Molecular physiology, pathology, and regulation of the growth hormone/insulin-like growth factor-I system (Q35953404)

11 August 2017

1 reference

title

Molecular physiology, pathology, and regulation of the growth hormone/insulin-like growth factor-I system (English)

1 reference

11 August 2017

Joachim Woelfle

1

1 reference

11 August 2017

Dennis J Chia

2

1 reference

11 August 2017

Mylynda B Massart-Schlesinger

3

1 reference

11 August 2017

Paula Moyano

4

1 reference

11 August 2017

Peter Rotwein

5

1 reference

11 August 2017

10 November 2004

1 reference

11 August 2017

1 reference

11 August 2017

20

1 reference

11 August 2017

295-302

1 reference

11 August 2017

3

1 reference

https://scigraph.springernature.com/pub.10.1007/s00467-004-1602-1

11 August 2017

0 references

cites work

Mammary cancer in transgenic mice expressing insulin-like growth factor II (IGF-II)

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00467-004-1602-1

Identification of SH2-Bbeta as a substrate of the tyrosine kinase JAK2 involved in growth hormone signaling

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00467-004-1602-1

Growth hormone stimulates the tyrosine phosphorylation of the insulin receptor substrate-1 and its association with phosphatidylinositol 3-kinase in primary adipocytes

21 January 2018

1 reference

12 December 2020

Characterization of deoxyribonucleic acid-protein interactions at a growth hormone-inducible nuclease hypersensitive site in the rat insulin-like growth factor-I gene

1 reference

12 December 2020

Activation of acute phase response factor (APRF)/Stat3 transcription factor by growth hormone.

1 reference

12 December 2020

Evidence that anabolic effects of PTH on bone require IGF-I in growing mice

1 reference

12 December 2020

Interaction of Growth Hormone-activated STATs with SH2-containing Phosphotyrosine Phosphatase SHP-1 and Nuclear JAK2 Tyrosine Kinase

1 reference

12 December 2020

Regulation of signal transducer and activator of transcription (STAT) 5b activation by the temporal pattern of growth hormone stimulation

1 reference

12 December 2020

Cell nonautonomy of C. elegans daf-2 function in the regulation of diapause and life span

1 reference

12 December 2020

Insulin-like growth factor I is essential for terminal end bud formation and ductal morphogenesis during mammary development

1 reference

12 December 2020

Roles of growth hormone and insulin-like growth factor 1 in mouse postnatal growth.

1 reference

12 December 2020

Two putative GATA motifs in the proximal exon 1 promoter of the rat insulin-like growth factor I gene regulate basal promoter activity

1 reference

12 December 2020

Myogenic vector expression of insulin-like growth factor I stimulates muscle cell differentiation and myofiber hypertrophy in transgenic mice

1 reference

12 December 2020

daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans

1 reference

12 December 2020

Growth Hormone Induction of Hepatic Serine Protease Inhibitor 2.1 Transcription Is Mediated by a Stat5-related Factor Binding Synergistically to Two γ-Activated Sites

1 reference

12 December 2020

A little lesson in growth regulation

1 reference

12 December 2020

A CACCC box in the proximal exon 2 promoter of the rat insulin-like growth factor I gene is required for basal promoter activity

1 reference

12 December 2020

Differential gene expression in the rat soleus muscle during early work overload-induced hypertrophy

1 reference

12 December 2020

Growth hormone preferentially induces the rapid, transient expression of SOCS-3, a novel inhibitor of cytokine receptor signaling

1 reference

12 December 2020

The role of the growth hormone (GH) receptor and JAK1 and JAK2 kinases in the activation of Stats 1, 3, and 5 by GH.

1 reference

12 December 2020

Growth hormone-promoted tyrosyl phosphorylation of SHC proteins and SHC association with Grb2

1 reference

12 December 2020

CPAP is a novel stat5-interacting cofactor that augments stat5-mediated transcriptional activity

1 reference

12 December 2020

Insulin-like growth factors I and II. Peptide, messenger ribonucleic acid and gene structures, serum, and tissue concentrations

1 reference

12 December 2020

Growth hormone (GH) insensitivity due to primary GH receptor deficiency

1 reference

12 December 2020

Reduced growth of human breast cancer xenografts in hosts homozygous for the lit mutation

1 reference

12 December 2020

Bone homeostasis in growth hormone receptor-null mice is restored by IGF-I but independent of Stat5.

1 reference

12 December 2020

Insulin receptor substrate-1 in osteoblast is indispensable for maintaining bone turnover

1 reference

12 December 2020

Mechanisms of growth hormone (GH) action. Identification of conserved Stat5 binding sites that mediate GH-induced insulin-like growth factor-I gene activation

1 reference

12 December 2020

Blockade of the type I somatomedin receptor inhibits growth of human breast cancer cells in athymic mice

1 reference

12 December 2020

Rapid changes in nuclear protein tyrosine phosphorylation after growth hormone treatment in vivo. Identification of phosphorylated mitogen-activated protein kinase and STAT91.

