Multiscale modeling of form and function (Q35924226)

11 August 2017

1 reference

title

Multiscale modeling of form and function (English)

1 reference

11 August 2017

Patrick O Humbert

2

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Adam J Engler

object named as

Adam J Engler

series ordinal

1

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Valerie M Weaver

series ordinal

4

object named as

Valerie M Weaver

1 reference

11 August 2017

Bernhard Wehrle-Haller

series ordinal

3

1 reference

PMCID

4527531

11 August 2017

language of work or name

English

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publication date

1 April 2009

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11 August 2017

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11 August 2017

324

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11 August 2017

5924

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11 August 2017

208-212

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Environmental sensing through focal adhesions

11 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527531

Mechanically activated integrin switch controls alpha5beta1 function

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527531

Stretching single talin rod molecules activates vinculin binding

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527531

The physical state of fibronectin matrix differentially regulates morphogenetic movements in vivo

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527531

Structure of a Complete Integrin Ectodomain in a Physiologic Resting State and Activation and Deactivation by Applied Forces

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527531

Traction stress in focal adhesions correlates biphasically with actin retrograde flow speed

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527531

Traction dynamics of filopodia on compliant substrates.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527531

Deregulation of scribble promotes mammary tumorigenesis and reveals a role for cell polarity in carcinoma

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527531

Polarity and differential inheritance--universal attributes of life?

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527531

Evolution of collagen-based adhesion systems.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527531

Evidence for the evolution of tenascin and fibronectin early in the chordate lineage

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527531

The Trichoplax genome and the nature of placozoans

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527531

Demosponge and sea anemone fibrillar collagen diversity reveals the early emergence of A/C clades and the maintenance of the modular structure of type V/XI collagens from sponge to human

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527531

Morphogen control of wing growth through the Fat signaling pathway.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527531

Involvement of Sib proteins in the regulation of cellular adhesion in Dictyostelium discoideum

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527531

Cell-cell adhesion in the cnidaria: insights into the evolution of tissue morphogenesis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527531

Unexpected diversity of cnidarian integrins: expression during coral gastrulation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527531

Fibronectin expression modulates mammary epithelial cell proliferation during acinar differentiation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527531

Distinct domains of the Candida albicans adhesin Eap1p mediate cell-cell and cell-substrate interactions

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527531

The genome of the choanoflagellate Monosiga brevicollis and the origin of metazoans

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527531

Role of polysaccharides in Pseudomonas aeruginosa biofilm development

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527531

The control of human mesenchymal cell differentiation using nanoscale symmetry and disorder

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527531

Planar cell polarity: one or two pathways?

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527531

2 October 2017

The echinoderm adhesome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527531

Matrix elasticity directs stem cell lineage specification

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527531

Of extracellular matrix, scaffolds, and signaling: tissue architecture regulates development, homeostasis, and cancer.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527531

An adhesion molecule in free-living Dictyostelium amoebae with integrin beta features.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527531

The mechanisms and dynamics of (alpha)v(beta)3 integrin clustering in living cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527531

Integrin-dependent actomyosin contraction regulates epithelial cell scattering.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527531

Tensional homeostasis and the malignant phenotype

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527531

Emergent patterns of growth controlled by multicellular form and mechanics

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527531

PINCH1 regulates cell-matrix and cell-cell adhesions, cell polarity and cell survival during the peri-implantation stage

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527531

Spatial distribution and functional significance of activated vinculin in living cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527531

The genome of the social amoeba Dictyostelium discoideum

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527531

The differential adhesion hypothesis: a direct evaluation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527531

Regulation of cell-cell adhesion during Dictyostelium development

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527531

Comparison of molecular mechanisms mediating cell contact phenomena in model developmental systems: an exploration of universality

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527531

The unicellular ancestry of animal development

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527531

Interplay of mechanical deformation and patterned gene expression in developing embryos.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527531

Mechanism of homophilic adhesion by the neural cell adhesion molecule: use of multiple domains and flexibility

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527531

Cell shape, cytoskeletal tension, and RhoA regulate stem cell lineage commitment

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527531

Genetic and epigenetic regulation of the FLO gene family generates cell-surface variation in yeast

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527531

Evolution of key cell signaling and adhesion protein families predates animal origins

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527531

Deciphering skeletal patterning: clues from the limb

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527531

How we are shaped: the biomechanics of gastrulation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527531

RPTP-alpha acts as a transducer of mechanical force on alphav/beta3-integrin-cytoskeleton linkages

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527531

Integrin-linked kinase (ILK) is required for polarizing the epiblast, cell adhesion, and controlling actin accumulation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527531

beta4 integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and malignant mammary epithelium

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527531

Matrix assembly, regulation, and survival functions of laminin and its receptors in embryonic stem cell differentiation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527531

Cell-cell adhesion via the ECM: integrin genetics in fly and worm

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527531

Fibronectin matrix composition and organization can regulate cell migration during amphibian development

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527531

Molecular evolution of integrins: genes encoding integrin beta subunits from a coral and a sponge

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527531

Reversion of the malignant phenotype of human breast cells in three-dimensional culture and in vivo by integrin blocking antibodies

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527531

Cell adhesion: the molecular basis of tissue architecture and morphogenesis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527531

Basement Membrane Proteins: Structure, Assembly, and Cellular Interactions

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527531

Normal genetically mosaic mice produced from malignant teratocarcinoma cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527531

Forced unfolding of proteins within cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527531

Mathematical modeling of planar cell polarity to understand domineering nonautonomy.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527531

On the origin of Metazoan adhesion receptors: cloning of integrin alpha subunit from the sponge Geodia cydonium

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527531

Synergistic roles for receptor occupancy and aggregation in integrin transmembrane function.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527531

Deletion of beta 1 integrins in mice results in inner cell mass failure and peri-implantation lethality

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527531

Tissue deformation modulates twist expression to determine anterior midgut differentiation in Drosophila embryos.

11 July 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1170107

Tensile forces govern germ-layer organization in zebrafish.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1170107

Expression of collagen and related growth factors in rat tendon and skeletal muscle in response to specific contraction types.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1170107

Evolution of the integrin alpha and beta protein families.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1170107

Paxillin is required for cell-substrate adhesion, cell sorting and slug migration during Dictyostelium development

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1170107

Dynamic control of positional information in the early Drosophila embryo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1170107

Mechanical asymmetry in the embryonic chick heart during looping.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1170107

EGF signaling and ommatidial rotation in the Drosophila eye.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1170107

Combinatorial signaling by the Frizzled/PCP and Egfr pathways during planar cell polarity establishment in the Drosophila eye.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1170107

Myosin-dependent junction remodelling controls planar cell intercalation and axis elongation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1170107

Imaging coexisting fluid domains in biomembrane models coupling curvature and line tension

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1170107

Spatial distribution of VEGF isoforms and chemotactic signals in the vicinity of a tumor

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1170107

Type IV collagens regulate BMP signalling in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1170107

Modeling and computational analysis of EGF receptor-mediated cell communication in Drosophila oogenesis.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527531

The architecture of life.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527531

Adherens junctions and β-catenin-mediated cell signalling in a non-metazoan organism

24 September 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1170107

Topobiology. An Introduction to Molecular Embryology. Gerald M. Edelman. Basic Books, New York, 1988. xvi, 240 pp., illus. $21.95

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19359578

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1126/SCIENCE.1170107

1 reference

11 August 2017

1 reference

11 August 2017

1 reference

PMCID

4527531