Preclinical evaluation of a genetically engineered herpes simplex virus expressing interleukin-12 (Q35943736)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22379082%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

title

Preclinical evaluation of a genetically engineered herpes simplex virus expressing interleukin-12 (English)

1 reference

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24 January 2020

10

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24 January 2020

Samuel Cartner

11

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24 January 2020

author name string

James M Markert

1

1 reference

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24 January 2020

James J Cody

2

1 reference

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24 January 2020

Jacqueline N Parker

3

1 reference

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24 January 2020

Jennifer M Coleman

4

1 reference

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24 January 2020

Kathleen H Price

5

1 reference

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24 January 2020

Earl R Kern

6

1 reference

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24 January 2020

Debra C Quenelle

7

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24 January 2020

Alfred D Lakeman

8

1 reference

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24 January 2020

Trenton R Schoeb

9

1 reference

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24 January 2020

G Yancey Gillespie

12

1 reference

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24 January 2020

Richard J Whitley

13

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24 January 2020

language of work or name

English

0 references

publication date

29 February 2012

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24 January 2020

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24 January 2020

volume

86

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24 January 2020

page(s)

5304-5313

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24 January 2020

issue

9

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Current concepts and management of glioblastoma

24 January 2020

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2 October 2017

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Serial passage through human glioma xenografts selects for a Deltagamma134.5 herpes simplex virus type 1 mutant that exhibits decreased neurotoxicity and prolongs survival of mice with experimental brain tumors

2 October 2017

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2 October 2017

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2 October 2017

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Increased efficacy of an interleukin-12-secreting herpes simplex virus in a syngeneic intracranial murine glioma model

2 October 2017

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2 October 2017

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HSV1716 injection into the brain adjacent to tumour following surgical resection of high-grade glioma: safety data and long-term survival

2 October 2017

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Angiogenesis inhibition by an oncolytic herpes virus expressing interleukin 12.

2 October 2017

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Oncolytic viruses: clinical applications as vectors for the treatment of malignant gliomas

2 October 2017

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The potential for efficacy of the modified (ICP 34.5(-)) herpes simplex virus HSV1716 following intratumoural injection into human malignant glioma: a proof of principle study

2 October 2017

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2 October 2017

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Conditionally replicating herpes simplex virus mutant, G207 for the treatment of malignant glioma: results of a phase I trial

2 October 2017

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Toxicity evaluation of replication-competent herpes simplex virus (ICP 34.5 null mutant 1716) in patients with recurrent malignant glioma

2 October 2017

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Engineered herpes simplex virus expressing IL-12 in the treatment of experimental murine brain tumors

2 October 2017

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2 October 2017

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Attenuated, replication-competent herpes simplex virus type 1 mutant G207: safety evaluation of intracerebral injection in nonhuman primates.

2 October 2017

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Treatment of intracranial gliomas in immunocompetent mice using herpes simplex viruses that express murine interleukins

2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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Comparison of genetically engineered herpes simplex viruses for the treatment of brain tumors in a scid mouse model of human malignant glioma

2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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Herpes simplex virus type 1 deletion variants 1714 and 1716 pinpoint neurovirulence-related sequences in Glasgow strain 17+ between immediate early gene 1 and the 'a' sequence

2 October 2017

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Patient tumor EGFR and PDGFRA gene amplifications retained in an invasive intracranial xenograft model of glioblastoma multiforme

2 October 2017

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11 July 2018

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Reduction and elimination of encephalitis in an experimental glioma therapy model with attenuated herpes simplex mutants that retain susceptibility to acyclovir

11 July 2018

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The herpes simplex virus type 1 strain 17 open reading frame RL1 encodes a polypeptide of apparent M(r) 37K equivalent to ICP34.5 of herpes simplex virus type 1 strain F.

11 July 2018

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Treatment of human malignant meningiomas by G207, a replication-competent multimutated herpes simplex virus 1.

11 July 2018

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Experimental herpes simplex infection in the owl monkey.

11 July 2018

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Mapping of herpes simplex virus-1 neurovirulence to gamma 134.5, a gene nonessential for growth in culture

11 July 2018

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A microtiter virus yield reduction assay for the evaluation of antiviral compounds against human cytomegalovirus and herpes simplex virus.

11 July 2018

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Experimental Therapy of Human Glioma by Means of a Genetically Engineered Virus Mutant

11 July 2018

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"Armed" oncolytic herpes simplex viruses for brain tumor therapy

11 July 2018

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Oncolytic herpes simplex virus type-1 therapy in a highly infiltrative animal model of human glioblastoma

24 September 2018

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Use of an orthotopic xenograft model for assessing the effect of epidermal growth factor receptor amplification on glioblastoma radiation response.

24 September 2018

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Profiling penciclovir susceptibility and prevalence of resistance of herpes simplex virus isolates across eleven clinical trials

24 September 2018

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Viral shedding and biodistribution of G207, a multimutated, conditionally replicating herpes simplex virus type 1, after intracerebral inoculation in aotus.

24 September 2018

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Evaluation of ganciclovir-mediated enhancement of the antitumoral effect in oncolytic, multimutated herpes simplex virus type 1 (G207) therapy of brain tumors

24 September 2018

1 reference

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Corticosteroid administration does not affect viral oncolytic activity, but inhibits antitumor immunity in replication-competent herpes simplex virus tumor therapy.

24 September 2018

1 reference

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Systemic antitumor immunity in experimental brain tumor therapy using a multimutated, replication-competent herpes simplex virus

24 September 2018

1 reference

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Therapeutic efficiency and safety of a second-generation replication-conditional HSV1 vector for brain tumor gene therapy.

24 September 2018

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Selective vulnerability of mouse CNS neurons to latent infection with a neuroattenuated herpes simplex virus-1.

24 September 2018

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Herpes simplex virus genomes in human nervous system tissue analyzed by polymerase chain reaction

24 September 2018

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Antigen-specific humoral and cellular immune responses can be modulated in rhesus macaques through the use of IFN-gamma, IL-12, or IL-18 gene adjuvants

24 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22379082

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/JVI.06998-11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22379082%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22379082%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

1 reference