First-phase insulin secretion: does it exist in real life? Considerations on shape and function (Q35861874)

10 August 2017

1 reference

title

First-phase insulin secretion: does it exist in real life? Considerations on shape and function (English)

1 reference

10 August 2017

Livio Luzi

2

0 references

author name string

Andrea Caumo

series ordinal

1

1 reference

PubMed ID

15308473

10 August 2017

language of work or name

1 reference

1 September 2004

1 reference

American Journal of Physiology - Endocrinology and Metabolism

10 August 2017

1 reference

10 August 2017

287

1 reference

10 August 2017

3

1 reference

10 August 2017

E371-85

1 reference

Peripheral effects of insulin dominate suppression of fasting hepatic glucose production

10 August 2017

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

Autonomic regulation of islet hormone secretion--implications for health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

Effects of a change in the pattern of insulin delivery on carbohydrate tolerance in diabetic and nondiabetic humans in the presence of differing degrees of insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

Mechanisms of the age-associated deterioration in glucose tolerance: contribution of alterations in insulin secretion, action, and clearance

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

Use of a novel triple-tracer approach to assess postprandial glucose metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

Quantitative estimation of insulin sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

Physiologic evaluation of factors controlling glucose tolerance in man: measurement of insulin sensitivity and beta-cell glucose sensitivity from the response to intravenous glucose

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

Altered homeostatic adaptation of first- and second-phase beta-cell secretion in the offspring of patients with type 2 diabetes: studies with a minimal model to assess beta-cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

Oral glucose tolerance test minimal model indexes of beta-cell function and insulin sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

Insulin secretion rate during glucose stimuli: alternative analyses of C-peptide data

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

Gastrointestinal Hormones and the Control of Insulin Secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

Cephalic phase metabolic responses in normal weight adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

Loss of early phase of insulin release in humans impairs glucose tolerance and blunts thermic effect of glucose

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

The effect of rate and dose of glucose infusion on the acute insulin response in man

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

Physiological consequences of phasic insulin release in the normal animal

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

Diminished Insulin Response to Hyperglycemia in Prediabetes and Diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

Assessment of beta-cell function during the oral glucose tolerance test by a minimal model of insulin secretion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

Dynamics of Insulin Secretion by the Perfused Rat Pancreas

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

Identification of the docked granule pool responsible for the first phase of glucose-stimulated insulin secretion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

Lilly lecture 1987. The triumvirate: beta-cell, muscle, liver. A collusion responsible for NIDDM.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

Glucose clamp technique: a method for quantifying insulin secretion and resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

Loss of early insulin secretion leads to postprandial hyperglycaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

The importance of first-phase insulin secretion: implications for the therapy of type 2 diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

Prehepatic insulin production in man: kinetic analysis using peripheral connecting peptide behavior.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

In praise of the hyperglycemic clamp. A method for assessment of beta-cell sensitivity and insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

Escape of hepatic glucose production during hyperglycemic clamp

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

Biphasic insulin secretion during intravenous glucose tolerance test promotes optimal interstitial insulin profile

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

Importance of peripheral insulin levels for insulin-induced suppression of glucose production in depancreatized dogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

A threshold distribution hypothesis for packet storage of insulin and its mathematical modeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

A new phase of insulin secretion. How will it contribute to our understanding of beta-cell function?

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

Evaluation of simple indices of insulin sensitivity and insulin secretion for use in epidemiologic studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

A P387L variant in protein tyrosine phosphatase-1B (PTP-1B) is associated with type 2 diabetes and impaired serine phosphorylation of PTP-1B in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

Repaglinide acutely amplifies pulsatile insulin secretion by augmentation of burst mass with no effect on burst frequency.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

Quantification of the relationship between insulin sensitivity and beta-cell function in human subjects. Evidence for a hyperbolic function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

Reduced amylin release is a characteristic of impaired glucose tolerance and type 2 diabetes in Japanese Americans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

Validation of methods for measurement of insulin secretion in humans in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

Cephalic phase of pancreatic secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

Pulsatility of insulin and glucagon release: physiological significance and pharmacological implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

Hepatic glucose production is regulated both by direct hepatic and extrahepatic effects of insulin in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

Threshold secretory mechanism: a model of derivative element in biological control.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

Evidence that insulin can directly inhibit hepatic glucose production

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

Mathematical modeling in glucose metabolism and insulin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

A model for glucose control of insulin secretion during 24 h of free living

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

Physiological implications of pulsatile hormone secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

Role of reduced suppression of glucose production and diminished early insulin release in impaired glucose tolerance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

Contribution of abnormal muscle and liver glucose metabolism to postprandial hyperglycemia in NIDDM.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

Modeling phasic insulin release: immediate and time-dependent effects of glucose

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

Comparison of storage- and signal-limited models of pancreatic insulin secretion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

Methods for clinical assessment of insulin sensitivity and beta-cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

Effects of pulsatile delivery of insulin and glucagon in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

Plasma Insulin Responses to Oral and Intravenous Glucose: Studies in Normal and Diabetic Subjects*

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

Understanding oral glucose tolerance: comparison of glucose or insulin measurements during the oral glucose tolerance test with specific measurements of insulin resistance and insulin secretion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

Reconstructing insulin secretion rate after a glucose stimulus by an improved stochastic deconvolution method

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

Lilly Lecture 1994. The beta-cell in diabetes: from molecular genetics to clinical research

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

Temporal profiles and clinical significance of pulsatile insulin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

The in vivo regulation of pulsatile insulin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

Pulsatile insulin secretion: detection, regulation, and role in diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

Banting lecture 1990. Beta-cells in type II diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

Insulin responses to glucose: evidence for a two pool system in man

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

Dynamics of glucose production and uptake are more closely related to insulin in hindlimb lymph than in thoracic duct lymph

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

The role of impaired early insulin secretion in the pathogenesis of Type II diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

Causal linkage between insulin suppression of lipolysis and suppression of liver glucose output in dogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

Insulin Secretion in Response to Glycemic Stimulus: Relation of Delayed Initial Release to Carbohydrate intolerance in Mild Diabetes Mellitus*

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

Insulin secretion and clearance. Comparison after oral and intravenous glucose.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

Peripheral insulin parallels changes in insulin secretion more closely than C-peptide after bolus intravenous glucose administration

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

A model of the kinetics of insulin in man.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

Insulin and myocardial blood flow

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

Quantitative estimation of beta cell sensitivity to glucose in the intact organism: a minimal model of insulin kinetics in the dog.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

Quantitative indexes of beta-cell function during graded up&down glucose infusion from C-peptide minimal models

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

Estimation of beta-cell sensitivity from intravenous glucose tolerance test C-peptide data. Knowledge of the kinetics avoids errors in modeling the secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

Glucagon physiology and pathophysiology in the light of new advances

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

Estimation of insulin secretion rates from C-peptide levels. Comparison of individual and standard kinetic parameters for C-peptide clearance

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

Calculated pattern of intraportal insulin appearance without independent assessment of C-peptide kinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

Prehepatic beta-cell secretion during the intravenous glucose tolerance test in humans: application of a combined model of insulin and C-peptide kinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

Insulin transport across capillaries is rate limiting for insulin action in dogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00139.2003

10.1152/AJPENDO.00139.2003

21 January 2018

Identifiers

DOI

1 reference

10 August 2017

1 reference

PubMed ID

15308473