ApoE promotes hepatic selective uptake but not RCT due to increased ABCA1-mediated cholesterol efflux to plasma. (Q35897048)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22383685%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

title

ApoE promotes hepatic selective uptake but not RCT due to increased ABCA1-mediated cholesterol efflux to plasma (English)

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24 January 2020

4

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24 January 2020

Patrick Rensen

5

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24 January 2020

author name string

Wijtske Annema

1

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24 January 2020

Arne Dikkers

2

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24 January 2020

Jan Freark de Boer

3

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24 January 2020

Daniel J Rader

6

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24 January 2020

Uwe J F Tietge

7

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24 January 2020

publication date

1 March 2012

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Journal of Lipid Research

24 January 2020

published in

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24 January 2020

volume

53

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24 January 2020

issue

5

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24 January 2020

page(s)

929-940

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Pharmacologic suppression of hepatic ATP-binding cassette transporter 1 activity in mice reduces high-density lipoprotein cholesterol levels but promotes reverse cholesterol transport

24 January 2020

cites work

1 reference

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Suppressed monocyte recruitment drives macrophage removal from atherosclerotic plaques of Apoe-/- mice during disease regression

11 July 2018

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Apolipoprotein E induces antiinflammatory phenotype in macrophages

11 July 2018

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Myeloperoxidase and serum amyloid A contribute to impaired in vivo reverse cholesterol transport during the acute phase response but not group IIA secretory phospholipase A(2)

11 July 2018

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Hepatic SR-BI, not endothelial lipase, expression determines biliary cholesterol secretion in mice

11 July 2018

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Scavenger receptor BI-mediated selective uptake is required for the remodeling of high density lipoprotein by endothelial lipase

11 July 2018

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Macrophage reverse cholesterol transport: key to the regression of atherosclerosis?

11 July 2018

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Hepatic expression of scavenger receptor class B type I (SR-BI) is a positive regulator of macrophage reverse cholesterol transport in vivo

11 July 2018

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New insights into the regulation of HDL metabolism and reverse cholesterol transport

11 July 2018

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Antimitogenic effects of HDL and APOE mediated by Cox-2-dependent IP activation

11 July 2018

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Reduction of isoprostanes and regression of advanced atherosclerosis by apolipoprotein E.

11 July 2018

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Decreased selective uptake of high density lipoprotein cholesteryl esters in apolipoprotein E knock-out mice

11 July 2018

1 reference

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Apolipoprotein E-dependent cholesterol efflux from macrophages: kinetic study and divergent mechanisms for endogenous versus exogenous apolipoprotein E.

11 July 2018

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Apolipoprotein E inhibits platelet aggregation through the L-arginine:nitric oxide pathway. Implications for vascular disease

11 July 2018

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Apolipoprotein E allele-specific antioxidant activity and effects on cytotoxicity by oxidative insults and beta-amyloid peptides

11 July 2018

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Expression of heterologous human apolipoprotein E by J774 macrophages enhances cholesterol efflux to HDL3.

11 July 2018

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Apolipoprotein E deficiency in mice: gene replacement and prevention of atherosclerosis using adenovirus vectors

11 July 2018

1 reference

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Macrophage-specific expression of human apolipoprotein E reduces atherosclerosis in hypercholesterolemic apolipoprotein E-null mice

11 July 2018

1 reference

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Independent pathways for secretion of cholesterol and apolipoprotein E by macrophages

11 July 2018

1 reference

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Familial apolipoprotein E deficiency

11 July 2018

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Apolipoprotein E: cholesterol transport protein with expanding role in cell biology

11 July 2018

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Quantitation of apolipoprotein E mRNA in the liver and peripheral tissues of nonhuman primates.

11 July 2018

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Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells

11 July 2018

1 reference

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Scavenger receptor class B type I mediates biliary cholesterol secretion independent of ATP-binding cassette transporter g5/g8 in mice.

11 July 2018

1 reference

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Secretory phospholipase A2 increases SR-BI-mediated selective uptake from HDL but not biliary cholesterol secretion

24 September 2018

1 reference

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Effect of macrophage ApoE on atherosclerosis in LDL-receptor deficient mice.

24 September 2018

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Complete prevention of atherosclerosis in apoE-deficient mice by hepatic human apoE gene transfer with adeno-associated virus serotypes 7 and 8.

24 September 2018

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Apolipoprotein E suppresses the type I inflammatory response in vivo

24 September 2018

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Macrophage-specific expression of group IIA sPLA2 results in accelerated atherogenesis by increasing oxidative stress

24 September 2018

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Scavenger receptor class B type I is solely responsible for the selective uptake of cholesteryl esters from HDL by the liver and the adrenals in mice

24 September 2018

1 reference

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A tetracycline-regulated adenoviral expression system for in vivo delivery of transgenes to lung and liver

24 September 2018

1 reference

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Acute inflammation increases selective uptake of HDL cholesteryl esters into adrenals of mice overexpressing human sPLA2.

24 September 2018

1 reference

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Effects of coexpression of the LDL receptor and apoE on cholesterol metabolism and atherosclerosis in LDL receptor-deficient mice

24 September 2018

1 reference

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Apolipoprotein E protects against bacterial lipopolysaccharide-induced lethality. A new therapeutic approach to treat gram-negative sepsis.

24 September 2018

1 reference

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Hepatic expression of apolipoprotein E inhibits progression of atherosclerosis without reducing cholesterol levels in LDL receptor-deficient mice

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329392

Retroviral gene therapy in ApoE-deficient mice: ApoE expression in the artery wall reduces early foam cell lesion formation

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329392

Phospholipid and cholesteryl ester transfer activities in plasma from 14 vertebrate species. Relation to atherogenesis susceptibility.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329392

Uptake of high density lipoprotein cholesterol ester by HepG2 cells involves apolipoprotein E localized on the cell surface.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329392

Apolipoprotein E inhibition of proliferation of mitogen-activated T lymphocytes: production of interleukin 2 with reduced biological activity.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329392

Biliary sterol secretion is required for functional in vivo reverse cholesterol transport in mice

24 September 2018

1 reference

12 December 2020

Macrophage, But Not Systemic, Apolipoprotein E Is Necessary for Macrophage Reverse Cholesterol Transport In Vivo

1 reference

12 December 2020

Increased LCAT activity and hyperglycaemia decrease the antioxidative functionality of HDL

1 reference

12 December 2020

Overexpression of secretory phospholipase A(2) causes rapid catabolism and altered tissue uptake of high density lipoprotein cholesteryl ester and apolipoprotein A-I

1 reference

12 December 2020

Endogenous apolipoprotein E modulates cholesterol efflux and cholesteryl ester hydrolysis mediated by high-density lipoprotein-3 and lipid-free apolipoproteins in mouse peritoneal macrophages

1 reference

12 December 2020

Hepatic apolipoprotein E expression promotes very low density lipoprotein-apolipoprotein B production in vivo in mice

1 reference

12 December 2020

Prevention of atherosclerosis in apolipoprotein E-deficient mice by bone marrow transplantation

1 reference

12 December 2020

Vitamin E suppresses isoprostane generation in vivo and reduces atherosclerosis in ApoE-deficient mice

1 reference

12 December 2020

Rapid regression of atherosclerosis induced by liver-directed gene transfer of ApoE in ApoE-deficient mice

1 reference

12 December 2020

Identifiers

DOI

10.1194/JLR.M020743

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22383685%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22383685%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22383685%20AND%20SRC:MED&resulttype=core&format=json