The integration of lipid-sensing and anti-inflammatory effects: how the PPARs play a role in metabolic balance (Q35855689)

10 August 2017

1 reference

title

The integration of lipid-sensing and anti-inflammatory effects: how the PPARs play a role in metabolic balance (English)

1 reference

10 August 2017

Alistair V W Nunn

1

1 reference

10 August 2017

Jimmy Bell

series ordinal

2

1 reference

10 August 2017

Philip Barter

series ordinal

3

1 reference

10 August 2017

25 May 2007

1 reference

10 August 2017

1 reference

10 August 2017

5

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10 August 2017

1

1 reference

10 August 2017

1

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Creative Commons Attribution 2.0 Generic

10 August 2017

start time

25 May 2007

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

1 reference

April 2022 Public Data File from Crossref

exact match

https://scigraph.springernature.com/pub.10.1186/1478-1336-5-1

0 references

cites work

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11 July 2018

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Proline oxidase, a proapoptotic gene, is induced by troglitazone: evidence for both peroxisome proliferator-activated receptor gamma-dependent and -independent mechanisms

11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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Is the Ala12 variant of the PPARG gene an "unthrifty allele"?

11 July 2018

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A forkhead in the road to longevity: the molecular basis of lifespan becomes clearer

11 July 2018

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Prostaglandin D(2) and J(2) induce apoptosis in human leukemia cells via activation of the caspase 3 cascade and production of reactive oxygen species

11 July 2018

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PPAR delta: an uncompletely known nuclear receptor

11 July 2018

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Nuclear factor-kappaB activation leads to down-regulation of fatty acid oxidation during cardiac hypertrophy

11 July 2018

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Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR120

11 July 2018

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15-deoxy-Delta-12,14-prostaglandin J2 induces programmed cell death of breast cancer cells by a pleiotropic mechanism

11 July 2018

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Circulating leptin mediates lipopolysaccharide-induced anorexia and fever in rats

11 July 2018

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Mimetics of caloric restriction include agonists of lipid-activated nuclear receptors

11 July 2018

1 reference

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Role of Peroxisome Proliferator-Activated Receptors in Inflammation Control

11 July 2018

1 reference

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Activating FOXO3a, NF-kappaB and p53 by targeting IKKs: an effective multi-faceted targeting of the tumor-cell phenotype?

11 July 2018

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Adipocyte differentiation induces dynamic changes in NF-kappaB expression and activity

11 July 2018

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Stress- (and diet-) related regulation of hepatic nuclear receptors and its relevance for ABC-transporter functions

11 July 2018

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Is susceptibility to weight gain characterized by homeostatic or hedonic risk factors for overconsumption?

11 July 2018

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Links between fatty acids and expression of UCP2 and UCP3 mRNAs

11 July 2018

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Mitochondrial uncoupling proteins--facts and fantasies.

11 July 2018

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Elevation of free fatty acids induces inflammation and impairs vascular reactivity in healthy subjects

11 July 2018

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Insulin resistance and elevated triglyceride in muscle: more important for survival than ‘thrifty’ genes?

11 July 2018

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Diabetes mellitus: a "thrifty" genotype rendered detrimental by "progress"?

11 July 2018

1 reference

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Convergence of peroxisome proliferator-activated receptor gamma and Foxo1 signaling pathways

11 July 2018

1 reference

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IL-1beta-mediated up-regulation of HIF-1alpha via an NFkappaB/COX-2 pathway identifies HIF-1 as a critical link between inflammation and oncogenesis

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899481

Plant-based foods and prevention of cardiovascular disease: an overview

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899481

Melanocortin signaling and anorexia in chronic disease states

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899481

Thiazolidinediones in type 2 diabetes mellitus: current clinical evidence

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899481

Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899481

A novel role for the hypoxia inducible transcription factor HIF-1alpha: critical regulation of inflammatory cell function.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899481

Peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1 alpha): transcriptional coactivator and metabolic regulator

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899481

A forkhead transcription factor FKHR up-regulates lipoprotein lipase expression in skeletal muscle

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899481

The mitochondrial uncoupling proteins

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899481

Effects of fibrates on serum metabolic parameters.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899481

Angiotensin II as a pro-inflammatory mediator.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899481

PPAR expression and function during vertebrate development

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899481

Polyunsaturated fatty acids stimulate hepatic UCP-2 expression via a PPARalpha-mediated pathway

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899481

Effects of acute changes of plasma free fatty acids on intramyocellular fat content and insulin resistance in healthy subjects

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899481

Chronic activation of the innate immune system may underlie the metabolic syndrome

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899481

Hypoxia-inducible factor 1-mediated inhibition of peroxisome proliferator-activated receptor alpha expression during hypoxia

11 July 2018

1 reference

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Coconut fat and serum lipoproteins: effects of partial replacement with unsaturated fats

11 July 2018

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Circulating interleukin 6 levels, blood pressure, and insulin sensitivity in apparently healthy men and women.

