Test systems to study the structure and function of uncoupling protein 1: a critical overview. (Q35972265)

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3 February 2020

title

Test systems to study the structure and function of uncoupling protein 1: a critical overview (English)

1 reference

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3 February 2020

1

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3 February 2020

Tobias Fromme

2

1 reference

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3 February 2020

Martin Klingenspor

3

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3 February 2020

author name string

Verena Hirschberg

1

1 reference

11 August 2017

Tobias Fromme

2

1 reference

11 August 2017

Martin Klingenspor

3

1 reference

11 August 2017

8 November 2011

1 reference

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Frontiers in Endocrinology

3 February 2020

published in

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3 February 2020

volume

2

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3 February 2020

page(s)

63

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Adipose tissue development--impact of the early life environment

3 February 2020

cites work

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2 October 2017

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2 October 2017

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2 October 2017

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Synergy of fatty acid and reactive alkenal activation of proton conductance through uncoupling protein 1 in mitochondria

2 October 2017

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Ectopic UCP1 gene expression in HepG2 cells affects ATP production

2 October 2017

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Physiological functions of the mitochondrial uncoupling proteins UCP2 and UCP3.

2 October 2017

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PPARgamma in the control of brown adipocyte differentiation.

2 October 2017

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Genetic and physiological analysis of the role of uncoupling proteins in human energy homeostasis

2 October 2017

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Both retinoic-acid-receptor- and retinoid-X-receptor-dependent signalling pathways mediate the induction of the brown-adipose-tissue-uncoupling-protein-1 gene by retinoids

2 October 2017

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Uncoupling protein-3: a new member of the mitochondrial carrier family with tissue-specific expression

2 October 2017

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Mice lacking mitochondrial uncoupling protein are cold-sensitive but not obese

2 October 2017

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Human immortalized brown adipocytes express functional beta3-adrenoceptor coupled to lipolysis

2 October 2017

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Cloning and characterization of an uncoupling protein homolog: a potential molecular mediator of human thermogenesis

2 October 2017

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Uncoupling protein-2: a novel gene linked to obesity and hyperinsulinemia

2 October 2017

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Role of uncoupled and non-coupled oxidations in maintenance of safely low levels of oxygen and its one-electron reductants

2 October 2017

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On the mechanism of fatty acid-induced proton transport by mitochondrial uncoupling protein

2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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The uncoupling protein from brown fat mitochondria is related to the mitochondrial ADP/ATP carrier. Analysis of sequence homologies and of folding of the protein in the membrane.

2 October 2017

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The reconstituted isolated uncoupling protein is a membrane potential driven H+ translocator

2 October 2017

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Stable expression of functional mitochondrial uncoupling protein in Chinese hamster ovary cells.

2 October 2017

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Functional reconstitution of rat uncoupling protein following its high level expression in yeast

2 October 2017

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Fatty acid circuit as a physiological mechanism of uncoupling of oxidative phosphorylation

2 October 2017

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Hibernoma formation in transgenic mice and isolation of a brown adipocyte cell line expressing the uncoupling protein gene

2 October 2017

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A role for brown adipose tissue in diet-induced thermogenesis

2 October 2017

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Induction of uncoupling protein-1 in mouse embryonic fibroblast-derived adipocytes by retinoic acid

2 October 2017

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Uncoupling protein-1 (UCP1) contributes to the basal proton conductance of brown adipose tissue mitochondria.

11 July 2018

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Assessment of a high-throughput screening methodology for the measurement of purified UCP1 uncoupling activity

11 July 2018

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Uncoupling protein 1 affects the yeast mitoproteome and oxygen free radical production

11 July 2018

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Ubiquinone is not required for proton conductance by uncoupling protein 1 in yeast mitochondria

11 July 2018

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Reconstitution of recombinant uncoupling proteins: UCP1, -2, and -3 have similar affinities for ATP and are unaffected by coenzyme Q10.

11 July 2018

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The mechanism of proton transport mediated by mitochondrial uncoupling proteins

11 July 2018

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Photoactivated azido fatty acid irreversibly inhibits anion and proton transport through the mitochondrial uncoupling protein

11 July 2018

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Effect of fatty acids on H+ transport activity of the reconstituted uncoupling protein.

11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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Phylogenetic differences of mammalian basal metabolic rate are not explained by mitochondrial basal proton leak.

24 September 2018

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Gene expression in human brown adipose tissue.

24 September 2018

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Uncoupling protein 1 decreases superoxide production in brown adipose tissue mitochondria

24 September 2018

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Uncoupling protein-1 is not leaky

24 September 2018

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UCP1 ectopically expressed in murine muscle displays native function and mitigates mitochondrial superoxide production

24 September 2018

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Functional characterisation of UCP1 in the common carp: uncoupling activity in liver mitochondria and cold-induced expression in the brain

24 September 2018

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A new automated technique for the reconstitution of hydrophobic proteins into planar bilayer membranes. Studies of human recombinant uncoupling protein 1.

