Recombinant IgG2a Fc (M045) multimers effectively suppress experimental autoimmune myasthenia gravis. (Q35899107)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24388113%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

title

Recombinant IgG2a Fc (M045) multimers effectively suppress experimental autoimmune myasthenia gravis (English)

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4 March 2020

0 references

Muthusamy Thiruppathi

1

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4 March 2020

author name string

Jian Rong Sheng

2

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4 March 2020

Liangcheng Li

3

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4 March 2020

Bellur S Prabhakar

4

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4 March 2020

Matthew N Meriggioli

5

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4 March 2020

publication date

2 January 2014

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4 March 2020

published in

Journal of Autoimmunity

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4 March 2020

volume

52

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4 March 2020

page(s)

64-73

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Ectopic germinal centers, BAFF and anti-B-cell therapy in myasthenia gravis

4 March 2020

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Modulation of dendritic cells using granulocyte-macrophage colony-stimulating factor (GM-CSF) delays type 1 diabetes by enhancing CD4+CD25+ regulatory T cell function

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11 July 2018

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11 July 2018

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Fcgamma receptors as regulators of immune responses

11 July 2018

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FcRn: the neonatal Fc receptor comes of age.

11 July 2018

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Tolerogenic dendritic cells and regulatory T cells: a two-way relationship

11 July 2018

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Intravenous immunoglobulin: an update on the clinical use and mechanisms of action.

11 July 2018

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The antiinflammatory activity of IgG: the intravenous IgG paradox

11 July 2018

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Divergent activities of an engineered antibody in murine and human systems have implications for therapeutic antibodies

11 July 2018

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Myasthenia gravis: past, present, and future

11 July 2018

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11 July 2018

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11 July 2018

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High dose intravenous immunoglobulin treatment: mechanisms of action

11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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Therapeutic efficacy of intravenous immunoglobulin preparations depends on the immunoglobulin G dimers: studies in experimental immune thrombocytopenia

11 July 2018

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11 July 2018

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Oral administration of an immunodominant T-cell epitope downregulates Th1/Th2 cytokines and prevents experimental myasthenia gravis

11 July 2018

1 reference

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Fcgamma receptor-mediated induction of dendritic cell maturation and major histocompatibility complex class I-restricted antigen presentation after immune complex internalization

11 July 2018

1 reference

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Interferon gamma (IFN-gamma) is necessary for the genesis of acetylcholine receptor-induced clinical experimental autoimmune myasthenia gravis in mice

11 July 2018

1 reference

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11 July 2018

IgG effector mechanisms.

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Manipulation of the Th1/Th2 balance in autoimmune disease

11 July 2018

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Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation

11 July 2018

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Selective increases in antibody isotypes and immunoglobulin G subclass responses to secreted antigens in tuberculosis patients and healthy household contacts of the patients.

11 July 2018

1 reference

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Are aggregates of IgG the effective part of high-dose immunoglobulin therapy in adult idiopathic thrombocytopenic purpura (ITP)?

11 July 2018

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TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties

11 July 2018

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High doses of intravenous Ig inhibit in vitro uptake of C4 fragments onto sensitized erythrocytes.

11 July 2018

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Beneficial effect of a multimerized immunoglobulin Fc in an animal model of inflammatory neuropathy (experimental autoimmune neuritis).

11 July 2018

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24 September 2018

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IV immunoglobulin in patients with myasthenia gravis: a randomized controlled trial

24 September 2018

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24 September 2018

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Cathepsin S is required for murine autoimmune myasthenia gravis pathogenesis

24 September 2018

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24 September 2018

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CD40, but not CD154, expression on B cells is necessary for optimal primary B cell responses

24 September 2018

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24 September 2018

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24 September 2018

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A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell.

24 September 2018

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TACI attenuates antibody production costimulated by BAFF-R and CD40

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12 December 2020

Discovery and development of biopharmaceuticals: current issues

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29 Production and assay of antibodies to acetylcholine receptors

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Experimental myasthenia gravis in congenic mice. Sequence mapping and H-2 restriction of T helper epitopes on the alpha subunits of Torpedo californica and murine acetylcholine receptors

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T cell costimulatory pathways: promising novel targets for immunosuppression and tolerance induction

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High doses of immunoglobulin G attenuate immune aggregate-mediated complement activation by enhancing physiologic cleavage of C3b in C3bn-IgG complexes

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Cytokines and the pathogenesis of myasthenia gravis

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Mechanisms of nasal tolerance induction in experimental autoimmune myasthenia gravis: identification of regulatory cells

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Intravenous immunoglobulin suppresses experimental myasthenia gravis: immunological mechanisms

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Suppression of experimental autoimmune myasthenia gravis by granulocyte-macrophage colony-stimulating factor is associated with an expansion of FoxP3+ regulatory T cells

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Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24388113%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24388113%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24388113%20AND%20SRC:MED&resulttype=core&format=json