Properties of the human Cdc45/Mcm2-7/GINS helicase complex and its action with DNA polymerase epsilon in rolling circle DNA synthesis. (Q35924967)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22474384%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

title

Properties of the human Cdc45/Mcm2-7/GINS helicase complex and its action with DNA polymerase epsilon in rolling circle DNA synthesis (English)

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27 January 2020

1

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27 January 2020

author name string

Wiebke Chemnitz Galal

2

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27 January 2020

Andrea Farina

3

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27 January 2020

Inger Tappin

4

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27 January 2020

Jerard Hurwitz

5

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27 January 2020

language of work or name

English

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publication date

2 April 2012

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Proceedings of the National Academy of Sciences of the United States of America

27 January 2020

published in

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27 January 2020

volume

109

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27 January 2020

page(s)

6042-6047

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27 January 2020

issue

16

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Characterization of DNA primase complex isolated from the archaeon, Thermococcus kodakaraensis

27 January 2020

cites work

1 reference

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Studies on human DNA polymerase epsilon and GINS complex and their role in DNA replication

2 October 2017

1 reference

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The structural basis for MCM2-7 helicase activation by GINS and Cdc45.

2 October 2017

1 reference

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Regulation of the initiation step of DNA replication by cyclin-dependent kinases.

2 October 2017

1 reference

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The Saccharomyces cerevisiae Mcm6/2 and Mcm5/3 ATPase active sites contribute to the function of the putative Mcm2-7 'gate'.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3341058

Treslin collaborates with TopBP1 in triggering the initiation of DNA replication

2 October 2017

1 reference

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A double-hexameric MCM2-7 complex is loaded onto origin DNA during licensing of eukaryotic DNA replication

2 October 2017

1 reference

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Concerted loading of Mcm2-7 double hexamers around DNA during DNA replication origin licensing

2 October 2017

1 reference

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Assembly of the Cdc45-Mcm2-7-GINS complex in human cells requires the Ctf4/And-1, RecQL4, and Mcm10 proteins

2 October 2017

1 reference

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The Mcm2-7 complex has in vitro helicase activity.

2 October 2017

1 reference

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Cell cycle regulation of DNA replication.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3341058

Yeast DNA polymerase epsilon participates in leading-strand DNA replication

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3341058

Phosphorylation of Sld2 and Sld3 by cyclin-dependent kinases promotes DNA replication in budding yeast.

2 October 2017

1 reference

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CDK-dependent phosphorylation of Sld2 and Sld3 initiates DNA replication in budding yeast

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3341058

Isolation of the Cdc45/Mcm2-7/GINS (CMG) complex, a candidate for the eukaryotic DNA replication fork helicase

2 October 2017

1 reference

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Distinct roles for Sld3 and GINS during establishment and progression of eukaryotic DNA replication forks

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3341058

GINS maintains association of Cdc45 with MCM in replisome progression complexes at eukaryotic DNA replication forks

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3341058

Dynamics of pre-replication complex proteins during the cell division cycle

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3341058

Mcm4,6,7 uses a "pump in ring" mechanism to unwind DNA by steric exclusion and actively translocate along a duplex.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3341058

Processive DNA helicase activity of the minichromosome maintenance proteins 4, 6, and 7 complex requires forked DNA structures

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3341058

The DNA replication fork in eukaryotic cells.

2 October 2017

1 reference

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Two DNA polymerases may be required for synthesis of the lagging DNA strand of simian virus 40.

2 October 2017

1 reference

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Synthesis of DNA by DNA polymerase epsilon in vitro

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3341058

Activation of the MCM2-7 helicase by association with Cdc45 and GINS proteins.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3341058

Localization of MCM2-7, Cdc45, and GINS to the site of DNA unwinding during eukaryotic DNA replication.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3341058

Substrate requirements for duplex DNA translocation by the eukaryal and archaeal minichromosome maintenance helicases

24 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22474384

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1203734109

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27 January 2020

0 references

1 reference

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27 January 2020

1 reference

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