24 September 2018

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UCP1 and defense against oxidative stress. 4-Hydroxy-2-nonenal effects on brown fat mitochondria are uncoupling protein 1-independent.

24 September 2018

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On the mechanism of mitochondrial uncoupling protein 1 function

24 September 2018

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Native UCP1 displays simple competitive kinetics between the regulators purine nucleotides and fatty acids.

24 September 2018

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Transport kinetics of uncoupling proteins. Analysis of UCP1 reconstituted in planar lipid bilayers

24 September 2018

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Brown adipose tissue: a factor to consider in symmetrical tracer uptake in the neck and upper chest region

24 September 2018

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A mitochondrial uncoupling artifact can be caused by expression of uncoupling protein 1 in yeast

24 September 2018

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Mitochondrial proton leak in brown adipose tissue mitochondria of Ucp1-deficient mice is GDP insensitive.

24 September 2018

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Functional assessment of white and brown adipocyte development and energy metabolism in cell culture. Dissociation of terminal differentiation and thermogenesis in brown adipocytes.

24 September 2018

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12 December 2020

Thermoregulation and non-shivering thermogenesis in the genetically obese (ob/ob) mouse

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12 December 2020

Brown adipose tissue uncoupling protein content in human infants, children and adults

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12 December 2020

Identification of the pH sensor for nucleotide binding in the uncoupling protein from brown adipose tissue

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12 December 2020

Transport of anions and protons by the mitochondrial uncoupling protein and its regulation by nucleotides and fatty acids. A new look at old hypotheses

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12 December 2020

Brown-adipose-tissue mitochondria: the regulation of the 32000-Mr uncoupling protein by fatty acids and purine nucleotides

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12 December 2020

Body mass dependence of H+ leak in mitochondria and its relevance to metabolic rate

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12 December 2020

The uncoupling protein from brown adipose tissue mitochondria is a dimer. A hydrodynamic study

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12 December 2020

The uncoupling protein dimer can form a disulfide cross-link between the mobile C-terminal SH groups

1 reference

12 December 2020

Polyunsaturated fatty acids activate human uncoupling proteins 1 and 2 in planar lipid bilayers

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12 December 2020

Brown adipose tissue in patients with phaeochromocytoma

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12 December 2020

Organ blood flow and brown adipose tissue oxygen consumption during noradrenaline-induced nonshivering thermogenesis in the Djungarian hamster

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12 December 2020

Inhibited respiration and ATPase activity of rat liver mitochondria under conditions of matrix condensation

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12 December 2020

Structure and function of the uncoupling protein from brown adipose tissue

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12 December 2020

beta(3)-adrenergic stimulation differentially inhibits insulin signaling and decreases insulin-induced glucose uptake in brown adipocytes

1 reference

12 December 2020

Characteristics of the isolated purine nucleotide binding protein from brown fat mitochondria

1 reference

12 December 2020

Cellular and molecular large-scale features of fetal adipose tissue: is bovine perirenal adipose tissue brown?

1 reference

12 December 2020

Identification by site-directed mutagenesis of three arginines in uncoupling protein that are essential for nucleotide binding and inhibition

1 reference

12 December 2020

The possible proton translocating activity of the mitochondrial uncoupling protein of brown adipose tissue. Reconstitution studies in liposomes

1 reference

12 December 2020

In the uncoupling protein from brown adipose tissue the C-terminus protrudes to the c-side of the membrane as shown by tryptic cleavage

1 reference

12 December 2020

Chimeric proteins between UCP1 and UCP3: the middle third of UCP1 is necessary and sufficient for activation by fatty acids

1 reference

12 December 2020

Isolation of the uncoupling protein from brown adipose tissue mitochondria

1 reference

12 December 2020

In the uncoupling protein (UCP-1) His-214 is involved in the regulation of purine nucleoside triphosphate but not diphosphate binding

1 reference

12 December 2020

Fluorescent nucleotide derivatives as specific probes for the uncoupling protein: thermodynamics and kinetics of binding and the control by pH

1 reference

12 December 2020

Nonshivering thermogenesis in the rat. II. Measurements of blood flow with microspheres point to brown adipose tissue as the dominant site of the calorigenesis induced by noradrenaline

1 reference

12 December 2020

Identifiers

DOI

10.3389/FENDO.2011.00063

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22654819%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22654819%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

PubMed publication ID

22654819

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22654819%20AND%20SRC:MED&resulttype=core&format=json