Distinct gene expression profiling after infection of immature human monocyte-derived dendritic cells by the attenuated poxvirus vectors MVA and NYVAC. (Q35947683)

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English	Distinct gene expression profiling after infection of immature human monocyte-derived dendritic cells by the attenuated poxvirus vectors MVA and NYVAC.	scientific article

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31 December 2019

Distinct gene expression profiling after infection of immature human monocyte-derived dendritic cells by the attenuated poxvirus vectors MVA and NYVAC (English)

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31 December 2019

vector-borne disease

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Jose M Gonzalez

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31 December 2019

Luis A Lopez-Fernandez

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Mariano Esteban

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Mariano Esteban

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Susana Guerra

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José Luis Nájera

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José M Gatell

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Teresa Gallart

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30 May 2007

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31 December 2019

Journal of Virology

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8707-8721

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31 December 2019

Vaccinia virus infection of mature dendritic cells results in activation of virus-specific naïve CD8+ T cells: a potential mechanism for direct presentation

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Suppression of proinflammatory signal transduction and gene expression by the dual nucleic acid binding domains of the vaccinia virus E3L proteins

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Differences and similarities in viral life cycle progression and host cell physiology after infection of human dendritic cells with modified vaccinia virus Ankara and vaccinia virus.

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Cellular and biochemical differences between two attenuated poxvirus vaccine candidates (MVA and NYVAC) and role of the C7L gene

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Host response to the attenuated poxvirus vector NYVAC: upregulation of apoptotic genes and NF-kappaB-responsive genes in infected HeLa cells.

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Evasion of innate immunity by vaccinia virus

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Synergistic DNA-MVA prime-boost vaccination regimes for malaria and tuberculosis

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Role of viral factor E3L in modified vaccinia virus ankara infection of human HeLa Cells: regulation of the virus life cycle and identification of differentially expressed host genes

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The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses

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Therapeutic vaccination with MVA E2 can eliminate precancerous lesions (CIN 1, CIN 2, and CIN 3) associated with infection by oncogenic human papillomavirus

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Microarray analysis reveals characteristic changes of host cell gene expression in response to attenuated modified vaccinia virus Ankara infection of human HeLa cells.

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2 October 2017

The uses of poxviruses as vectors

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Shared modes of protection against poxvirus infection by attenuated and conventional smallpox vaccine viruses

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Replication of modified vaccinia virus Ankara in primary chicken embryo fibroblasts requires expression of the interferon resistance gene E3L.

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Cellular gene expression survey of vaccinia virus infection of human HeLa cells.

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Implications for RNase L in prostate cancer biology

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The poxvirus protein A52R targets Toll-like receptor signaling complexes to suppress host defense

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Viral mimicry of cytokines, chemokines and their receptors

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Poly(ADP-ribose) polymerase-1 cleavage during apoptosis: an update

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2 October 2017

The interferon antiviral response: from viral invasion to evasion

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2 October 2017

Blockade of interferon induction and action by the E3L double-stranded RNA binding proteins of vaccinia virus.

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2 October 2017

Dendritic cells: specialized and regulated antigen processing machines

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2 October 2017

Geranylgeranylacetone induces antiviral gene expression in human hepatoma cells

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2 October 2017

IRF3 and IRF7 phosphorylation in virus-infected cells does not require double-stranded RNA-dependent protein kinase R or Ikappa B kinase but is blocked by Vaccinia virus E3L protein

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Identification of distinct signaling pathways leading to the phosphorylation of interferon regulatory factor 3

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Poxvirus as a vector to transduce human dendritic cells for immunotherapy: abortive infection but reduced APC function

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Viral interference with IL-1 and toll signaling

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Vaccinia virus-related events and phenotypic changes after infection of dendritic cells derived from human monocytes

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2 October 2017

The vaccinia virus 39-kDa protein forms a stable complex with the p4a/4a major core protein early in morphogenesis

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2 October 2017

The antiviral enzymes PKR and RNase L suppress gene expression from viral and non-viral based vectors

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Cell activation and apoptosis by bacterial lipoproteins through toll-like receptor-2

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Maturation, activation, and protection of dendritic cells induced by double-stranded RNA

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2 October 2017

Inhibition of double-stranded RNA-dependent protein kinase PKR by vaccinia virus E3: role of complex formation and the E3 N-terminal domain

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Dendritic cells and the control of immunity

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Host-range restriction of vaccinia virus E3L-specific deletion mutants

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TLR3 and TLR7 are targeted to the same intracellular compartments by distinct regulatory elements

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Enhanced immunogenicity for CD8+ T cell induction and complete protective efficacy of malaria DNA vaccination by boosting with modified vaccinia virus Ankara

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27 July 2018

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27 July 2018

NYVAC: a highly attenuated strain of vaccinia virus

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27 July 2018

Infection of human dendritic cells with recombinant vaccinia virus MVA reveals general persistence of viral early transcription but distinct maturation-dependent cytopathogenicity

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24 September 2018

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Phase I clinical trial safety of DNA- and modified virus Ankara-vectored human immunodeficiency virus type 1 (HIV-1) vaccines administered alone and in a prime-boost regime to healthy HIV-1-uninfected volunteers

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24 September 2018

Protein kinase C modulates tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by targeting the apical events of death receptor signaling

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24 September 2018

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24 September 2018

Vaccinia virus strains Lister, USSR and Evans express soluble and cell-surface tumour necrosis factor receptors

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24 September 2018

Marker rescue of the host range restriction defects of modified vaccinia virus Ankara

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24 September 2018

The vaccinia virus E3L gene product interacts with both the regulatory and the substrate binding regions of PKR: implications for PKR autoregulation

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24 September 2018

A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell.

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24 September 2018

Phase I/IIa safety, immunogenicity, and efficacy trial of NYVAC-Pf7, a pox-vectored, multiantigen, multistage vaccine candidate for Plasmodium falciparum malaria.

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24 September 2018

Multiple immunizations with attenuated poxvirus HIV type 2 recombinants and subunit boosts required for protection of rhesus macaques.

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24 September 2018

Vaccinia virus encodes a soluble type I interferon receptor of novel structure and broad species specificity

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24 September 2018

Inhibition of the complement cascade by the major secretory protein of vaccinia virus

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24 September 2018

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The interferon-induced double-stranded RNA-activated protein kinase induces apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17537851

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ligand-independent anti-oncogenic activity of the alpha subunit of the type I interferon receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/17537851

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Monocyte-derived dendritic cells are permissive to the complete replicative cycle of human cytomegalovirus

1 reference

https://pubmed.ncbi.nlm.nih.gov/17537851

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kinetics of dendritic cell activation: impact on priming of TH1, TH2 and nonpolarized T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17537851

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/JVI.00444-07

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17537851%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17537851%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17537851%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

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