NF-kappaB pathway inhibitors preferentially inhibit breast cancer stem-like cells (Q35872462)

10 August 2017

NF-kappaB pathway inhibitors preferentially inhibit breast cancer stem-like cells (English)

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10 August 2017

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5

Joseph B Margolick

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10 August 2017

Jiangbing Zhou

1

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10 August 2017

Hao Zhang

2

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10 August 2017

Peihua Gu

3

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10 August 2017

Jining Bai

4

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10 August 2017

Ying Zhang

6

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10 August 2017

language of work or name

English

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publication date

27 October 2007

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Breast Cancer Research and Treatment

10 August 2017

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10 August 2017

111

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10 August 2017

419-427

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10 August 2017

3

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https://scigraph.springernature.com/pub.10.1007/s10549-007-9798-y

10 August 2017

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11 July 2018

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11 July 2018

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Cancer stem cells: AMLs show the way.

11 July 2018

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Stem cell research: paths to cancer therapies and regenerative medicine

11 July 2018

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Feverfew: weeding out the root of leukaemia

11 July 2018

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Effects of imatinib and interferon on primitive chronic myeloid leukaemia progenitors

11 July 2018

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Multiple drug resistance in cancer revisited: the cancer stem cell hypothesis

11 July 2018

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Side population is enriched in tumorigenic, stem-like cancer cells, whereas ABCG2+ and ABCG2- cancer cells are similarly tumorigenic

11 July 2018

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Contribution of the ABC transporters Bcrp1 and Mdr1a/1b to the side population phenotype in mammary gland and bone marrow of mice

11 July 2018

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Isolation and in vitro propagation of tumorigenic breast cancer cells with stem/progenitor cell properties

11 July 2018

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The sesquiterpene lactone parthenolide in combination with docetaxel reduces metastasis and improves survival in a xenograft model of breast cancer.

11 July 2018

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Tumour stem cells and drug resistance

11 July 2018

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Cancer stem cell biology: from leukemia to solid tumors

11 July 2018

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Will cancer stem cells provide new therapeutic targets?

11 July 2018

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Therapeutic implications of cancer stem cells.

11 July 2018

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Cancer stem cells: are we missing the target?

11 July 2018

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Considerations for targeting malignant stem cells in leukemia

11 July 2018

1 reference

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Persistence of a small subpopulation of cancer stem-like cells in the C6 glioma cell line

11 July 2018

1 reference

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Enhancement of lipopolysaccharide-stimulated JNK activity in rat aortic smooth muscle cells by pharmacological and adenovirus-mediated inhibition of inhibitory kappa B kinase signalling

11 July 2018

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In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells

11 July 2018

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Prospective identification of tumorigenic breast cancer cells

11 July 2018

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Stem cells, cancer, and cancer stem cells

11 July 2018

1 reference

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The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype

11 July 2018

1 reference

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The anti-inflammatory natural product parthenolide from the medicinal herb Feverfew directly binds to and inhibits IkappaB kinase

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320112

Cysteine 38 in p65/NF-kappaB plays a crucial role in DNA binding inhibition by sesquiterpene lactones

11 July 2018

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Annual report to the nation on the status of cancer (1973 through 1998), featuring cancers with recent increasing trends

11 July 2018

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Development of a sensitive multi-well colorimetric assay for active NFkappaB

11 July 2018

1 reference

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Suppression of NF-kappaB activity by sulfasalazine is mediated by direct inhibition of IkappaB kinases alpha and beta

11 July 2018

1 reference

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The antiinflammatory sesquiterpene lactone parthenolide inhibits NF-kappa B by targeting the I kappa B kinase complex.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320112

Fish oil supplementation enhanced CPT-11 (irinotecan) efficacy against MCF7 breast carcinoma xenografts and ameliorated intestinal side-effects

11 July 2018

1 reference

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Sulindac inhibits activation of the NF-kappaB pathway

11 July 2018

1 reference

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Radiosensitization of human tumor cells by the phosphatidylinositol3-kinase inhibitors wortmannin and LY294002 correlates with inhibition of DNA-dependent protein kinase and prolonged G2-M delay

11 July 2018

1 reference

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Quercetin inhibits hydrogen peroxide (H2O2)-induced NF-kappaB DNA binding activity and DNA damage in HepG2 cells

11 July 2018

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Tamoxifen for early breast cancer: an overview of the randomised trials. Early Breast Cancer Trialists' Collaborative Group

11 July 2018

1 reference

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Protein tyrosine kinase inhibitors block tumor necrosis factor-induced activation of nuclear factor-kappaB, degradation of IkappaBalpha, nuclear translocation of p65, and subsequent gene expression

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320112

Dye efflux studies suggest that hematopoietic stem cells expressing low or undetectable levels of CD34 antigen exist in multiple species.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320112

Cyclosporine A is an uncompetitive inhibitor of proteasome activity and prevents NF-kappaB activation.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320112

Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320112

Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320112

A cell initiating human acute myeloid leukaemia after transplantation into SCID mice

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320112

Dithiocarbamates as potent inhibitors of nuclear factor kappa B activation in intact cells

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320112

Roots and stems: stem cells in cancer.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320112

Inhibition of IKK down-regulates antigen + IgE-induced TNF production by mast cells: a role for the IKK-IkappaB-NF-kappaB pathway in IgE-dependent mast cell activation

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320112

A distinct "side population" of cells in human tumor cells: implications for tumor biology and therapy

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320112

Cell death in human acute myelogenous leukemic cells induced by pyrrolidinedithiocarbamate.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320112

Survival of acute myeloid leukemia cells requires PI3 kinase activation

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320112

Primitive, quiescent, Philadelphia-positive stem cells from patients with chronic myeloid leukemia are insensitive to STI571 in vitro

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320112

Nuclear factor-kappaB is constitutively activated in primitive human acute myelogenous leukemia cells

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320112

The NF-kappaB inhibitor diethyldithiocarbamate (DDTC) increases brain cell death in a transient middle cerebral artery occlusion model of ischemia

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320112

UK and USA breast cancer deaths down 25% in year 2000 at ages 20-69 years.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320112

Proteasome inhibitors activate stress kinases and induce Hsp72. Diverse effects on apoptosis

24 September 2018

1 reference

12 December 2020

Polychemotherapy for early breast cancer: an overview of the randomised trials. Early Breast Cancer Trialists' Collaborative Group

1 reference

12 December 2020

1 reference

12 December 2020

Activation of transcription factor NF-kappa B is suppressed by curcumin (diferuloylmethane) [corrected]

1 reference

12 December 2020

Sesquiterpene lactones specifically inhibit activation of NF-kappa B by preventing the degradation of I kappa B-alpha and I kappa B-beta

1 reference

12 December 2020

Human acute myeloid leukemia CD34+/CD38- progenitor cells have decreased sensitivity to chemotherapy and Fas-induced apoptosis, reduced immunogenicity, and impaired dendritic cell transformation capacities

1 reference

12 December 2020

10.1007/S10549-007-9798-Y

Identifiers

DOI

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10 August 2017

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10 August 2017

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