Activated Kras alters epidermal homeostasis of mouse skin, resulting in redundant skin and defective hair cycling (Q35910748)

11 August 2017

Activated Kras alters epidermal homeostasis of mouse skin, resulting in redundant skin and defective hair cycling (English)

1 reference

11 August 2017

3

Benjamin D-Y Yu

1 reference

11 August 2017

Anandaroop Mukhopadhyay

series ordinal

1

1 reference

PMCID

3335744

11 August 2017

Suguna R Krishnaswami

series ordinal

2

1 reference

PMCID

3335744

11 August 2017

language of work or name

English

0 references

publication date

14 October 2010

1 reference

Journal of Investigative Dermatology

11 August 2017

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11 August 2017

131

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11 August 2017

2

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11 August 2017

311-319

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https://scigraph.springernature.com/pub.10.1038/jid.2010.296

11 August 2017

0 references

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A mouse model for Costello syndrome reveals an Ang II-mediated hypertensive condition

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Cyclic dermal BMP signalling regulates stem cell activation during hair regeneration

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Germline loss-of-function mutations in SPRED1 cause a neurofibromatosis 1-like phenotype

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Hyperactive Ras in developmental disorders and cancer

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Sprouty-2 regulates oncogenic K-ras in lung development and tumorigenesis

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Germline KRAS mutations cause Noonan syndrome

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Germline KRAS and BRAF mutations in cardio-facio-cutaneous syndrome

27 July 2018

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Germline mutations in HRAS proto-oncogene cause Costello syndrome

27 July 2018

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Hair follicle stem cells in the lower bulge form the secondary germ, a biochemically distinct but functionally equivalent progenitor cell population, at the termination of catagen.

27 July 2018

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Conditional expression of K-ras in an epithelial compartment that includes the stem cells is sufficient to promote squamous cell carcinogenesis.

27 July 2018

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gamma-secretase functions through Notch signaling to maintain skin appendages but is not required for their patterning or initial morphogenesis

27 July 2018

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Cutaneous manifestations in the cardiofaciocutaneous syndrome, a variant of the classical Noonan syndrome. Report of a case and review of the literature

27 July 2018

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27 July 2018

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Defining the epithelial stem cell niche in skin

27 July 2018

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Molecular biology of hair morphogenesis: development and cycling

27 July 2018

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Enrichment for living murine keratinocytes from the hair follicle bulge with the cell surface marker CD34.

27 July 2018

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Costello syndrome: an overview

27 July 2018

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Conditional inactivation of Fgf4 reveals complexity of signalling during limb bud development

27 July 2018

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The biology of hair follicles

27 July 2018

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The developmental basis for allometry in insects

27 July 2018

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Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling

27 July 2018

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Cre-mediated somatic site-specific recombination in mice

27 July 2018

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Targeting expression of keratinocyte growth factor to keratinocytes elicits striking changes in epithelial differentiation in transgenic mice

27 July 2018

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A two-step mechanism for stem cell activation during hair regeneration

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335744

Mutation and phenotypic spectrum in patients with cardio-facio-cutaneous and Costello syndrome.

24 September 2018

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A negative feedback signaling network underlies oncogene-induced senescence

24 September 2018

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Germline gain-of-function mutations in SOS1 cause Noonan syndrome

24 September 2018

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Gain-of-function SOS1 mutations cause a distinctive form of Noonan syndrome.

24 September 2018

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Expansion of the genotypic and phenotypic spectrum in patients with KRAS germline mutations

24 September 2018

1 reference

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The GAP1 family of GTPase-activating proteins: spatial and temporal regulators of small GTPase signalling

24 September 2018

1 reference

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The cardiofaciocutaneous syndrome

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335744

Epidermal stem cells of the skin

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335744

Loss of Aif function causes cell death in the mouse embryo, but the temporal progression of patterning is normal

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335744

Germline mutations in genes within the MAPK pathway cause cardio-facio-cutaneous syndrome

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335744

Endogenous oncogenic K-ras(G12D) stimulates proliferation and widespread neoplastic and developmental defects.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335744

Fibulin-5/DANCE is essential for elastogenesis in vivo

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335744

A comprehensive guide for the accurate classification of murine hair follicles in distinct hair cycle stages

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335744

Cholesterol modification of sonic hedgehog is required for long-range signaling activity and effective modulation of signaling by Ptc1

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335744

Feedback control of intercellular signalling in development

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335744

Constitutive expression of erbB2 in epidermis of transgenic mice results in epidermal hyperproliferation and spontaneous skin tumor development

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335744

The Ras branch of small GTPases: Ras family members don't fall far from the tree

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335744

Elastic fiber degeneration in Costello syndrome.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335744

SIGNAL TRANSDUCTION: Prelude to an Anniversary for the RAS Oncogene

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335744

Ras isoforms vary in their ability to activate Raf-1 and phosphoinositide 3-kinase

6 December 2018

1 reference

12 December 2020

Molecular aspects, clinical aspects and possible treatment modalities for Costello syndrome: Proceedings from the 1st International Costello Syndrome Research Symposium 2007

1 reference

12 December 2020

Lgr6 Marks Stem Cells in the Hair Follicle That Generate All Cell Lineages of the Skin

1 reference

12 December 2020

Contrasting expression patterns of CCAAT/enhancer-binding protein transcription factors in the hair follicle and at different stages of the hair growth cycle

1 reference

12 December 2020

Keratinocyte-specific Pten deficiency results in epidermal hyperplasia, accelerated hair follicle morphogenesis and tumor formation

1 reference

12 December 2020

Identifiers

DOI

10.1038/JID.2010.296

1 reference

11 August 2017

1 reference

11 August 2017

1 reference

PMCID

3335744