Brain fatty acid synthase activates PPARalpha to maintain energy homeostasis. (Q35921527)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17694178%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

title

Brain fatty acid synthase activates PPARalpha to maintain energy homeostasis (English)

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3 January 2020

0 references

3

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3 January 2020

Michael Wolfgang

8

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3 January 2020

Antonio Vidal-Puig

9

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3 January 2020

Clay F. Semenkovich

11

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3 January 2020

author name string

Manu V Chakravarthy

1

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3 January 2020

Yimin Zhu

2

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3 January 2020

Li Yin

4

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3 January 2020

David F Wozniak

5

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3 January 2020

Trey Coleman

6

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3 January 2020

Zhiyuan Hu

7

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3 January 2020

M Daniel Lane

10

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3 January 2020

language of work or name

English

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publication date

1 September 2007

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Journal of Clinical Investigation

3 January 2020

published in

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3 January 2020

volume

117

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3 January 2020

page(s)

2539-2552

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3 January 2020

issue

9

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Hypothalamic malonyl-CoA triggers mitochondrial biogenesis and oxidative gene expression in skeletal muscle: Role of PGC-1alpha.

3 January 2020

cites work

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Peroxisomal-proliferator-activated receptor alpha activates transcription of the rat hepatic malonyl-CoA decarboxylase gene: a key regulation of malonyl-CoA level

2 October 2017

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2 October 2017

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Oleylethanolamide regulates feeding and body weight through activation of the nuclear receptor PPAR-alpha

2 October 2017

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Inhibition of hypothalamic carnitine palmitoyltransferase-1 decreases food intake and glucose production

2 October 2017

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Fatty acid synthesis is essential in embryonic development: fatty acid synthase null mutants and most of the heterozygotes die in utero

2 October 2017

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PPAR alpha is necessary for the lipopenic action of hyperleptinemia on white adipose and liver tissue

2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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27 July 2018

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27 July 2018

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27 July 2018

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Tamoxifen-induced anorexia is associated with fatty acid synthase inhibition in the ventromedial nucleus of the hypothalamus and accumulation of malonyl-CoA.

27 July 2018

1 reference

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Effects of rimonabant on metabolic risk factors in overweight patients with dyslipidemia

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1937501

"New" hepatic fat activates PPARalpha to maintain glucose, lipid, and cholesterol homeostasis

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1937501

Pancreatic beta-cell lipoprotein lipase independently regulates islet glucose metabolism and normal insulin secretion

24 September 2018

1 reference

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Apoptotic neurodegeneration induced by ethanol in neonatal mice is associated with profound learning/memory deficits in juveniles followed by progressive functional recovery in adults

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1937501

A novel missense substitution (Val1483Ile) in the fatty acid synthase gene (FAS) is associated with percentage of body fat and substrate oxidation rates in nondiabetic Pima Indians

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1937501

C75 inhibits food intake by increasing CNS glucose metabolism

24 September 2018

1 reference

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Expression of FAS within hypothalamic neurons: a model for decreased food intake after C75 treatment

24 September 2018

1 reference

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Anxiogenic-like action of centrally administered glucagon-like peptide-1 in a punished drinking test

24 September 2018

1 reference

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Central administration of oleic acid inhibits glucose production and food intake

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1937501

Intracerebroventricularly administered corticotropin-releasing factor inhibits food intake and produces anxiety-like behaviour at very low doses in mice.

24 September 2018

1 reference

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Reduced food intake and body weight in mice treated with fatty acid synthase inhibitors.

24 September 2018

1 reference

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Analysis of the Cre-mediated recombination driven by rat insulin promoter in embryonic and adult mouse pancreas

24 September 2018

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Body mass index and mortality in men: evaluating the shape of the association

24 September 2018

1 reference

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Physiologic concentrations of glucose regulate fatty acid synthase activity in HepG2 cells by mediating fatty acid synthase mRNA stability

6 December 2018

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12 December 2020

Essential amino acids regulate fatty acid synthase expression through an uncharged transfer RNA-dependent mechanism

1 reference

12 December 2020

Fatty acid synthase (FAS): a target for cytotoxic antimetabolites in HL60 promyelocytic leukemia cells

1 reference

12 December 2020

Transcriptional regulation of fatty acid synthase gene by insulin/glucose, polyunsaturated fatty acid and leptin in hepatocytes and adipocytes in normal and genetically obese rats

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12 December 2020

Identifiers

DOI

10.1172/JCI31183

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17694178%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17694178%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

1 reference