1 reference

12 December 2020

Binding of a growth hormone-inducible nuclear factor is mediated by tyrosine phosphorylation

1 reference

12 December 2020

Stat5a and Stat5b proteins have essential and nonessential, or redundant, roles in cytokine responses

1 reference

12 December 2020

Plasma insulin-like growth factor-I, insulin-like growth factor-binding proteins, and prostate cancer risk: a prospective study

1 reference

12 December 2020

Signaling by insulin-like growth factors in paralyzed skeletal muscle: rapid induction of IGF1 expression in muscle fibers and prevention of interstitial cell proliferation by IGF-BP5 and IGF-BP4.

1 reference

12 December 2020

A conserved regulatory system for aging

1 reference

12 December 2020

Essential promoter elements are located within the 5' untranslated region of human insulin-like growth factor-I exon I.

1 reference

12 December 2020

Growth hormone stimulation of the mitogen-activated protein kinase pathway is cell type specific

1 reference

12 December 2020

Viral mediated expression of insulin-like growth factor I blocks the aging-related loss of skeletal muscle function

1 reference

12 December 2020

Requirement of STAT5b for sexual dimorphism of body growth rates and liver gene expression

1 reference

12 December 2020

The GH-IGF-I axis and breast cancer.

1 reference

12 December 2020

Growth hormone stimulates tyrosine phosphorylation of JAK2 and STAT5, but not insulin receptor substrate-1 or SHC proteins in liver and skeletal muscle of normal rats in vivo

1 reference

12 December 2020

Plasma insulin-like growth factor-I and prostate cancer risk: a prospective study

1 reference

12 December 2020

Growth hormone activation of Stat 1, Stat 3, and Stat 5 in rat liver. Differential kinetics of hormone desensitization and growth hormone stimulation of both tyrosine phosphorylation and serine/threonine phosphorylation

1 reference

12 December 2020

Prospective study of colorectal cancer risk in men and plasma levels of insulin-like growth factor (IGF)-I and IGF-binding protein-3.

1 reference

12 December 2020

Signaling molecules involved in coupling growth hormone receptor to mitogen-activated protein kinase activation

1 reference

12 December 2020

Acute control of insulin-like growth factor-I gene transcription by growth hormone through Stat5b.

1 reference

12 December 2020

Involvement of the Src homology 2-containing tyrosine phosphatase SHP-2 in growth hormone signaling

1 reference

12 December 2020

Growth hormone, interferon-gamma, and leukemia inhibitory factor utilize insulin receptor substrate-2 in intracellular signaling

1 reference

12 December 2020

The IL-7 receptor controls the accessibility of the TCRgamma locus by Stat5 and histone acetylation

1 reference

12 December 2020

Prospective study of IGF-I, IGF-binding proteins, and breast cancer risk, in northern and southern Sweden.

1 reference

12 December 2020

daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans

1 reference

12 December 2020

Structure of the chicken insulin-like growth factor I gene reveals conserved promoter elements.

1 reference

12 December 2020

Growth enhancement in suppressor of cytokine signaling 2 (SOCS-2)-deficient mice is dependent on signal transducer and activator of transcription 5b (STAT5b)

1 reference

12 December 2020

An inducible nuclear factor binds to a growth hormone-regulated gene

1 reference

12 December 2020

The somatomedin hypothesis: 2001.

1 reference

12 December 2020

High frequency of mammary adenocarcinomas in metallothionein promoter-human growth hormone transgenic mice created from two different strains of mice

1 reference

12 December 2020

Stats: transcriptional control and biological impact

1 reference

12 December 2020

Circulating concentrations of insulin-like growth factor I and risk of breast cancer

1 reference

12 December 2020

Structure and function of a human insulin-like growth factor-I gene promoter

1 reference

12 December 2020

Growth hormone-induced tyrosyl phosphorylation and deoxyribonucleic acid binding activity of Stat5A and Stat5B.

1 reference

12 December 2020

The major promoter of the rat insulin-like growth factor-I gene binds a protein complex that is required for basal expression

1 reference

12 December 2020

Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein

1 reference

12 December 2020

Activation of insulin-like growth factor gene expression during work-induced skeletal muscle growth

1 reference

12 December 2020

Parathyroid hormone exerts disparate effects on osteoblast differentiation depending on exposure time in rat osteoblastic cells

1 reference

12 December 2020

Regulation of Start Site Usage in the Leader Exons of the Rat Insulin-Like Growth Factor-I Gene by Development, Fasting, and Diabetes

1 reference

12 December 2020

Muscle-specific inactivation of the IGF-I receptor induces compensatory hyperplasia in skeletal muscle

1 reference

12 December 2020

A mutant Drosophila insulin receptor homolog that extends life-span and impairs neuroendocrine function

1 reference

12 December 2020

Localized Igf-1 transgene expression sustains hypertrophy and regeneration in senescent skeletal muscle

1 reference

12 December 2020

Signaling pathways activated by the growth hormone receptor

1 reference

12 December 2020

Insulin-like growth factors and their binding proteins: biological actions

1 reference

12 December 2020

Mosaic evolution of the insulin-like growth factors. Organization, sequence, and expression of the rat insulin-like growth factor I gene.

