Tumor suppressor PDCD4 represses internal ribosome entry site-mediated translation of antiapoptotic proteins and is regulated by S6 kinase 2. (Q35943987)

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English	Tumor suppressor PDCD4 represses internal ribosome entry site-mediated translation of antiapoptotic proteins and is regulated by S6 kinase 2.	scientific article

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26 January 2020

Tumor suppressor PDCD4 represses internal ribosome entry site-mediated translation of antiapoptotic proteins and is regulated by S6 kinase 2 (English)

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26 January 2020

Stephen M. Lewis

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26 January 2020

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26 January 2020

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Urszula Liwak

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26 January 2020

Nehal Thakor

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26 January 2020

Lindsay E Jordan

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26 January 2020

Rajat Roy

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26 January 2020

Olivier E Pardo

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26 January 2020

Michael Seckl

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26 January 2020

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19 March 2012

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26 January 2020

Molecular and Cellular Biology

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26 January 2020

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10

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26 January 2020

1818-1829

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26 January 2020

IRES-mediated translation of cellular messenger RNA operates in eIF2α- independent manner during stress.

1 reference

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2 October 2017

Expression of truncated eukaryotic initiation factor 3e (eIF3e) resulting from integration of mouse mammary tumor virus (MMTV) causes a shift from cap-dependent to cap-independent translation

1 reference

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2 October 2017

Pdcd4 directly binds the coding region of c-myb mRNA and suppresses its translation

1 reference

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2 October 2017

Hallmarks of Cancer: The Next Generation

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2 October 2017

Cellular IRES-mediated translation: the war of ITAFs in pathophysiological states.

1 reference

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2 October 2017

RNA-binding protein HuR mediates cytoprotection through stimulation of XIAP translation.

1 reference

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2 October 2017

Functions and regulation of the 70kDa ribosomal S6 kinases.

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2 October 2017

Distinct 5' UTRs regulate XIAP expression under normal growth conditions and during cellular stress

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2 October 2017

eIF2alpha phosphorylation tips the balance to apoptosis during osmotic stress

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2 October 2017

Translational control in cancer.

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2 October 2017

The mechanism of eukaryotic translation initiation and principles of its regulation

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2 October 2017

NF45 functions as an IRES trans-acting factor that is required for translation of cIAP1 during the unfolded protein response

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2 October 2017

Regulation of XIAP translation and induction by MDM2 following irradiation

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2 October 2017

Bcl2 family proteins in carcinogenesis and the treatment of cancer.

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2 October 2017

hnRNP A1 regulates UV-induced NF-kappaB signalling through destabilization of cIAP1 mRNA.

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2 October 2017

PDCD4 inhibits translation initiation by binding to eIF4A using both its MA3 domains

1 reference

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2 October 2017

The eIF4G homolog DAP5/p97 supports the translation of select mRNAs during endoplasmic reticulum stress.

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2 October 2017

For IRES trans-acting factors, it is all about location.

1 reference

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2 October 2017

A search for structurally similar cellular internal ribosome entry sites.

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2 October 2017

Subcellular relocalization of a trans-acting factor regulates XIAP IRES-dependent translation.

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2 October 2017

An efficient tandem affinity purification procedure for interaction proteomics in mammalian cells

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2 October 2017

Structural basis for inhibition of translation by the tumor suppressor Pdcd4.

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2 October 2017

S6K1- and betaTRCP-mediated degradation of PDCD4 promotes protein translation and cell growth

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2 October 2017

Searching for IRES

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2 October 2017

FGF-2 protects small cell lung cancer cells from apoptosis through a complex involving PKCepsilon, B-Raf and S6K2

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2 October 2017

Impaired control of IRES-mediated translation in X-linked dyskeratosis congenita

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2 October 2017

Internal ribosome entry site-mediated translation of Apaf-1, but not XIAP, is regulated during UV-induced cell death.

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2 October 2017

A second look at cellular mRNA sequences said to function as internal ribosome entry sites

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2 October 2017

Eukaryotic translation initiation factor 4GI and p97 promote cellular internal ribosome entry sequence-driven translation

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2 October 2017

Translational control in stress and apoptosis

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2 October 2017

A novel function of the MA-3 domains in transformation and translation suppressor Pdcd4 is essential for its binding to eukaryotic translation initiation factor 4A

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2 October 2017

Demonstrating internal ribosome entry sites in eukaryotic mRNAs using stringent RNA test procedures

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2 October 2017

Characterization of programmed cell death 4 in multiple human cancers reveals a novel enhancer of drug sensitivity

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2 October 2017

Translational induction of the inhibitor of apoptosis protein HIAP2 during endoplasmic reticulum stress attenuates cell death and is mediated via an inducible internal ribosome entry site element.

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2 October 2017

Fibroblast growth factor 2-mediated translational control of IAPs blocks mitochondrial release of Smac/DIABLO and apoptosis in small cell lung cancer cells

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2 October 2017

Loss of PDCD4 expression in human lung cancer correlates with tumour progression and prognosis

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2 October 2017

The internal ribosome entry site-mediated translation of antiapoptotic protein XIAP is modulated by the heterogeneous nuclear ribonucleoproteins C1 and C2.

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2 October 2017

The transformation suppressor Pdcd4 is a novel eukaryotic translation initiation factor 4A binding protein that inhibits translation

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2 October 2017

Cloning and characterization of the rat homologues of the Inhibitor of Apoptosis protein 1, 2, and 3 genes

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2 October 2017

Fibroblast growth factor-2 induces translational regulation of Bcl-XL and Bcl-2 via a MEK-dependent pathway: correlation with resistance to etoposide-induced apoptosis

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2 October 2017

Functional characterization of the X-linked inhibitor of apoptosis (XIAP) internal ribosome entry site element: role of La autoantigen in XIAP translation

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2 October 2017

A new internal-ribosome-entry-site motif potentiates XIAP-mediated cytoprotection

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2 October 2017

The transformation suppressor protein Pdcd4 shuttles between nucleus and cytoplasm and binds RNA.

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11 July 2018

Pdcd4 suppresses tumor phenotype in JB6 cells by inhibiting AP-1 transactivation.

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11 July 2018

Use of Escherichiu coli (E. coli) lacZ (β-Galactosidase) as a Reporter Gene.

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24 September 2018

Translational upregulation of X-linked inhibitor of apoptosis (XIAP) increases resistance to radiation induced cell death.

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24 September 2018

Regulation of vascular endothelial growth factor (VEGF) expression is mediated by internal initiation of translation and alternative initiation of transcription.

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24 September 2018

XIAP, the guardian angel

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https://pubmed.ncbi.nlm.nih.gov/22431522

12 December 2020

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10.1128/MCB.06317-11

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26 January 2020

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26 January 2020

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26 January 2020

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