11 July 2018

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Peroxisome proliferator-activated receptors: from genes to physiology

11 July 2018

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Inflammation and cancer: back to Virchow?

11 July 2018

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The ligands/activators for peroxisome proliferator-activated receptor alpha (PPARalpha) and PPARgamma increase Cu2+,Zn2+-superoxide dismutase and decrease p22phox message expressions in primary endothelial cells

11 July 2018

1 reference

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Dietary fatty acids Up-regulate the expression of UCP2 in 3T3-L1 preadipocytes

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899481

Role of redox-regulated transcription factors in inflammation, aging and age-related diseases

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899481

Cellular oxygen sensing by mitochondria: old questions, new insight

11 July 2018

1 reference

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The coactivator PGC-1 cooperates with peroxisome proliferator-activated receptor alpha in transcriptional control of nuclear genes encoding mitochondrial fatty acid oxidation enzymes

11 July 2018

1 reference

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Insulin resistance and inflammation in an evolutionary perspective: the contribution of cytokine genotype/phenotype to thriftiness

11 July 2018

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Effects of the peroxisome proliferator clofibric acid on superoxide dismutase expression in the human HepG2 hepatoma cell line

11 July 2018

1 reference

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A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis

11 July 2018

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Evolution of the nuclear receptor superfamily: early diversification from an ancestral orphan receptor

11 July 2018

1 reference

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NIDDM as a disease of the innate immune system: association of acute-phase reactants and interleukin-6 with metabolic syndrome X.

11 July 2018

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Up-regulation of UCP-2 gene expression by PPAR agonists in preadipose and adipose cells.

11 July 2018

1 reference

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The insulinotropic potency of fatty acids is influenced profoundly by their chain length and degree of saturation

11 July 2018

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Differentiation-dependent expression of the brown adipocyte uncoupling protein gene: regulation by peroxisome proliferator-activated receptor gamma

11 July 2018

1 reference

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Early hormonal changes affect the catabolic response to trauma.

11 July 2018

1 reference

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Alterations in carbohydrate metabolism during stress: a review of the literature

11 July 2018

1 reference

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The kinetics of the autoxidation of polyunsaturated fatty acids.

11 July 2018

1 reference

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Stone agers in the fast lane: chronic degenerative diseases in evolutionary perspective

11 July 2018

1 reference

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The effects of injury and sepsis on fuel utilization

11 July 2018

1 reference

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Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators

11 July 2018

1 reference

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Insulin is a prominent modulator of the cytokine-stimulated expression of acute-phase plasma protein genes

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899481

Variability of appetite control mechanisms in response to 9 weeks of progressive overfeeding in humans.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899481

Reduced skeletal muscle uncoupling protein-3 content in prediabetic subjects and type 2 diabetic patients: restoration by rosiglitazone treatment.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899481

Free fatty acids produce insulin resistance and activate the proinflammatory nuclear factor-kappaB pathway in rat liver.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899481

Hypothalamic phosphatidylinositol 3-kinase-phosphodiesterase 3B-cyclic AMP pathway of leptin signalling is impaired following chronic central leptin infusion.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899481

Effects of acute starvation on insulin resistance in obese patients with and without type 2 diabetes mellitus.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899481

Leptin regulates energetic tradeoffs between body fat and humoural immunity.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899481

Consumption of a fat-rich diet activates a proinflammatory response and induces insulin resistance in the hypothalamus.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899481

Rosiglitazone increases indexes of stearoyl-CoA desaturase activity in humans: link to insulin sensitization and the role of dominant-negative mutation in peroxisome proliferator-activated receptor-gamma

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899481

Regulation of metabolic transcriptional co-activators and transcription factors with acute exercise.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899481

Redistribution of glucose from skeletal muscle to adipose tissue during catch-up fat: a link between catch-up growth and later metabolic syndrome

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899481

Adiponectin inhibits LPS-induced NF-kappaB activation and IL-6 production and increases PPARgamma2 expression in adipocytes

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899481

Modulation of PPAR in aging, inflammation, and calorie restriction.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899481

PPAR-gamma overexpression selectively suppresses insulin secretory capacity in isolated pancreatic islets through induction of UCP-2 protein

