a complex with microneme protein AMA1 in Plasmodium falciparum merozoites

2 October 2017

1 reference

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Enzymatic analysis of a rhomboid intramembrane protease implicates transmembrane helix 5 as the lateral substrate gate

2 October 2017

1 reference

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Two Plasmodium rhomboid proteases preferentially cleave different adhesins implicated in all invasive stages of malaria

2 October 2017

1 reference

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Pulling together: an integrated model of Toxoplasma cell invasion

2 October 2017

1 reference

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Plasmodium falciparum AMA1 binds a rhoptry neck protein homologous to TgRON4, a component of the moving junction in Toxoplasma gondii

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358886

Laser scanning cytometer-based assays for measuring host cell attachment and invasion by the human pathogen Toxoplasma gondii

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358886

The rhoptry neck protein RON4 re-localizes at the moving junction during Toxoplasma gondii invasion

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358886

Identification of the moving junction complex of Toxoplasma gondii: a collaboration between distinct secretory organelles

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358886

Conditional expression of Toxoplasma gondii apical membrane antigen-1 (TgAMA1) demonstrates that TgAMA1 plays a critical role in host cell invasion

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358886

A spatially localized rhomboid protease cleaves cell surface adhesins essential for invasion by Toxoplasma

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358886

A new release on life: emerging concepts in proteolysis and parasite invasion

2 October 2017

1 reference

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Proteomic analysis of cleavage events reveals a dynamic two-step mechanism for proteolysis of a key parasite adhesive complex

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358886

Substrate specificity of rhomboid intramembrane proteases is governed by helix-breaking residues in the substrate transmembrane domain

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358886

Intramembrane cleavage of microneme proteins at the surface of the apicomplexan parasite Toxoplasma gondii

2 October 2017

1 reference

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Modulation of myosin A expression by a newly established tetracycline repressor-based inducible system in Toxoplasma gondii

2 October 2017

1 reference

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The Toxoplasma homolog of Plasmodium apical membrane antigen-1 (AMA-1) is a microneme protein secreted in response to elevated intracellular calcium levels.

2 October 2017

1 reference

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Toxoplasma gondii homologue of plasmodium apical membrane antigen 1 is involved in invasion of host cells

2 October 2017

1 reference

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A merozoite receptor protein from Plasmodium knowlesi is highly conserved and distributed throughout Plasmodium

2 October 2017

1 reference

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Differential localization of full-length and processed forms of PF83/AMA-1 an apical membrane antigen of Plasmodium falciparum merozoites.

2 October 2017

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Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1114661109

Distinct mechanisms govern proteolytic shedding of a key invasion protein in apicomplexan pathogens.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1114661109

Apicomplexan rhomboids have a potential role in microneme protein cleavage during host cell invasion

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1114661109

96-Well plates providing high optical resolution for high-throughput, immunofluorescence-based screening of monoclonal antibodies against Toxoplasma gondii

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22523242

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1114661109

1 reference

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29 January 2020

0 references

1 reference

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29 January 2020

1 reference

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