Rapamycin selectively inhibits translation of mRNAs encoding elongation factors and ribosomal proteins (Q35917778)

11 August 2017

Rapamycin selectively inhibits translation of mRNAs encoding elongation factors and ribosomal proteins (English)

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11 August 2017

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N Terada

1

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11 August 2017

H R Patel

2

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11 August 2017

K Takase

3

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11 August 2017

K Kohno

4

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11 August 2017

A C Nairn

5

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11 August 2017

E W Gelfand

6

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11 August 2017

1 November 1994

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Proceedings of the National Academy of Sciences of the United States of America

11 August 2017

language of work or name

English

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published in

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11 August 2017

91

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11 August 2017

24

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11 August 2017

11477-11481

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Regulation of ribosomal protein mRNA content and translation in growth-stimulated mouse fibroblasts.

11 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45254

Failure of rapamycin to block proliferation once resting cells have entered the cell cycle despite inactivation of p70 S6 kinase

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45254

Identification of calmodulin-dependent protein kinase III and its major Mr 100,000 substrate in mammalian tissues

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45254

The transcriptionally active human ribosomal protein S17 gene

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45254

Amino acid sequence of mammalian elongation factor 2 deduced from the cDNA sequence: homology with GTP-binding proteins

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45254

Complete nucleotide sequence and characterization of the 5'-flanking region of mammalian elongation factor 2 gene.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45254

Insulin rapidly induces the biosynthesis of elongation factor 2.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45254

Isolation and characterization of the human chromosomal gene for polypeptide chain elongation factor-1 alpha

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45254

Regulation of the utilization of mRNA for eucaryotic elongation factor Tu in Friend erythroleukemia cells

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45254

Human cyclin A is adenovirus E1A-associated protein p60 and behaves differently from cyclin B.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45254

Oligopyrimidine tract at the 5' end of mammalian ribosomal protein mRNAs is required for their translational control

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45254

A comprehensive two-dimensional gel protein database of noncultured unfractionated normal human epidermal keratinocytes: Towards an integrated approach to the study of cell proliferation, differentiation and skin diseases

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45254

Rapamycin: FK506's fraternal twin or distant cousin?

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45254

A new human p34 protein kinase, CDK2, identified by complementation of a cdc28 mutation in Saccharomyces cerevisiae, is a homolog of Xenopus Eg1

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45254

MAP2 kinase and 70K S6 kinase lie on distinct signalling pathways

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45254

Distinct mechanisms for the activation of the RSK kinases/MAP2 kinase/pp90rsk and pp70-S6 kinase signaling systems are indicated by inhibition of protein synthesis

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45254

Rapamycin selectively inhibits interleukin-2 activation of p70 S6 kinase

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45254

Translational regulation of ribosomal protein synthesis in Xenopus cultured cells: mRNA relocation between polysomes and RNP during nutritional shifts

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45254

Rapamycin inhibits the phosphorylation of p70 S6 kinase in IL-2 and mitogen-activated human T cells

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45254

Rapamycin-induced inhibition of the 70-kilodalton S6 protein kinase

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45254

Interleukin 2 stimulation of p70 S6 kinase activity is inhibited by the immunosuppressant rapamycin

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45254

Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45254

Protein Phosphorylation in Translational Control

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45254

A regulatory cis element and a specific binding factor involved in the mitogenic control of murine ribosomal protein L32 translation

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45254

Rapamycin blocks cell cycle progression of activated T cells prior to events characteristic of the middle to late G1 phase of the cycle

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45254

Transcriptional and translational regulation of ribosomal protein formation during mouse myoblast differentiation

24 September 2018

1 reference

12 December 2020

Insulin stimulates the translation of ribosomal proteins and the transcription of rDNA in mouse myoblasts

1 reference

12 December 2020

The human ribosomal protein S6 gene: isolation, primary structure and location in chromosome 9

1 reference

12 December 2020

p70s6k function is essential for G1 progression

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12 December 2020

Translational repression of EF-1 alpha mRNA in vitro

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12 December 2020

Function and properties of aminoacyl transferase II. II. Subcellular distribution during asynchronous and synchronous growth

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12 December 2020

Identifiers

DOI

10.1073/PNAS.91.24.11477

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11 August 2017

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11 August 2017

PubMed publication ID

7972087

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