Regulation of REDD1 by insulin-like growth factor-I in skeletal muscle and myotubes (Q35880350)

10 August 2017

Regulation of REDD1 by insulin-like growth factor-I in skeletal muscle and myotubes (English)

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10 August 2017

Robert A Frost

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10 August 2017

Danuta Huber

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10 August 2017

Anne Pruznak

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10 August 2017

Charles H Lang

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10 August 2017

language of work or name

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1 December 2009

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Journal of Cellular Biochemistry

10 August 2017

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10 August 2017

108

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10 August 2017

5

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10 August 2017

1192-1202

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describes a project that uses

10 August 2017

ImageQuant

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3323118/fullTextXML

inferred from PubMed Central ID database lookup

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REDD2 is enriched in skeletal muscle and inhibits mTOR signaling in response to leucine and stretch

11 July 2018

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11 July 2018

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The TSC-mTOR pathway mediates translational activation of TOP mRNAs by insulin largely in a raptor- or rictor-independent manner

11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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Rapid turnover of the mTOR complex 1 (mTORC1) repressor REDD1 and activation of mTORC1 signaling following inhibition of protein synthesis

11 July 2018

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Nutrient signaling components controlling protein synthesis in striated muscle

11 July 2018

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PRAS40 regulates mTORC1 kinase activity by functioning as a direct inhibitor of substrate binding

11 July 2018

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11 July 2018

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11 July 2018

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Insulin signalling to mTOR mediated by the Akt/PKB substrate PRAS40

11 July 2018

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Dexamethasone represses signaling through the mammalian target of rapamycin in muscle cells by enhancing expression of REDD1.

11 July 2018

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Muscle atrophy in transgenic mice expressing a human TSC1 transgene

11 July 2018

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Activity of TSC2 is inhibited by AKT-mediated phosphorylation and membrane partitioning

11 July 2018

1 reference

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mTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events

11 July 2018

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Multiple Toll-like receptor ligands induce an IL-6 transcriptional response in skeletal myocytes

11 July 2018

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Sarcopenia is more than a muscular deficit

11 July 2018

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Skeletal muscle hypertrophy and atrophy signaling pathways

11 July 2018

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Regulation of mTOR and cell growth in response to energy stress by REDD1.

11 July 2018

1 reference

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Induction of a cell stress response gene RTP801 by DNA damaging agent methyl methanesulfate through CCAA/enhancer binding protein

11 July 2018

1 reference

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Redox paradox: insulin action is facilitated by insulin-stimulated reactive oxygen species with multiple potential signaling targets

11 July 2018

1 reference

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The stress-inducted proteins RTP801 and RTP801L are negative regulators of the mammalian target of rapamycin pathway

11 July 2018

1 reference

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Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex

11 July 2018

1 reference

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Signaling pathways weigh in on decisions to make or break skeletal muscle

11 July 2018

1 reference

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REDD1, a developmentally regulated transcriptional target of p63 and p53, links p63 to regulation of reactive oxygen species

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3323118

Akt regulates growth by directly phosphorylating Tsc2

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3323118

Regulation of elongation factor 2 kinase by p90(RSK1) and p70 S6 kinase.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3323118

Dexamethasone inhibits insulin-like growth factor signaling and potentiates myoblast apoptosis

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3323118

Opposing early inhibitory and late stimulatory effects of insulin-like growth factor-I on myogenin gene transcription

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3323118

Among translational effectors, p70S6k is uniquely sensitive to inhibition by glucocorticoids

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3323118

GeneFisher--software support for the detection of postulated genes.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3323118

SP600125 negatively regulates the mammalian target of rapamycin via ATF4-induced Redd1 expression

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3323118

Hypoxic condition- and high cell density-induced expression of Redd1 is regulated by activation of hypoxia-inducible factor-1alpha and Sp1 through the phosphatidylinositol 3-kinase/Akt signaling pathway.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3323118

IGF-I does not prevent myotube atrophy caused by proinflammatory cytokines despite activation of Akt/Foxo and GSK-3beta pathways and inhibition of atrogin-1 mRNA.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3323118

Growth hormone administration to long-living dwarf mice alters multiple components of the antioxidative defense system

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3323118

Increased protein synthesis after acute IGF-I or insulin infusion is localized to muscle in mice

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3323118

Burn-induced increase in atrogin-1 and MuRF-1 in skeletal muscle is glucocorticoid independent but downregulated by IGF-I

24 September 2018

1 reference

12 December 2020

Role of the transcription factor ATF4 in the anabolic actions of insulin and the anti-anabolic actions of glucocorticoids

1 reference

12 December 2020

Glucocorticoid effects on insulin- and IGF-I-regulated muscle protein metabolism during aging

1 reference

12 December 2020

Overexpression of IGF-I in skeletal muscle of transgenic mice does not prevent unloading-induced atrophy

1 reference

12 December 2020

Insulin-like growth factor-I gene transfer by electroporation prevents skeletal muscle atrophy in glucocorticoid-treated rats

1 reference

12 December 2020

Identifiers

DOI

10.1002/JCB.22349

1 reference

10 August 2017

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10 August 2017

PubMed publication ID

19795384

1 reference