Antigen-driven T cell anergy and defective memory T cell response via deregulated Rap1 activation in SPA-1-deficient mice (Q35978669)

11 August 2017

Antigen-driven T cell anergy and defective memory T cell response via deregulated Rap1 activation in SPA-1-deficient mice (English)

1 reference

11 August 2017

Daisuke Ishida

1

1 reference

11 August 2017

Hailin Yang

2

1 reference

11 August 2017

Kyoko Masuda

3

1 reference

11 August 2017

Kanami Uesugi

4

1 reference

11 August 2017

Hiroshi Kawamoto

5

1 reference

11 August 2017

Masakazu Hattori

6

1 reference

11 August 2017

Nagahiro Minato

7

1 reference

11 August 2017

language of work or name

English

0 references

publication date

4 September 2003

1 reference

Proceedings of the National Academy of Sciences of the United States of America

11 August 2017

1 reference

11 August 2017

100

1 reference

11 August 2017

19

1 reference

11 August 2017

10919-10924

1 reference

Mechanism of the spatio-temporal regulation of Ras and Rap1.

11 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=196903

Expression of a conditional AML1-ETO oncogene bypasses embryonic lethality and establishes a murine model of human t(8;21) acute myeloid leukemia

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=196903

Rap1 functions as a key regulator of T-cell and antigen-presenting cell interactions and modulates T-cell responses

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=196903

2 October 2017

T cell death and memory

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=196903

Rap1 signalling: adhering to new models

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=196903

The immunological synapse and the actin cytoskeleton: molecular hardware for T cell signaling.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=196903

The small GTPase, Rap1, mediates CD31-induced integrin adhesion

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=196903

Rap1 is a potent activation signal for leukocyte function-associated antigen 1 distinct from protein kinase C and phosphatidylinositol-3-OH kinase

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=196903

Activation of the ERK/MAPK pathway by an isoform of rap1GAP associated with G alpha(i)

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=196903

The strength of interaction at the Raf cysteine-rich domain is a critical determinant of response of Raf to Ras family small GTPases

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=196903

Rap1 GTPase-activating protein SPA-1 negatively regulates cell adhesion

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=196903

A novel adaptor protein orchestrates receptor patterning and cytoskeletal polarity in T-cell contacts

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=196903

Visualizing the dynamics of T cell activation: intracellular adhesion molecule 1 migrates rapidly to the T cell/B cell interface and acts to sustain calcium levels

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=196903

RasGRP, a Ras guanyl nucleotide- releasing protein with calcium- and diacylglycerol-binding motifs

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=196903

Human SPA-1 gene product selectively expressed in lymphoid tissues is a specific GTPase-activating protein for Rap1 and Rap2. Segregate expression profiles from a rap1GAP gene product

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=196903

Coassociation of Rap1A and Ha-Ras with Raf-1 N-terminal region interferes with ras-dependent activation of Raf-1

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=196903

The aging immune system: primer and prospectus

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=196903

RapV12 antagonizes Ras-dependent activation of ERK1 and ERK2 by LPA and EGF in Rat-1 fibroblasts

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=196903

Molecular cloning of a novel mitogen-inducible nuclear protein with a Ran GTPase-activating domain that affects cell cycle progression

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=196903

Antigen presentation by chemically modified splenocytes induces antigen-specific T cell unresponsiveness in vitro and in vivo

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=196903

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=196903

Extracellular signal-regulated activation of Rap1 fails to interfere in Ras effector signalling

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=196903

Rap1 mediates sustained MAP kinase activation induced by nerve growth factor

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=196903

The residues of Ras and Rap proteins that determine their GAP specificities.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=196903

p21ras mediates control of IL-2 gene promoter function in T cell activation.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=196903

Rap1A positively regulates T cells via integrin activation rather than inhibiting lymphocyte signaling

27 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1834525100

T cell progenitors emerge earlier than B cell progenitors in the murine fetal liver.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1834525100

Rap-specific GTPase activating protein follows an alternative mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1834525100

Costimulation: building an immunological synapse

21 January 2018

2 references

https://api.crossref.org/works/10.1073%2FPNAS.1834525100

21 January 2018

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=196903

Molecular regulation of interleukin-2 expression by CD28 co-stimulation and anergy

14 November 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1834525100

Costimulation through CD28 suppresses T cell receptor-dependent activation of the Ras-like small GTPase Rap1 in human T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1834525100

Maintenance of human T cell anergy: blocking of IL-2 gene transcription by activated Rap1

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1834525100

Myeloproliferative stem cell disorders by deregulated Rap1 activation in SPA-1-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1834525100

Efficient and rapid induction of a chronic myelogenous leukemia-like myeloproliferative disease in mice receiving P210 bcr/abl-transduced bone marrow

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12958214

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Graft-versus-leukemia effect of donor lymphocyte transfusions in marrow grafted patients

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12958214

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1834525100

1 reference

11 August 2017

0 references

1 reference

11 August 2017

PubMed publication ID

12958214

1 reference