Colony-stimulating factor 1 receptor inhibition prevents microglial plaque association and improves cognition in 3xTg-AD mice (Q35908248)

11 August 2017

Colony-stimulating factor 1 receptor inhibition prevents microglial plaque association and improves cognition in 3xTg-AD mice (English)

1 reference

11 August 2017

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1

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15 June 2020

Rodrigo Medeiros

6

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15 June 2020

Brian West

7

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15 June 2020

author name string

Allison R Najafi

2

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15 June 2020

Kara M Neely Kayala

3

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15 June 2020

Monica R P Elmore

4

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15 June 2020

Terra E White

5

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15 June 2020

Kim N Green

8

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15 June 2020

language of work or name

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1 August 2015

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Journal of Neuroinflammation

11 August 2017

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15 June 2020

volume

12

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15 June 2020

page(s)

139

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https://scigraph.springernature.com/pub.10.1186/s12974-015-0366-9

15 June 2020

exact match

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cites work

TREM2 lipid sensing sustains the microglial response in an Alzheimer's disease model

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Microglia dictate the impact of saturated fat consumption on hypothalamic inflammation and neuronal function.

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Altered microglial response to Aβ plaques in APPPS1-21 mice heterozygous for TREM2.

27 July 2018

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Colony-stimulating factor 1 receptor signaling is necessary for microglia viability, unmasking a microglia progenitor cell in the adult brain.

27 July 2018

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Increased KIT inhibition enhances therapeutic efficacy in gastrointestinal stromal tumor

27 July 2018

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Deficient neuron-microglia signaling results in impaired functional brain connectivity and social behavior.

27 July 2018

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KIT oncogene inhibition drives intratumoral macrophage M2 polarization.

27 July 2018

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Regulation of microglial proliferation during chronic neurodegeneration

27 July 2018

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Microglia: new roles for the synaptic stripper.

27 July 2018

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Microglial stimulation of glioblastoma invasion involves epidermal growth factor receptor (EGFR) and colony stimulating factor 1 receptor (CSF-1R) signaling

27 July 2018

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The novel object recognition memory: neurobiology, test procedure, and its modifications

27 July 2018

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Absence of colony stimulation factor-1 receptor results in loss of microglia, disrupted brain development and olfactory deficits

27 July 2018

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Fate mapping analysis reveals that adult microglia derive from primitive macrophages

27 July 2018

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Microglial Cx3cr1 knockout prevents neuron loss in a mouse model of Alzheimer's disease

27 July 2018

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Formation and maintenance of Alzheimer's disease beta-amyloid plaques in the absence of microglia

27 July 2018

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Nicotinamide restores cognition in Alzheimer's disease transgenic mice via a mechanism involving sirtuin inhibition and selective reduction of Thr231-phosphotau

27 July 2018

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Discovery of a cytokine and its receptor by functional screening of the extracellular proteome

27 July 2018

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The inflammatory response in stroke

27 July 2018

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Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction

27 July 2018

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Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

27 July 2018

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The duality of the inflammatory response to traumatic brain injury

27 July 2018

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Involvement of Iba1 in membrane ruffling and phagocytosis of macrophages/microglia

27 July 2018

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Developments of a water-maze procedure for studying spatial learning in the rat

27 July 2018

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Elimination of Microglia Improves Functional Outcomes Following Extensive Neuronal Loss in the Hippocampus.

27 July 2018

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TREM2 deficiency eliminates TREM2+ inflammatory macrophages and ameliorates pathology in Alzheimer's disease mouse models.

24 September 2018

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TREM2 and β-catenin regulate bone homeostasis by controlling the rate of osteoclastogenesis

24 September 2018

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Inflammation after trauma: microglial activation and traumatic brain injury.

24 September 2018

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Presenilin is necessary for efficient proteolysis through the autophagy-lysosome system in a γ-secretase-independent manner

24 September 2018

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Reductions in amyloid-beta-derived neuroinflammation, with minocycline, restore cognition but do not significantly affect tau hyperphosphorylation

24 September 2018

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Microglia, amyloid, and cognition in Alzheimer's disease: An [11C](R)PK11195-PET and [11C]PIB-PET study

24 September 2018

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Conditional deletion of the colony stimulating factor-1 receptor (c-fms proto-oncogene) in mice.

24 September 2018

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Intraneuronal Abeta causes the onset of early Alzheimer's disease-related cognitive deficits in transgenic mice

24 September 2018

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Abeta immunotherapy leads to clearance of early, but not late, hyperphosphorylated tau aggregates via the proteasome

24 September 2018

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TGF-beta1 promotes microglial amyloid-beta clearance and reduces plaque burden in transgenic mice.

24 September 2018

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Murine tumor necrosis factor alpha is transported from blood to brain in the mouse.

24 September 2018

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10.1186/S12974-015-0366-9

24 September 2018

Identifiers

DOI

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15 June 2020

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15 June 2020

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