Reelin glycoprotein: structure, biology and roles in health and disease (Q35975662)

11 August 2017

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title

Reelin glycoprotein: structure, biology and roles in health and disease (English)

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11 August 2017

Fatemi SH

1

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PubMed ID

15583703

11 August 2017

language of work or name

English

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publication date

1 March 2005

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11 August 2017

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11 August 2017

10

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11 August 2017

251-257

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11 August 2017

3

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https://scigraph.springernature.com/pub.10.1038/sj.mp.4001613

11 August 2017

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cites work

The human reelin gene: isolation, sequencing, and mapping on chromosome 7.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

The reeler gene-associated antigen on Cajal-Retzius neurons is a crucial molecule for laminar organization of cortical neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

Expression of reelin in adult mammalian blood, liver, pituitary pars intermedia, and adrenal chromaffin cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

Reduced blood levels of reelin as a vulnerability factor in pathophysiology of autistic disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

Methodological factors influencing measurement and processing of plasma reelin in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

Characterization of the various forms of the Reelin protein in the cerebrospinal fluid of normal subjects and in neurological diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

Reelin is a serine protease of the extracellular matrix

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

A panel of monoclonal antibodies against reelin, the extracellular matrix protein defective in reeler mutant mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

Reelin molecules assemble together to form a large protein complex, which is inhibited by the function-blocking CR-50 antibody

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

Reelin is a ligand for lipoprotein receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

Direct binding of Reelin to VLDL receptor and ApoE receptor 2 induces tyrosine phosphorylation of disabled-1 and modulates tau phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

Reelin binds alpha3beta1 integrin and inhibits neuronal migration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

Receptor clustering is involved in Reelin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

Lipoprotein receptors: signaling functions in the brain?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

Reelin is preferentially expressed in neurons synthesizing gamma-aminobutyric acid in cortex and hippocampus of adult rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

Defective corticogenesis and reduction in Reelin immunoreactivity in cortex and hippocampus of prenatally infected neonatal mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

Reelin, the extracellular matrix protein deficient in reeler mutant mice, is processed by a metalloproteinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

The central fragment of Reelin, generated by proteolytic processing in vivo, is critical to its function during cortical plate development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

Identification of reelin-induced sites of tyrosyl phosphorylation on disabled 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

Reelin-mediated signaling locally regulates protein kinase B/Akt and glycogen synthase kinase 3beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

Fyn tyrosine kinase is a critical regulator of disabled-1 during brain development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

The Jnk1 and Jnk2 protein kinases are required for regional specific apoptosis during early brain development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

Regulation of protein tyrosine kinase signaling by substrate degradation during brain development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

Regulation of actin cytoskeleton by mDab1 through N-WASP and ubiquitination of mDab1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

Induction of filopodium formation by a WASP-related actin-depolymerizing protein N-WASP

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

Actin polymerization is induced by Arp2/3 protein complex at the surface of Listeria monocytogenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

The Cbl family and other ubiquitin ligases: destructive forces in control of antigen receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

An early development defect in the cerebral cortex of the reeler mouse. A morphological study leading to a hypothesis concerning the action of the mutant gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

Rescue of ataxia and preplate splitting by ectopic expression of Reelin in reeler mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

Gender effect on Purkinje cell loss in the cerebellum of the heterozygous reeler mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

Reeler/Disabled-like disruption of neuronal migration in knockout mice lacking the VLDL receptor and ApoE receptor 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

Reelin mutations in mouse and man: from reeler mouse to schizophrenia, mood disorders, autism and lissencephaly

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

The phenotypic characteristics of heterozygous reeler mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

Early serotonergic projections to Cajal-Retzius cells: relevance for cortical development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

Enhanced dizocilpine efficacy in heterozygous reeler mice relates to GABA turnover downregulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

Sensitization and habituation of the acoustic startle reflex in patients with schizophrenia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

Brain anatomy and sensorimotor gating in Asperger's syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

Reelin and brain development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

Reelin immunoreactivity in the larval sea lamprey brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

Expression of reelin, the gene responsible for the reeler mutation, in embryonic development and adulthood in the mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

A decrease of reelin expression as a putative vulnerability factor in schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