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899481

Pancreatic islet adaptation to fasting is dependent on peroxisome proliferator-activated receptor alpha transcriptional up-regulation of fatty acid oxidation

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899481

Circulating adiponectin levels increase in rats on caloric restriction: the potential for insulin sensitization

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899481

Expression of lung uncoupling protein-2 mRNA is modulated developmentally and by caloric intake

24 September 2018

1 reference

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The ketogenic diet increases mitochondrial uncoupling protein levels and activity.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899481

Endurance training in humans leads to fiber type-specific increases in levels of peroxisome proliferator-activated receptor-gamma coactivator-1 and peroxisome proliferator-activated receptor-alpha in skeletal muscle.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899481

The Finnish Diabetes Prevention Study (DPS): Lifestyle intervention and 3-year results on diet and physical activity

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899481

Activating omega-6 polyunsaturated fatty acids and inhibitory purine nucleotides are high affinity ligands for novel mitochondrial uncoupling proteins UCP2 and UCP3.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899481

The interleukin-6 (-174) G/C promoter polymorphism is associated with type-2 diabetes mellitus in Native Americans and Caucasians.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899481

Is the energy homeostasis system inherently biased toward weight gain?

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899481

NF-kappaB plays a key role in hypoxia-inducible factor-1-regulated erythropoietin gene expression

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899481

Angiotensin II is associated with activation of NF-kappaB-mediated genes and downregulation of PPARs.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899481

Role of mitochondrial oxidant generation in endothelial cell responses to hypoxia

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899481

Inhibition of PPAR gamma 2 gene expression by the HIF-1-regulated gene DEC1/Stra13: a mechanism for regulation of adipogenesis by hypoxia

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899481

PPARalpha and PPARdelta activators inhibit cytokine-induced nuclear translocation of NF-kappaB and expression of VCAM-1 in EAhy926 endothelial cells

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899481

Role of peroxisome proliferator-activated receptor-alpha in the mechanism underlying changes in renal pyruvate dehydrogenase kinase isoform 4 protein expression in starvation and after refeeding

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899481

Rat PPARs: quantitative analysis in adult rat tissues and regulation in fasting and refeeding.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899481

Peroxisome proliferator-activated receptor (PPAR)-alpha activation lowers muscle lipids and improves insulin sensitivity in high fat-fed rats: comparison with PPAR-gamma activation

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899481

Serum fatty acids and the risk of coronary heart disease

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899481

Differential regulation of metabolic genes in skeletal muscle during starvation and refeeding in humans

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899481

Peroxisome proliferator-activated receptor delta controls muscle development and oxidative capability

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899481

Improvement of Insulin Sensitivity after Peroxisome Proliferator-Activated Receptor-α Agonist Treatment Is Accompanied by Paradoxical Increase of Circulating Resistin Levels

14 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899481

Constitutive activation of NF-kappa B in an animal model of aging

14 November 2018

1 reference

12 December 2020

Starvation diet and very-low-calorie diets may induce insulin resistance and overt diabetes mellitus

1 reference

12 December 2020

Peroxisome Proliferator-activated Receptor α Negatively Regulates the Vascular Inflammatory Gene Response by Negative Cross-talk with Transcription Factors NF-κB and AP-1

1 reference

12 December 2020

Peroxisome Proliferator-activated Receptor α Activation Modulates Cellular Redox Status, Represses Nuclear Factor-κB Signaling, and Reduces Inflammatory Cytokine Production in Aging

1 reference

12 December 2020

Angiotensin II induces nuclear factor (NF)-kappaB1 isoforms to bind the angiotensinogen gene acute-phase response element: a stimulus-specific pathway for NF-kappaB activation

1 reference

12 December 2020

Starvation-sensitive UCP 3 protein expression in thymus and spleen mitochondria

1 reference

12 December 2020

Peroxisome proliferator-activated receptors gamma and alpha mediate in vivo regulation of uncoupling protein (UCP-1, UCP-2, UCP-3) gene expression.

1 reference

12 December 2020

[The relationship of the lifespan of eukaryotes (animals and plants) to their physical characteristics]

1 reference

12 December 2020

Induction of the rat Cu/Zn superoxide dismutase gene through the peroxisome proliferator-responsive element by arachidonic acid

1 reference

12 December 2020

1 reference

12 December 2020

Identifiers

DOI

10.1186/1478-1336-5-1

1 reference

Dimensions Publication ID

10 August 2017

0 references

1 reference

10 August 2017

1 reference