The enterohepatic nuclear receptors are major regulators of the enterohepatic circulation of bile salts (Q35932368)

11 August 2017

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title

The enterohepatic nuclear receptors are major regulators of the enterohepatic circulation of bile salts (English)

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11 August 2017

2

Johan Auwerx

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author name string

Sander M Houten

series ordinal

1

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PubMed ID

15513299

11 August 2017

language of work or name

English

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publication date

1 January 2004

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11 August 2017

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11 August 2017

36

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11 August 2017

7

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11 August 2017

482-491

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Bile acid regulation of gene expression: roles of nuclear hormone receptors.

11 August 2017

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018790

The enzymes, regulation, and genetics of bile acid synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018790

Down-regulation of cholesterol 7alpha-hydroxylase (CYP7A1) gene expression by bile acids in primary rat hepatocytes is mediated by the c-Jun N-terminal kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018790

Bile Acid Regulation of C/EBPβ, CREB, and c-Jun Function, via the Extracellular Signal-Regulated Kinase and c-Jun NH2-Terminal Kinase Pathways, Modulates the Apoptotic Response of Hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018790

Identification of a nuclear receptor for bile acids

21 January 2018

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https://api.crossref.org/works/10.1080%2F07853890410018790

Bile acids: natural ligands for an orphan nuclear receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018790

Identification of a nuclear receptor that is activated by farnesol metabolites

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018790

Generation of multiple farnesoid-X-receptor isoforms through the use of alternative promoters

21 January 2018

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https://api.crossref.org/works/10.1080%2F07853890410018790

Natural structural variants of the nuclear receptor farnesoid X receptor affect transcriptional activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018790

Structural basis for bile acid binding and activation of the nuclear receptor FXR

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018790

Identification of farnesoid X receptor beta as a novel mammalian nuclear receptor sensing lanosterol

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018790

Farnesoid X Receptor Regulates Bile Acid-Amino Acid Conjugation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018790

Dehydroepiandrosterone sulfotransferase gene induction by bile acid activated farnesoid X receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018790

Mammalian ABC transporters in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018790

Disrupted bile acid homeostasis reveals an unexpected interaction among nuclear hormone receptors, transporters, and cytochrome P450.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018790

Farnesoid X Receptor Activates Transcription of the Phospholipid Pump MDR3

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018790

Regulation of multidrug resistance-associated protein 2 (ABCC2) by the nuclear receptors pregnane X receptor, farnesoid X-activated receptor, and constitutive androstane receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018790

A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018790

Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018790

Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018790

Loss of nuclear receptor SHP impairs but does not eliminate negative feedback regulation of bile acid synthesis

21 January 2018

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https://api.crossref.org/works/10.1080%2F07853890410018790

Redundant pathways for negative feedback regulation of bile acid production

21 January 2018

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https://api.crossref.org/works/10.1080%2F07853890410018790

The orphan nuclear receptor, shp, mediates bile acid-induced inhibition of the rat bile acid transporter, ntcp

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018790

Liver receptor homologue-1 mediates species- and cell line-specific bile acid-dependent negative feedback regulation of the apical sodium-dependent bile acid transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018790

Alternative splicing of the rat sodium/bile acid transporter changes its cellular localization and transport properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018790

Enterohepatic circulation of bile salts in farnesoid X receptor-deficient mice: efficient intestinal bile salt absorption in the absence of ileal bile acid-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018790

Human kininogen gene is transactivated by the farnesoid X receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018790

Blood pressure regulation by the kallikrein-kinin system

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018790

Definition of a novel growth factor-dependent signal cascade for the suppression of bile acid biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018790

Progressive familial intrahepatic cholestasis, type 1, is associated with decreased farnesoid X receptor activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018790

Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018790

Differential regulation of rat and human CYP7A1 by the nuclear oxysterol receptor liver X receptor-alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018790

Transcriptional regulation of the human sterol 12alpha-hydroxylase gene (CYP8B1): roles of heaptocyte nuclear factor 4alpha in mediating bile acid repression

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018790

An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018790

Vitamin D receptor as an intestinal bile acid sensor

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018790

Lithocholic acid decreases expression of bile salt export pump through farnesoid X receptor antagonist activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018790

Impaired localisation and transport function of canalicular Bsep in taurolithocholate induced cholestasis in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018790

Induction of rat organic anion transporting polypeptide 2 by pregnenolone-16alpha-carbonitrile is via interaction with pregnane X receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018790

Complementary roles of farnesoid X receptor, pregnane X receptor, and constitutive androstane receptor in protection against bile acid toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018790

Interactions between hepatic Mrp4 and Sult2a as revealed by the constitutive androstane receptor and Mrp4 knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018790

A novel constitutive androstane receptor-mediated and CYP3A-independent pathway of bile acid detoxification

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018790

Regulation of a xenobiotic sulfonation cascade by nuclear pregnane X receptor (PXR).

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018790

The negative effects of bile acids and tumor necrosis factor-alpha on the transcription of cholesterol 7alpha-hydroxylase gene (CYP7A1) converge to hepatic nuclear factor-4: a novel mechanism of feedback regulation of bile acid synthesis mediated by

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018790

6alpha-ethyl-chenodeoxycholic acid (6-ECDCA), a potent and selective FXR agonist endowed with anticholestatic activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018790

Identification of a chemical tool for the orphan nuclear receptor FXR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018790

Hepatoprotection by the farnesoid X receptor agonist GW4064 in rat models of intra- and extrahepatic cholestasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018790

10.1080/07853890410018790

21 January 2018

Identifiers

DOI

1 reference

11 August 2017

1 reference

PubMed ID

15513299