Invertebrate TRP proteins as functional models for mammalian channels (Q35916409)

11 August 2017

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title

Invertebrate TRP proteins as functional models for mammalian channels (English)

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11 August 2017

Joris Vriens

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Thomas Voets

object named as

Thomas Voets

series ordinal

3

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Bernd Nilius

series ordinal

5

object named as

Bernd Nilius

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11 August 2017

2

Grzegorz Owsianik

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11 August 2017

Guy Droogmans

4

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11 August 2017

1 December 2004

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11 August 2017

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11 August 2017

449

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11 August 2017

3

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11 August 2017

213-226

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https://scigraph.springernature.com/pub.10.1007/s00424-004-1314-1

11 August 2017

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cites work

The diversity in the vanilloid (TRPV) receptor family of ion channels

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12 December 2020

The TRP ion channel family.

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12 December 2020

Caenorhabditis elegans TRPV ion channel regulates 5HT biosynthesis in chemosensory neurons

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12 December 2020

Identification of four trp1 gene variants murine pancreatic beta-cells

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12 December 2020

Cloning of the gene encoding a novel integral membrane protein, mucolipidin-and identification of the two major founder mutations causing mucolipidosis type IV

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12 December 2020

Identification of a cold receptor reveals a general role for TRP channels in thermosensation

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12 December 2020

Loss of sex discrimination and male-male aggression in mice deficient for TRP2

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12 December 2020

OSM-9, a novel protein with structural similarity to channels, is required for olfaction, mechanosensation, and olfactory adaptation in Caenorhabditis elegans

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12 December 2020

The trp gene is essential for a light-activated Ca2+ channel in Drosophila photoreceptors.

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12 December 2020

Trp12, a novel Trp related protein from kidney

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12 December 2020

Trp-p8, a novel prostate-specific gene, is up-regulated in prostate cancer and other malignancies and shares high homology with transient receptor potential calcium channel proteins.

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12 December 2020

TRPV4 calcium entry channel: a paradigm for gating diversity.

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12 December 2020

TRP and the PDZ protein, INAD, form the core complex required for retention of the signalplex in Drosophila photoreceptor cells

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12 December 2020

Opposite thermosensor in fruitfly and mouse.

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12 December 2020

The epithelial calcium channels, TRPV5 & TRPV6: from identification towards regulation

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12 December 2020

Modulation of the epithelial Ca2+ channel ECaC by extracellular pH.

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12 December 2020

Identification and characterization of the single channel function of human mucolipin-1 implicated in mucolipidosis type IV, a disorder affecting the lysosomal pathway

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12 December 2020

Cell swelling, heat, and chemical agonists use distinct pathways for the activation of the cation channel TRPV4.

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12 December 2020

Molecular basis for species-specific sensitivity to "hot" chili peppers

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12 December 2020

TRPV3 is a calcium-permeable temperature-sensitive cation channel.

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12 December 2020

Hypomagnesemia with secondary hypocalcemia is caused by mutations in TRPM6, a new member of the TRPM gene family

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12 December 2020

OTRPC4, a nonselective cation channel that confers sensitivity to extracellular osmolarity

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12 December 2020

Pore properties and ionic block of the rabbit epithelial calcium channel expressed in HEK 293 cells

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12 December 2020

Polyunsaturated fatty acids activate the Drosophila light-sensitive channels TRP and TRPL.

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12 December 2020

New TRP channels in hearing and mechanosensation.

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12 December 2020

The genetics and physiology of polycystic kidney disease

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12 December 2020

A C. elegans sperm TRP protein required for sperm-egg interactions during fertilization

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12 December 2020

A flagellar polycystin-2 homolog required for male fertility in Drosophila

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12 December 2020

NompC TRP channel required for vertebrate sensory hair cell mechanotransduction.

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12 December 2020

Abnormal osmotic regulation in trpv4 -/- mice

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12 December 2020

Transducing touch in Caenorhabditis elegans

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12 December 2020

Mucolipidosis type IV: clinical spectrum and natural history.

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12 December 2020

PKD1 interacts with PKD2 through a probable coiled-coil domain

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12 December 2020

Calcium, calmodulin and cell cycle progression

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12 December 2020

Mucolipidosis type IV: novel MCOLN1 mutations in Jewish and non-Jewish patients and the frequency of the disease in the Ashkenazi Jewish population

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12 December 2020

Homo- and heterodimeric interactions between the gene products of PKD1 and PKD2

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12 December 2020

A family of calcium-permeable channels in the kidney: distinct roles in renal calcium handling

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12 December 2020

Identification of the gene causing mucolipidosis type IV.

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12 December 2020

LTRPC7 is a Mg.ATP-regulated divalent cation channel required for cell viability

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12 December 2020

Hypothesis: a helix of ankyrin repeats of the NOMPC-TRP ion channel is the gating spring of mechanoreceptors

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12 December 2020

Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells

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12 December 2020

Molecular characterization of the Drosophila trp locus: a putative integral membrane protein required for phototransduction

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12 December 2020

Noxious cold ion channel TRPA1 is activated by pungent compounds and bradykinin

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12 December 2020

Vanilloid and TRP channels: a family of lipid-gated cation channels.

