Transforming growth factor-beta2 is involved in quantitative genetic variation in thymic involution (Q35849450)

10 August 2017

Transforming growth factor-beta2 is involved in quantitative genetic variation in thymic involution (English)

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10 August 2017

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Ritu Kumar

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10 August 2017

Jessica C Langer

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2

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10 August 2017

Hans-Willem Snoeck

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3

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10 August 2017

language of work or name

English

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publication date

10 November 2005

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10 August 2017

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10 August 2017

107

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5

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10 August 2017

1974-1979

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describes a project that uses

10 August 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC1895709/fullTextXML

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Reduction in the developmental potential of intrathymic T cell progenitors with age

11 July 2018

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Is thymus redundant after adulthood?

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Myeloid-biased hematopoietic stem cells have extensive self-renewal capacity but generate diminished lymphoid progeny with impaired IL-7 responsiveness

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11 July 2018

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Quantitative trait analysis reveals transforming growth factor-beta2 as a positive regulator of early hematopoietic progenitor and stem cell function

11 July 2018

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11 July 2018

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11 July 2018

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TGFbeta2 knockout mice have multiple developmental defects that are non-overlapping with other TGFbeta knockout phenotypes

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Sex hormones as negative regulators of lymphopoiesis

11 July 2018

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11 July 2018

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Pgp-1hi T lymphocytes accumulate with age in mice and respond poorly to concanavalin A.

11 July 2018

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IL-7 gene therapy in aging restores early thymopoiesis without reversing involution

11 July 2018

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The positive regulatory effect of TGF-beta2 on primitive murine hemopoietic stem and progenitor cells is dependent on age, genetic background, and serum factors

24 September 2018

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Quantitative genetic variation in the hematopoietic stem cell and progenitor cell compartment and in lifespan are closely linked at multiple loci in BXD recombinant inbred mice

24 September 2018

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IL-12 inhibits thymic involution by enhancing IL-7- and IL-2-induced thymocyte proliferation

24 September 2018

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24 September 2018

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Deterministic regulation of hematopoietic stem cell self-renewal and differentiation.

24 September 2018

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Genetically determined variation in the number of phenotypically defined hematopoietic progenitor and stem cells and in their response to early-acting cytokines

24 September 2018

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CD4 memory T cell levels predict life span in genetically heterogeneous mice.

24 September 2018

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The pattern of T lymphocyte differentiation is altered during thymic involution

24 September 2018

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A developmental pathway involving four phenotypically and functionally distinct subsets of CD3-CD4-CD8- triple-negative adult mouse thymocytes defined by CD44 and CD25 expression.

24 September 2018

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Thymic function in young/old chimeras: substantial thymic T cell regenerative capacity despite irreversible age-associated thymic involution

24 September 2018

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12 December 2020

Age-associated thymic atrophy is linked to a decline in IL-7 production

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12 December 2020

Thymopoiesis independent of common lymphoid progenitors

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12 December 2020

Heterogeneity among DN1 prothymocytes reveals multiple progenitors with different capacities to generate T cell and non-T cell lineages

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12 December 2020

Hypertrophy of the thymus and restoration of immune functions in mice and rats by gonadectomy

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12 December 2020

10.1182/BLOOD-2005-04-1495

Identifiers

DOI

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10 August 2017

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10 August 2017

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