1 reference

12 December 2020

The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans

1 reference

12 December 2020

Growth hormone, interferon-gamma, and leukemia inhibitory factor promoted tyrosyl phosphorylation of insulin receptor substrate-1

1 reference

12 December 2020

Lifespan extension and delayed immune and collagen aging in mutant mice with defects in growth hormone production

1 reference

12 December 2020

A hormonally controlled serum factor which stimulates sulfate incorporation by cartilage in vitro.

1 reference

12 December 2020

Assessment of growth parameters and life span of GHR/BP gene-disrupted mice.

1 reference

12 December 2020

Deacetylase activity is required for recruitment of the basal transcription machinery and transactivation by STAT5.

1 reference

12 December 2020

IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice

1 reference

12 December 2020

Growth hormone stimulates the tyrosine phosphorylation and association of p125 focal adhesion kinase (FAK) with JAK2. Fak is not required for stat-mediated transcription

1 reference

12 December 2020

1 reference

12 December 2020

The endocrine regulation of aging by insulin-like signals

1 reference

12 December 2020

In vivo growth hormone treatment rapidly stimulates the tyrosine phosphorylation and activation of Stat3.

1 reference

12 December 2020

Dwarf mice and the ageing process.

1 reference

12 December 2020

Effect of parathyroid hormone (1-34) on fractures and bone mineral density in postmenopausal women with osteoporosis

1 reference

12 December 2020

Growth hormone regulation of SIRP and SHP-2 tyrosyl phosphorylation and association

1 reference

12 December 2020

Growth hormone rapidly activates insulin-like growth factor I gene transcription in vivo

1 reference

12 December 2020

IGF-I receptor mutations resulting in intrauterine and postnatal growth retardation

1 reference

12 December 2020

Mutations of the growth hormone receptor in children with idiopathic short stature. The Growth Hormone Insensitivity Study Group

1 reference

12 December 2020

Functional analysis of the rat insulin-like growth factor I gene and identification of an IGF-I gene promoter

1 reference

12 December 2020

Tyrosine phosphorylation of the EGF receptor by the kinase Jak2 is induced by growth hormone

1 reference

12 December 2020

Targeted expression of des(1-3) human insulin-like growth factor I in transgenic mice influences mammary gland development and IGF-binding protein expression

1 reference

12 December 2020

Parathyroid hormone enhances the transcript and polypeptide levels of insulin-like growth factor I in osteoblast-enriched cultures from fetal rat bone

1 reference

12 December 2020

STAT5-induced Id-1 transcription involves recruitment of HDAC1 and deacetylation of C/EBPbeta

1 reference

12 December 2020

Muscle-specific expression of insulin-like growth factor I counters muscle decline in mdx mice

1 reference

12 December 2020

Induction of insulin-like growth factor I messenger ribonucleic acid during regeneration of rat skeletal muscle

1 reference

12 December 2020

Intrauterine growth retardation and postnatal growth failure associated with deletion of the insulin-like growth factor I gene

1 reference

12 December 2020

Growth hormone insensitivity associated with a STAT5b mutation

1 reference

12 December 2020

IGF-I is required for normal embryonic growth in mice

1 reference

12 December 2020

Plasma insulin-like growth factor 1, insulin-like growth factor binding protein 3, and risk of colorectal cancer: a prospective study in northern Sweden

1 reference

12 December 2020

Tissue and development specific regulation of a complex family of rat insulin-like growth factor I messenger ribonucleic acids.

1 reference

12 December 2020

Structure of the chum salmon insulin-like growth factor I gene

1 reference

12 December 2020

Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo

1 reference

12 December 2020

p300/CREB-binding protein enhances the prolactin-mediated transcriptional induction through direct interaction with the transactivation domain of Stat5, but does not participate in the Stat5-mediated suppression of the glucocorticoid response

1 reference

12 December 2020

Regulation of insulin-like growth factor I (IGF-I) gene expression in brain of transgenic mice expressing an IGF-I-luciferase fusion gene.

1 reference

12 December 2020

Insulin-like growth factor-I and cancer risk.

1 reference

12 December 2020

A sequence repeat in the insulin-like growth factor-1 gene and risk of breast cancer.

1 reference

12 December 2020

10.1007/S00467-004-1602-1

Identifiers

DOI

1 reference

11 August 2017

1 reference