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12 December 2020

Epithelial Ca2+ entry channels: transcellular Ca2+ transport and beyond

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12 December 2020

Regulation of vertebrate cellular Mg2+ homeostasis by TRPM7.

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12 December 2020

Neurobiology: social eating for stress

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12 December 2020

Requirement for the PDZ domain protein, INAD, for localization of the TRP store-operated channel to a signaling complex

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12 December 2020

TRP channels in Drosophila photoreceptors: the lipid connection

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12 December 2020

A TRP channel that senses cold stimuli and menthol

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12 December 2020

gon-2, a gene required for gonadogenesis in Caenorhabditis elegans

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12 December 2020

Involvement of transient receptor potential-like channels in responses to mGluR-I activation in midbrain dopamine neurons.

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12 December 2020

Anandamide and arachidonic acid use epoxyeicosatrienoic acids to activate TRPV4 channels

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12 December 2020

Impairment of store-operated Ca2+ entry in TRPC4(-/-) mice interferes with increase in lung microvascular permeability

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12 December 2020

Impaired nociception and pain sensation in mice lacking the capsaicin receptor

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12 December 2020

Social feeding in Caenorhabditis elegans is induced by neurons that detect aversive stimuli

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12 December 2020

Melastatin expression and prognosis in cutaneous malignant melanoma

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12 December 2020

Genetic dissection of mechanosensory transduction: mechanoreception-defective mutations of Drosophila

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12 December 2020

The ankyrin repeat: a diversity of interactions on a common structural framework

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12 December 2020

Transient receptor potential-like channels mediate metabotropic glutamate receptor EPSCs in rat dopamine neurones

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12 December 2020

Renal Ca2+ wasting, hyperabsorption, and reduced bone thickness in mice lacking TRPV5

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12 December 2020

Combinatorial expression of TRPV channel proteins defines their sensory functions and subcellular localization in C. elegans neurons.

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12 December 2020

TRPgamma, a drosophila TRP-related subunit, forms a regulated cation channel with TRPL.

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12 December 2020

Vanilloid receptor-related osmotically activated channel (VR-OAC), a candidate vertebrate osmoreceptor

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12 December 2020

Mutation of TRPM6 causes familial hypomagnesemia with secondary hypocalcemia

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12 December 2020

Molecular approaches to aggregation behavior and social attachment

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12 December 2020

The Promotion of Gonadal Cell Divisions by the Caenorhabditis elegans TRPM Cation Channel GON-2 Is Antagonized by GEM-4 Copine

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12 December 2020

Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways

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12 December 2020

Permeation and gating properties of the novel epithelial Ca(2+) channel

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12 December 2020

Autosomal dominant polycystic kidney disease

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12 December 2020

Heat-evoked activation of TRPV4 channels in a HEK293 cell expression system and in native mouse aorta endothelial cells

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12 December 2020

(Patho)physiological implications of the novel epithelial Ca2+ channels TRPV5 and TRPV6.

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12 December 2020

PKD2 cation channel is required for directional sperm movement and male fertility

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12 December 2020

ECaC: the gatekeeper of transepithelial Ca2+ transport

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12 December 2020

Coordination of an array of signaling proteins through homo- and heteromeric interactions between PDZ domains and target proteins

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12 December 2020

Caenorhabditis elegans functional orthologue of human protein h-mucolipin-1 is required for lysosome biogenesis

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12 December 2020

From worm to man: three subfamilies of TRP channels

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12 December 2020

Congenital corneal clouding with abnormal systemic storage bodies: A new variant of mucolipidosis

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12 December 2020

Polycystin channels and kidney disease.

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12 December 2020

A Drosophila mechanosensory transduction channel

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12 December 2020

A TRPV family ion channel required for hearing in Drosophila

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12 December 2020

Identification of a Drosophila gene encoding a calmodulin-binding protein with homology to the trp phototransduction gene

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12 December 2020

Activation of the TRPC1 cation channel by metabotropic glutamate receptor mGluR1

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12 December 2020

TRPC1 and TRPC5 form a novel cation channel in mammalian brain.

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12 December 2020

Lack of an endothelial store-operated Ca2+ current impairs agonist-dependent vasorelaxation in TRP4-/- mice

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12 December 2020

Physiology, phylogeny, and functions of the TRP superfamily of cation channels

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12 December 2020

The vasculopathy of autosomal dominant polycystic kidney disease: insights from animal models

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12 December 2020

Mammalian TRPV4 (VR-OAC) directs behavioral responses to osmotic and mechanical stimuli in Caenorhabditis elegans

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12 December 2020

N-copine: a novel two C2-domain-containing protein with neuronal activity-regulated expression

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12 December 2020

Homo- and heterotetrameric architecture of the epithelial Ca2+ channels TRPV5 and TRPV6.

