Sustained release of the CCR5 inhibitors CMPD167 and maraviroc from vaginal rings in rhesus macaques (Q35941408)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22330914%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

title

Sustained release of the CCR5 inhibitors CMPD167 and maraviroc from vaginal rings in rhesus macaques (English)

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22 January 2020

1

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22 January 2020

Ian Major

8

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22 January 2020

9

Robin J Shattock

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22 January 2020

10

Per Johan Klasse

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22 January 2020

15

John P Moore

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22 January 2020

author name string

Ronald S Veazey

2

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22 January 2020

Leslie Geer

3

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22 January 2020

Deborah Lowry

4

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22 January 2020

Susan M Fetherston

5

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22 January 2020

Diarmaid J Murphy

6

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22 January 2020

Peter Boyd

7

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22 January 2020

Lara A Doyle

11

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22 January 2020

Kelsi K Rasmussen

12

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22 January 2020

Laurie Goldman

13

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22 January 2020

Thomas J Ketas

14

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22 January 2020

language of work or name

English

0 references

publication date

13 February 2012

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22 January 2020

number of pages

8

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Antimicrobial Agents and Chemotherapy

inferred from page(s)

published in

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22 January 2020

volume

56

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22 January 2020

issue

5

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22 January 2020

page(s)

2251-2258

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Non-aqueous silicone elastomer gels as a vaginal microbicide delivery system for the HIV-1 entry inhibitor maraviroc.

22 January 2020

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2 October 2017

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Delay of simian human immunodeficiency virus infection and control of viral replication in vaccinated macaques challenged in the presence of a topical microbicide

2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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Protection of rhesus macaques from vaginal infection by vaginally delivered maraviroc, an inhibitor of HIV-1 entry via the CCR5 co-receptor

2 October 2017

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HIV, transmitted drug resistance, and the paradox of preexposure prophylaxis

2 October 2017

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Identification of rhesus macaque genital microbiota by 16S pyrosequencing shows similarities to human bacterial vaginosis: implications for use as an animal model for HIV vaginal infection

2 October 2017

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A pièce de resistance: how HIV-1 escapes small molecule CCR5 inhibitors

2 October 2017

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Whither or wither microbicides?

2 October 2017

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Reviews of anti-infective agents: maraviroc: the first of a new class of antiretroviral agents

2 October 2017

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Antiretroviral drug-based microbicides to prevent HIV-1 sexual transmission

2 October 2017

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Which topical microbicides for blocking HIV-1 transmission will work in the real world?

2 October 2017

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Microbicides and other topical strategies to prevent vaginal transmission of HIV.

2 October 2017

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Microbicides to prevent HIV transmission: overcoming obstacles to chemical barrier protection

2 October 2017

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Molecular cloning and radioligand binding characterization of the chemokine receptor CCR5 from rhesus macaque and human

2 October 2017

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Small-molecule antagonists of CCR5 and CXCR4: a promising new class of anti-HIV-1 drugs

2 October 2017

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Inhibiting sexual transmission of HIV-1 infection

2 October 2017

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Microbicides: a new approach to preventing HIV and other sexually transmitted infections

2 October 2017

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Considerations and development of topical microbicides to inhibit the sexual transmission of HIV.

2 October 2017

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2 October 2017

A vaginal fluid simulant

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Potentiometric determination of dissociation constants

2 October 2017

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Synergy against drug-resistant HIV-1 with the microbicide antiretrovirals, dapivirine and tenofovir, in combination

2 October 2017

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The temporal relationship between vaginal fluid volumes obtained with the Rovumeter vaginal aspirator and the fertile phase of the cycle.

11 July 2018

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Protection of macaques from vaginal SHIV challenge by vaginally delivered inhibitors of virus-cell fusion

11 July 2018

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24 September 2018

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Long-term, controlled release of the HIV microbicide TMC120 from silicone elastomer vaginal rings.

24 September 2018

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24 September 2018

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Influence of silicone elastomer solubility and diffusivity on the in vitro release of drugs from intravaginal rings.

24 September 2018

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Prevention of virus transmission to macaque monkeys by a vaginally applied monoclonal antibody to HIV-1 gp120.

24 September 2018

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Progesterone implants enhance SIV vaginal transmission and early virus load

24 September 2018

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Turning the Tide Against HIV

24 September 2018

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Pharmacokinetic study of different doses of Depo Provera

14 November 2018

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12 December 2020

Estrogens and the urogenital tract. Studies on steroid hormone receptors and a clinical study on a new estradiol-releasing vaginal ring

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12 December 2020

pH-metric log P. 4. Comparison of partition coefficients determined by HPLC and potentiometric methods to literature values

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12 December 2020

Entry inhibitor-based microbicides are active in vitro against HIV-1 isolates from multiple genetic subtypes

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12 December 2020

Influence of the Normal Menstrual Cycle on Vaginal Tissue, Discharge, and Microflora

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12 December 2020

Depomedroxyprogesterone-induced hypoestrogenism and changes in vaginal flora and epithelium

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12 December 2020

Development and evaluation of a vaginal ring device for sustained delivery of HIV microbicides to non-human primates

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12 December 2020

Safety and pharmacokinetics of dapivirine delivery from matrix and reservoir intravaginal rings to HIV-negative women

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12 December 2020

When do minority drug-resistant HIV-1 variants have a major clinical impact?

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12 December 2020

Immunization with HIV-1 gp41 Subunit Virosomes Induces Mucosal Antibodies Protecting Nonhuman Primates against Vaginal SHIV Challenges

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12 December 2020

Identifiers

DOI

10.1128/AAC.05810-11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22330914%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22330914%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

1 reference