Platelet-derived growth factor-C (PDGF-C) activation by serine proteases: implications for breast cancer progression (Q35929823)

11 August 2017

Platelet-derived growth factor-C (PDGF-C) activation by serine proteases: implications for breast cancer progression (English)

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11 August 2017

5

Hyeong-Reh Choi Kim

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11 August 2017

Newton J Hurst

1

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11 August 2017

Abdo J Najy

series ordinal

2

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11 August 2017

Carolyn V Ustach

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3

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11 August 2017

Lisa Movilla

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4

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11 August 2017

language of work or name

English

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publication date

1 February 2012

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11 August 2017

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11 August 2017

441

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11 August 2017

3

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11 August 2017

909-918

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describes a project that uses

11 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3342761/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Paracrine signaling by platelet-derived growth factor-CC promotes tumor growth by recruitment of cancer-associated fibroblasts

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PDGF-C mediates the angiogenic and tumorigenic properties of fibroblasts associated with tumors refractory to anti-VEGF treatment

2 October 2017

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Plasmin is the major protease responsible for processing PDGF-C in the vitreous of patients with proliferative vitreoretinopathy

2 October 2017

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Demethylation-linked activation of urokinase plasminogen activator is involved in progression of prostate cancer

2 October 2017

1 reference

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Streptokinase--the drug of choice for thrombolytic therapy

2 October 2017

1 reference

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Autocrine PDGFR signaling promotes mammary cancer metastasis

2 October 2017

1 reference

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Identification of biomarkers of human pancreatic adenocarcinomas by expression profiling and validation with gene expression analysis in endoscopic ultrasound-guided fine needle aspiration samples

2 October 2017

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Delineation of matriptase protein expression by enzymatic gene trapping suggests diverging roles in barrier function, hair formation, and squamous cell carcinogenesis

2 October 2017

1 reference

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Tissue-type plasminogen activator is upregulated in metastatic breast cancer cells exposed to insulin-like growth factor-I.

2 October 2017

1 reference

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Expression of serine protease SNC19/matriptase and its inhibitor hepatocyte growth factor activator inhibitor type 1 in normal and malignant tissues of gastrointestinal tract

2 October 2017

1 reference

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Overexpression of platelet-derived growth factor receptor alpha in breast cancer is associated with tumour progression

2 October 2017

1 reference

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Platelet-derived growth factor D is activated by urokinase plasminogen activator in prostate carcinoma cells

2 October 2017

1 reference

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Structural requirements for activation of latent platelet-derived growth factor CC by tissue plasminogen activator.

2 October 2017

1 reference

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Transmembrane serine protease TADG-15 (ST14/Matriptase/MT-SP1): expression and prognostic value in ovarian cancer.

2 October 2017

1 reference

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Tissue plasminogen activator is a potent activator of PDGF-CC

2 October 2017

1 reference

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uPAR: a versatile signalling orchestrator

2 October 2017

1 reference

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Platelet-derived growth factor-B and -C and active alpha-receptors in medulloblastoma cells.

2 October 2017

1 reference

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Dominant negative PDGF-C inhibits growth of Ewing family tumor cell lines

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3342761

PDGF-D is a specific, protease-activated ligand for the PDGF beta-receptor

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3342761

PDGF-C is an EWS/FLI induced transforming growth factor in Ewing family tumors

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3342761

The complexities of breast cancer desmoplasia

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3342761

Platelet-derived growth factor C (PDGF-C), a novel growth factor that binds to PDGF alpha and beta receptor

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3342761

Matriptase and HAI-1 are expressed by normal and malignant epithelial cells in vitro and in vivo

2 October 2017

1 reference

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Ovarian tumor cells express a transmembrane serine protease: a potential candidate for early diagnosis and therapeutic intervention

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3342761

Activation of hepatocyte growth factor and urokinase/plasminogen activator by matriptase, an epithelial membrane serine protease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3342761

Rapid and general profiling of protease specificity by using combinatorial fluorogenic substrate libraries

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3342761

Cellular localization of membrane-type serine protease 1 and identification of protease-activated receptor-2 and single-chain urokinase-type plasminogen activator as substrates

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3342761

PDGF-C is a new protease-activated ligand for the PDGF alpha-receptor

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3342761

Reverse biochemistry: use of macromolecular protease inhibitors to dissect complex biological processes and identify a membrane-type serine protease in epithelial cancer and normal tissue

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3342761

Molecular cloning of cDNA for matriptase, a matrix-degrading serine protease with trypsin-like activity

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3342761

Evidence for distinct signaling properties and biological responses induced by the PDGF receptor alpha and beta subtypes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3342761

Cloning and chromosomal mapping of a gene isolated from thymic stromal cells encoding a new mouse type II membrane serine protease, epithin, containing four LDL receptor modules and two CUB domains

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3342761

Distinguishing the specificities of closely related proteases. Role of P3 in substrate and inhibitor discrimination between tissue-type plasminogen activator and urokinase.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3342761

The 2.3 A crystal structure of the catalytic domain of recombinant two-chain human tissue-type plasminogen activator

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3342761

The crystal structure of the catalytic domain of human urokinase-type plasminogen activator

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3342761

Polypeptide growth factors: roles in normal and abnormal cell growth

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3342761

Use of a hybrid vaccinia virus-T7 RNA polymerase system for expression of target genes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3342761

The biology of platelet-derived growth factor

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3342761

Basic and clinical aspects of fibrinolysis and thrombolysis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3342761

Identification of degradome components associated with prostate cancer progression by expression analysis of human prostatic tissues

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3342761

Tissue plasminogen activator expression in meningiomas and glioblastomas.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3342761

Tissue-type plasminogen activator (tPA) in breast cancer: relationship with clinicopathological parameters and prognostic significance

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3342761

Characterization of matriptase expression in normal human tissues

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3342761

Platelet-derived growth factor (PDGF) autocrine signaling regulates survival and mitogenic pathways in glioblastoma cells: evidence that the novel PDGF-C and PDGF-D ligands may play a role in the development of brain tumors.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3342761

Human breast carcinoma desmoplasia is PDGF initiated.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3342761

Optimal subsite occupancy and design of a selective inhibitor of urokinase.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3342761

Urokinase plasminogen activator and plasminogen activator inhibitor type-1 in nonsmall-cell lung cancer: relation to prognosis and angiogenesis

24 September 2018

1 reference

12 December 2020

Urokinase plasminogen activator system gene expression is increased in human breast carcinoma and its bone metastases--a comparison of normal breast tissue, non-invasive and invasive carcinoma and osseous metastases

1 reference

12 December 2020

Substrate specificity of tissue-type and urokinase-type plasminogen activators

1 reference

12 December 2020

Identification and characterization of a novel matrix-degrading protease from hormone-dependent human breast cancer cells

1 reference

12 December 2020

Expression and localization of elements of the plasminogen activation system in benign breast disease and breast cancers

1 reference

12 December 2020

Expression of platelet-derived growth factor B-chain and the platelet-derived growth factor receptor beta subunit in human breast tissue and breast carcinoma

1 reference

12 December 2020

Distinct mechanisms contribute to stringent substrate specificity of tissue-type plasminogen activator

1 reference

12 December 2020

Identifiers

DOI

10.1042/BJ20111020

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11 August 2017

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11 August 2017

PubMed publication ID

22035541

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