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12 December 2020

Molecular mechanism of active Ca2+ reabsorption in the distal nephron

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12 December 2020

Identification and characterization of MTR1, a novel gene with homology to melastatin (MLSN1) and the trp gene family located in the BWS-WT2 critical region on chromosome 11p15.5 and showing allele-specific expression

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12 December 2020

PKD2, a gene for polycystic kidney disease that encodes an integral membrane protein

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12 December 2020

The principle of temperature-dependent gating in cold- and heat-sensitive TRP channels

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12 December 2020

A dual mechanosensory and chemosensory neuron in Caenorhabditis elegans

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12 December 2020

Drosophila Pkd2 is haploid-insufficient for mediating optimal smooth muscle contractility

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12 December 2020

Differential activation of the volume-sensitive cation channel TRP12 (OTRPC4) and volume-regulated anion currents in HEK-293 cells

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12 December 2020

The copines, a novel class of C2 domain-containing, calcium-dependent, phospholipid-binding proteins conserved from Paramecium to humans

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12 December 2020

The Caenorhabditis elegans mucolipin-like gene cup-5 is essential for viability and regulates lysosomes in multiple cell types

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12 December 2020

Down-regulation of the novel gene melastatin correlates with potential for melanoma metastasis

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12 December 2020

Functional analysis of capsaicin receptor (vanilloid receptor subtype 1) multimerization and agonist responsiveness using a dominant negative mutation.

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12 December 2020

Mucolipidosis type IV is caused by mutations in a gene encoding a novel transient receptor potential channel

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12 December 2020

The transient receptor potential protein (Trp), a putative store-operated Ca2+ channel essential for phosphoinositide-mediated photoreception, forms a signaling complex with NorpA, InaC and InaD.

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12 December 2020

Identification of PKD2L, a human PKD2-related gene: tissue-specific expression and mapping to chromosome 10q25

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12 December 2020

Epithelial calcium channels: from identification to function and regulation

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12 December 2020

Polycystin-2 is an intracellular calcium release channel

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12 December 2020

The C. elegans gon-2 gene encodes a putative TRP cation channel protein required for mitotic cell cycle progression

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12 December 2020

TRPM6 forms the Mg2+ influx channel involved in intestinal and renal Mg2+ absorption

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12 December 2020

Translocation of a calcium-permeable cation channel induced by insulin-like growth factor-I

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12 December 2020

Activation of TRPV4 channels (hVRL-2/mTRP12) by phorbol derivatives

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12 December 2020

Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1

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12 December 2020

A unified nomenclature for the superfamily of TRP cation channels.

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12 December 2020

The G alpha protein ODR-3 mediates olfactory and nociceptive function and controls cilium morphogenesis in C. elegans olfactory neurons.

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12 December 2020

A polycystic kidney-disease gene homologue required for male mating behaviour in C. elegans

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12 December 2020

Mucolipidosis type IV.

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12 December 2020

In vivo analysis of the drosophila light-sensitive channels, TRP and TRPL.

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12 December 2020

The role of intraorganellar Ca(2+) in late endosome-lysosome heterotypic fusion and in the reformation of lysosomes from hybrid organelles

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12 December 2020

Identification of PKDL, a novel polycystic kidney disease 2-like gene whose murine homologue is deleted in mice with kidney and retinal defects

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12 December 2020

Mutations in Mcoln3 associated with deafness and pigmentation defects in varitint-waddler (Va) mice

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12 December 2020

A transient receptor potential channel expressed in taste receptor cells

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12 December 2020

A capsaicin-receptor homologue with a high threshold for noxious heat

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12 December 2020

The capsaicin receptor: a heat-activated ion channel in the pain pathway

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12 December 2020

TRPV3 is a temperature-sensitive vanilloid receptor-like protein.

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12 December 2020

A novel protein encoded by the InaD gene regulates recovery of visual transduction in Drosophila

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12 December 2020

The Caenorhabditis elegans autosomal dominant polycystic kidney disease gene homologs lov-1 and pkd-2 act in the same pathway

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12 December 2020

painless, a Drosophila Gene Essential for Nociception

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12 December 2020

Visual transduction in Drosophila.

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12 December 2020

Towards understanding the polycystins

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12 December 2020

ANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperatures

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12 December 2020

Co-assembly of polycystin-1 and -2 produces unique cation-permeable currents

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12 December 2020

A diacylglycerol-gated cation channel in vomeronasal neuron dendrites is impaired in TRPC2 mutant mice: mechanism of pheromone transduction

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12 December 2020

Regulation of the TRP Ca2+ channel by INAD in Drosophila photoreceptors

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12 December 2020

The Drosophila light-activated conductance is composed of the two channels TRP and TRPL.

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12 December 2020

Termination of phototransduction requires binding of the NINAC myosin III and the PDZ protein INAD.

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12 December 2020

10.1007/S00424-004-1314-1

Identifiers

DOI

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PubMed ID

15480752

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PubMed ID

15480752