The biology and diagnostic applications of fetal DNA and RNA in maternal plasma (Q35879299)

10 August 2017

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title

The biology and diagnostic applications of fetal DNA and RNA in maternal plasma (English)

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10 August 2017

Rossa W K Chiu

1

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PubMed ID

15350398

10 August 2017

Y M Dennis Lo

series ordinal

2

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10 August 2017

1 January 2004

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Current Topics in Developmental Biology

10 August 2017

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10 August 2017

61

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10 August 2017

81-111

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Fetal cell-free plasma DNA concentrations in maternal blood are stable 24 hours after collection: analysis of first- and third-trimester samples

10 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Kinetics of fetal cellular and cell-free DNA in the maternal circulation during and after pregnancy: implications for noninvasive prenatal diagnosis

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Fetal sex determination from maternal blood at 6 weeks of gestation when at risk for 21-hydroxylase deficiency

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Detection of maternal deoxyribonucleic acid in umbilical cord plasma by using fluorescent polymerase chain reaction amplification of short tandem repeat sequences

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Are fetal cells in maternal plasma really there? We think they are

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Fetal DNA in maternal serum: does it persist after pregnancy?

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Fetal cells in the maternal circulation: feasibility for prenatal diagnosis

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https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Fetomaternal cell trafficking: a new cause of disease?

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https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Isolation of fetal DNA from nucleated erythrocytes in maternal blood

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Fetal gender and aneuploidy detection using fetal cells in maternal blood: analysis of NIFTY I data. National Institute of Child Health and Development Fetal Cell Isolation Study.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

PCR quantitation of fetal cells in maternal blood in normal and aneuploid pregnancies

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Male fetal progenitor cells persist in maternal blood for as long as 27 years postpartum

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Intact fetal cells in maternal plasma: are they really there?

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Cell-free fetal DNA and intact fetal cells in maternal blood circulation: implications for first and second trimester non-invasive prenatal diagnosis

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Fetal DNA quantitation in peripheral blood is not useful as a marker of disease severity in women with preeclampsia.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Cell-free fetal DNA concentration in plasma of patients with abnormal uterine artery Doppler waveform and intrauterine growth restriction--a pilot study

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https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Size distributions of maternal and fetal DNA in maternal plasma.

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https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Serial Analysis of Fetal DNA Concentrations in Maternal Plasma in Late Pregnancy

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Fetal DNA in maternal plasma: the prenatal detection of a paternally inherited fetal aneuploidy

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Microsatellite alterations in plasma DNA of small cell lung cancer patients.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Prenatal exclusion of β thalassaemia major by examination of maternal plasma

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Non-invasive prenatal diagnosis: on the horizon?

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

New strategy for prenatal diagnosis of X-linked disorders

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

First-trimester fetal sex determination in maternal serum using real-time PCR

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Fetal RHD genotyping in maternal serum during the first trimester of pregnancy

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Detection of fetal RHD-specific sequences in maternal plasma

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Prediction of fetal D status from maternal plasma: introduction of a new noninvasive fetal RHD genotyping service

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Plasma DNA as a marker of cancerous cell death. Investigations in patients suffering from lung cancer and in nude mice bearing human tumours

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Prenatal detection of fetal hemoglobin E gene from maternal plasma

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Magnetic cell sorting and the transferrin receptor as potential means of prenatal diagnosis from maternal blood

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Prenatal detection of a cystic fibrosis mutation in fetal DNA from maternal plasma

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Huntington disease-unaffected fetus diagnosed from maternal plasma using QF-PCR.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Early Huntington disease prenatal diagnosis by maternal semiquantitative fluorescent-PCR.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Kinetics of SRY gene appearance in maternal serum: detection by real time PCR in early pregnancy after assisted reproductive technique

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Fetal cells and cell-free fetal DNA in maternal blood: new insights into pre-eclampsia

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Prenatal diagnosis using fetal cells and cell-free fetal DNA in maternal blood: what is currently feasible?

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Fetal nucleated cells in maternal peripheral blood after delivery in cases of fetomaternal hemorrhage

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Disturbed feto-maternal cell traffic in preeclampsia.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Fetal gender determination in early pregnancy through qualitative and quantitative analysis of fetal DNA in maternal serum

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Quantitative analysis of DNA levels in maternal plasma in normal and Down syndrome pregnancies

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Replicate real-time PCR testing of DNA in maternal plasma increases the sensitivity of non-invasive fetal sex determination

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https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Presence of fetal DNA in maternal plasma decades after pregnancy

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https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Placenta increta: Postpartum monitoring of plasma cell-free fetal DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Quantitative analysis of male fetal DNA in maternal serum of gravid rhesus monkeys (Macaca mulatta).