Reduction in Reelin immunoreactivity in hippocampus of subjects with schizophrenia, bipolar disorder and major depression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

Reelin-expressing neurons in the postnatal and adult human hippocampal formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

Reelin and disabled-1 expression in developing and mature human cortical neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

Reelin, Disabled 1, and beta 1 integrins are required for the formation of the radial glial scaffold in the hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

Localization of ApoER2, VLDLR and Dab1 in radial glia: groundwork for a new model of reelin action during cortical development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

Reelin and ApoE receptors cooperate to enhance hippocampal synaptic plasticity and learning

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

Disrupted synaptic development in the hypoxic newborn brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

Decrease in reelin and glutamic acid decarboxylase67 (GAD67) expression in schizophrenia and bipolar disorder: a postmortem brain study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

The axonal chemorepellant semaphorin 3A is increased in the cerebellum in schizophrenia and may contribute to its synaptic pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

Interstitial white matter neurons express less reelin and are abnormally distributed in schizophrenia: towards an integration of molecular and morphologic aspects of the neurodevelopmental hypothesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

Molecular abnormalities of the hippocampus in severe psychiatric illness: postmortem findings from the Stanley Neuropathology Consortium

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

Epigenetic downregulation of GABAergic function in schizophrenia: potential for pharmacological intervention?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

Methylomics in psychiatry: Modulation of gene-environment interactions may be through DNA methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

GABAergic cortical neuron chromatin as a putative target to treat schizophrenia vulnerability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

DNA-methyltransferase 1 mRNA is selectively overexpressed in telencephalic GABAergic interneurons of schizophrenia brains

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

Association analysis of polymorphic CGG repeat in 5' UTR of the reelin and VLDLR genes with schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

Identification of a single nucleotide polymorphism at the 5' promoter region of human reelin gene and association study with schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

Reelin gene alleles and haplotypes as a factor predisposing to autistic disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

Reelin gene alleles and susceptibility to autism spectrum disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

Absence of association between a polymorphic GGC repeat in the 5' untranslated region of the reelin gene and autism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

Analysis of reelin as a candidate gene for autism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

Alleles of a reelin CGG repeat do not convey liability to autism in a sample from the CPEA network

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

Lack of evidence for an association between WNT2 and RELN polymorphisms and autism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

Autosomal recessive lissencephaly with cerebellar hypoplasia is associated with human RELN mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

Interaction of reelin signaling and Lis1 in brain development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

Altered levels of cerebrospinal fluid reelin in frontotemporal dementia and Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

Alzheimer's disease: neurodevelopment converges with neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

Very low density lipoprotein receptor in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

Juxtaposition of CNR protocadherins and reelin expression in the developing spinal cord

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

Components of the reelin signaling pathway are expressed in the spinal cord

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

Location of preganglionic neurons is independent of birthdate but is correlated to reelin-producing cells in the spinal cord

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

Evidence for a cell-specific action of Reelin in the spinal cord

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

Transient and compartmental expression of the reeler gene product reelin in the developing rat striatum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

Expression of reelin in hepatic stellate cells and during hepatic tissue repair: a novel marker for the differentiation of HSC from other liver myofibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

CASK and its target gene Reelin were co-upregulated in human esophageal carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

A substractive PCR-based cDNA library from human odontoblast cells: identification of novel genes expressed in tooth forming cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

Dynamic expression patterns of the new protocadherin families CNRs and Pcdh-gamma during mouse odontogenesis: comparison with reelin expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

Gene expression profiling reveals a highly specialized genetic program of plasma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

Reelin is a secreted glycoprotein recognized by the CR-50 monoclonal antibody.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

7 January 2021

Events governing organization of postmigratory neurons: studies on brain development in normal and reeler mice.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

7 January 2021

Maternal influenza infection causes marked behavioral and pharmacological changes in the offspring.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

7 January 2021

Effects of testosterone on Reelin expression in the brain of male European starlings

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

7 January 2021

The paleocortical ventricle is the origin of reelin-expressing neurons in the marginal zone of the foetal human neocortex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001613

7 January 2021

Identifiers

DOI

10.1038/SJ.MP.4001613

1 reference

11 August 2017

1 reference

PubMed ID

15583703