A Drosophila model for mito-nuclear diseases generated by an incompatible interaction between tRNA and tRNA synthetase (Q35923455)

11 August 2017

A Drosophila model for mito-nuclear diseases generated by an incompatible interaction between tRNA and tRNA synthetase (English)

1 reference

11 August 2017

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Marissa A Holmbeck

1

1 reference

11 August 2017

Julia R Donner

series ordinal

2

1 reference

11 August 2017

Eugenia Villa-Cuesta

series ordinal

3

1 reference

11 August 2017

David M Rand

series ordinal

4

1 reference

11 August 2017

language of work or name

1 reference

5 May 2015

1 reference

Disease Models & Mechanisms

11 August 2017

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11 August 2017

8

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11 August 2017

8

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11 August 2017

843-854

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Creative Commons Attribution 3.0 Unported

11 August 2017

start time

18 May 2021

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4527286/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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Phenotypic rescue of a Drosophila model of mitochondrial ANT1 disease.

2 October 2017

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Ret rescues mitochondrial morphology and muscle degeneration of Drosophila Pink1 mutants

2 October 2017

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Phenotypic variability and identification of novel YARS2 mutations in YARS2 mitochondrial myopathy, lactic acidosis and sideroblastic anaemia.

2 October 2017

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Mechanisms of skeletal muscle aging: insights from Drosophila and mammalian models

2 October 2017

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Mitochondrial cristae shape determines respiratory chain supercomplexes assembly and respiratory efficiency

2 October 2017

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Age-dependent dissociation of ATP synthase dimers and loss of inner-membrane cristae in mitochondria

2 October 2017

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Mitonuclear protein imbalance as a conserved longevity mechanism

2 October 2017

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Mitochondrial aminoacyl-tRNA synthetases in human disease

2 October 2017

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An Incompatibility between a mitochondrial tRNA and its nuclear-encoded tRNA synthetase compromises development and fitness in Drosophila

2 October 2017

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Human mitochondrial DNA: roles of inherited and somatic mutations

2 October 2017

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Mutations in the mitochondrial methionyl-tRNA synthetase cause a neurodegenerative phenotype in flies and a recessive ataxia (ARSAL) in humans

2 October 2017

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Human diseases with impaired mitochondrial protein synthesis

2 October 2017

1 reference

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Evolution meets disease: penetrance and functional epistasis of mitochondrial tRNA mutations

2 October 2017

1 reference

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The parkin mutant phenotype in the fly is largely rescued by metal-responsive transcription factor (MTF-1)

2 October 2017

1 reference

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Nuclear factors involved in mitochondrial translation cause a subgroup of combined respiratory chain deficiency

2 October 2017

1 reference

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Mitochondrial-nuclear epistasis affects fitness within species but does not contribute to fixed incompatibilities between species of Drosophila

2 October 2017

1 reference

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Mutation of the mitochondrial tyrosyl-tRNA synthetase gene, YARS2, causes myopathy, lactic acidosis, and sideroblastic anemia--MLASA syndrome

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527286

Mitochondrial translation and beyond: processes implicated in combined oxidative phosphorylation deficiencies

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527286

Human mitochondrial leucyl-tRNA synthetase corrects mitochondrial dysfunctions due to the tRNALeu(UUR) A3243G mutation, associated with mitochondrial encephalomyopathy, lactic acidosis, and stroke-like symptoms and diabetes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527286

Invertebrate models of age-related muscle degeneration

2 October 2017

1 reference

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Evolutionary implications of non-neutral mitochondrial genetic variation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527286

Genetic and environmental factors impact age-related impairment of negative geotaxis in Drosophila by altering age-dependent climbing speed

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527286

Overexpression of human mitochondrial valyl tRNA synthetase can partially restore levels of cognate mt-tRNAVal carrying the pathogenic C25U mutation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527286

Coordination of gene expression between organellar and nuclear genomes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527286

Pathogenic mitochondrial DNA mutations in protein-coding genes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527286

Involvement of the mitochondrial protein translocator component tim50 in growth, cell proliferation and the modulation of respiration in Drosophila

2 October 2017

1 reference

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Mitochondrial pathology and muscle and dopaminergic neuron degeneration caused by inactivation of Drosophila Pink1 is rescued by Parkin

2 October 2017

1 reference

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Cytonuclear coevolution: the genomics of cooperation

2 October 2017

1 reference

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Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin

2 October 2017

1 reference

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Nuclear-mitochondrial epistasis and drosophila aging: introgression of Drosophila simulans mtDNA modifies longevity in D. melanogaster nuclear backgrounds

2 October 2017

1 reference

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Human extraocular muscles in mitochondrial diseases: comparing chronic progressive external ophthalmoplegia with Leber's hereditary optic neuropathy.

2 October 2017

1 reference

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2 October 2017

Mitochondrial disorders

1 reference

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Drosophila parkin mutants have decreased mass and cell size and increased sensitivity to oxygen radical stress

2 October 2017

1 reference

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Mitochondrial signaling: the retrograde response

2 October 2017

1 reference

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Electron microscopic studies on the indirect flight muscles of Drosophila melanogaster. I. Structure of the myofibrils

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527286

Disorders of mitochondrial protein synthesis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527286

Mitochondrial respiratory-chain diseases

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527286

Mitochondrial pathology and apoptotic muscle degeneration in Drosophila parkin mutants

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527286

Increase of mitochondrial DNA in blood cells of patients with Leber's hereditary optic neuropathy with 11778 mutation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527286

Technical knockout, a Drosophila model of mitochondrial deafness

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527286

Energy metabolism during insect flight: biochemical design and physiological performance

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527286

2 October 2017

Genotypes and phenotypes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527286

Energy metabolism, enzymatic flux capacities, and metabolic flux rates in flying honeybees

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527286

Physiological properties of the dorsal longitudinal flight muscle and the tergal depressor of the trochanter muscle of Drosophila melanogaster

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527286

Biochemical adaptations for flight in the insect

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527286

A histochemical study of the muscles ofDrosophila melanogaster

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527286

The isolated carboxy-terminal domain of human mitochondrial leucyl-tRNA synthetase rescues the pathological phenotype of mitochondrial tRNA mutations in human cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527286

Human mitochondrial leucyl tRNA synthetase can suppress non cognate pathogenic mt-tRNA mutations

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527286

Genetic dissection of behavior / Seymour Benzer. - (1973)

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527286

Ultrastructural and molecular analyses of homozygous-viable Drosophila melanogaster muscle mutants indicate there is a complex pattern of myosin heavy-chain isoform distribution

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527286

Medicine. Mitochondrial replacement, evolution, and the clinic.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527286

A distinct mitochondrial myopathy, lactic acidosis and sideroblastic anemia (MLASA) phenotype associates with YARS2 mutations.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527286

A systems approach for decoding mitochondrial retrograde signaling pathways.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527286

Genetic architecture of metabolic rate: environment specific epistasis between mitochondrial and nuclear genes in an insect

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527286

Decreased mitochondrial superoxide levels and enhanced protection against paraquat in Drosophila melanogaster supplemented with Rhodiola rosea.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527286

Structure of dimeric ATP synthase from mitochondria: an angular association of monomers induces the strong curvature of the inner membrane.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527286

The minute genes in Drosophila and their molecular functions.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527286

Mitochondrial DNA and disease

24 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26035388

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A novel mutation in the mitochondrial tRNA(TYr) gene associated with exercise intolerance

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26035388

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1242/DMM.019323

1 reference

11 August 2017

1 reference

11 August 2017

1 reference