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Evidence against the long-term persistence of fetal DNA in maternal plasma after pregnancy

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https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Changes in Concentration of DNA in Serum and Plasma during Storage of Blood Samples

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https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

EDTA is a better anticoagulant than heparin or citrate for delayed blood processing for plasma DNA analysis

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Male microchimerism in healthy women and women with scleroderma: cells or circulating DNA? A quantitative answer

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Cell-free fetal deoxyribonucleic acid in maternal circulation as a marker of fetal-maternal hemorrhage in patients undergoing external cephalic version near term

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Down syndrome and cell-free fetal DNA in archived maternal serum.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Quantitation of genomic DNA in plasma and serum samples: higher concentrations of genomic DNA found in serum than in plasma

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Maternal plasma fetal DNA as a marker for preterm labour.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Inability to detect cell free fetal DNA in the urine of normal pregnant women nor in those affected by preeclampsia associated HELLP syndrome

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https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Presence of fetal DNA in maternal plasma and serum

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Prenatal Diagnosis of Fetal RhD Status by Molecular Analysis of Maternal Plasma

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Prenatal sex determination by DNA amplification from maternal peripheral blood

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

The ins and outs of fetal DNA in maternal plasma

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Quantitative analysis of fetal DNA in maternal plasma and serum: implications for noninvasive prenatal diagnosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Rapid clearance of fetal DNA from maternal plasma

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Screening for Down's Syndrome — Too Many Choices?

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Microsatellite alterations in serum DNA of head and neck cancer patients

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Pregnancy and microchimerism in autoimmune disease: protector or insurgent?

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Genotyping fetal DNA by non-invasive means: extraction from maternal plasma

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https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

The concentration of circulating corticotropin-releasing hormone mRNA in maternal plasma is increased in preeclampsia.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

mRNA of placental origin is readily detectable in maternal plasma.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Quantitation of fetal DNA in maternal serum in normal and aneuploid prenancies

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

The RHD gene is highly detectable in RhD-negative Japanese donors

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Detection of Chromosome 21-encoded mRNA of Placental Origin in Maternal Plasma

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Quantitative fluorescence polymerase chain reaction for the rapid prenatal detection of common aneuploidies and fetal sex.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Detection of male and female fetal DNA in maternal plasma by multiplex fluorescent polymerase chain reaction amplification of short tandem repeats

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Prenatal detection of fetal Down's syndrome from maternal plasma

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Effects of filtration on glyceraldehyde-3-phosphate dehydrogenase mRNA in the plasma of trauma patients and healthy individuals.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Prenatal genotyping of RHD and SRY using maternal blood.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Pre-eclampsia, the placenta and the maternal systemic inflammatory response--a review

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Non-invasive determination of the paternal HLA haplotype of a fetus using kinetic PCR to detect fetal microchimerism in maternal plasma

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Fetal sex determination from maternal plasma in pregnancies at risk for congenital adrenal hyperplasia

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Recent Insights into the pathogenesis of pre-eclampsia

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Histomorphological Features of Chorionic Villi at 10–14 Weeks of Gestation in Trisomic and Chromosomally Normal Pregnancies

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Excretion of deoxyribonucleic acid by lymphocytes stimulated with phytohemagglutinin or antigen

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Prenatal DNA diagnosis of a single-gene disorder from maternal plasma

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Cell-free fetal DNA in maternal circulation after amniocentesis

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Cell-free fetal DNA in the plasma of pregnant women with severe fetal growth restriction

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Apoptosis in fetal nucleated erythrocytes circulating in maternal blood

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Evaluation of bidirectional transfer of plasma DNA through placenta

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Fetal DNA in Maternal Plasma in Twin Pregnancies

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

No evidence of fetal DNA persistence in maternal plasma after pregnancy

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Placental apoptosis in normal human pregnancy

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Increased total cell-free DNA in the serum of pregnant women carrying a fetus affected by trisomy 21.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Invasion of the trophoblasts

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https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Relationship between severity of hyperemesis gravidarum and fetal DNA concentration in maternal plasma.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Effects of blood-processing protocols on cell-free DNA quantification in plasma

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Clinical applications of fetal sex determination in maternal blood in a preimplantation genetic diagnosis centre

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Deoxybonucleic acid (DNA) and antibodies to DNA in the serum of patients with systemic lupus erythematosus

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Integrated screening for Down's syndrome based on tests performed during the first and second trimesters

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

First-trimester screening for trisomies 21 and 18

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Maternal serum cell-free fetal DNA levels are increased in cases of trisomy 13 but not trisomy 18.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Fetal granulocytes in maternal venous blood detected by in situ hybridization

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Fetal DNA in maternal plasma is elevated in pregnancies with aneuploid fetuses

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Fluctuation of maternal and fetal free extracellular circulatory DNA in maternal plasma

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Cell-free fetal DNA in the maternal circulation does not stem from the transplacental passage of fetal erythroblasts.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

High levels of fetal erythroblasts and fetal extracellular DNA in the peripheral blood of a pregnant woman with idiopathic polyhydramnios: case report

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

Elevation of both maternal and fetal extracellular circulating deoxyribonucleic acid concentrations in the plasma of pregnant women with preeclampsia

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2961004-0

7 January 2021

10.1016/S0070-2153(04)61004-0

Identifiers

DOI

1 reference

10 August 2017

1 reference

PubMed ID

15350398