Insights into Autoregulation of Notch3 from Structural and Functional Studies of Its Negative Regulatory Region (Q35836383)

10 August 2017

Insights into Autoregulation of Notch3 from Structural and Functional Studies of Its Negative Regulatory Region (English)

1 reference

identical protein binding

10 August 2017

1 reference

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

Xiang Xu

1

1 reference

10 August 2017

Sung Hee Choi

2

1 reference

10 August 2017

Tiancen Hu

3

1 reference

10 August 2017

Kittichoat Tiyanont

4

1 reference

10 August 2017

Roger Habets

5

1 reference

10 August 2017

Arjan J Groot

6

1 reference

10 August 2017

Marc Vooijs

7

1 reference

10 August 2017

Jon C Aster

8

1 reference

10 August 2017

Rajiv Chopra

9

1 reference

10 August 2017

Christy Fryer

10

1 reference

10 August 2017

Stephen C Blacklow

11

1 reference

10 August 2017

4 June 2015

1 reference

10 August 2017

1 reference

10 August 2017

23

1 reference

10 August 2017

7

1 reference

10 August 2017

1227-1235

1 reference

Regulated proteolysis of NOTCH2 and NOTCH3 receptors by ADAM10 and presenilins

10 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4497832

Intrinsic selectivity of Notch 1 for Delta-like 4 over Delta-like 1.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4497832

Mutations in PDGFRB cause autosomal-dominant infantile myofibromatosis

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4497832

Linking Crystallographic Model and Data Quality

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4497832

Mapping the Deltex-binding surface on the notch ankyrin domain using analytical ultracentrifugation

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4497832

Integrated genomic analyses of ovarian carcinoma

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4497832

Notch signalling in T-cell lymphoblastic leukaemia/lymphoma and other haematological malignancies

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4497832

ConSurf 2010: calculating evolutionary conservation in sequence and structure of proteins and nucleic acids

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4497832

Therapeutic antibody targeting of individual Notch receptors

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4497832

PHENIX: a comprehensive Python-based system for macromolecular structure solution

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4497832

The canonical Notch signaling pathway: unfolding the activation mechanism

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4497832

Structure of the Notch1-negative regulatory region: implications for normal activation and pathogenic signaling in T-ALL

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4497832

Activating NOTCH3 mutation in a patient with small-vessel-disease of the brain

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4497832

Structural basis for autoinhibition of Notch

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4497832

DSL ligand endocytosis physically dissociates Notch1 heterodimers before activating proteolysis can occur

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4497832

Cooperative assembly of higher-order Notch complexes functions as a switch to induce transcription

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4497832

Notch3 gene amplification in ovarian cancer

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4497832

Leukemia-associated mutations within the NOTCH1 heterodimerization domain fall into at least two distinct mechanistic classes

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4497832

Structural basis for cooperativity in recruitment of MAML coactivators to Notch transcription complexes

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4497832

The adhesion force of Notch with Delta and the rate of Notch signaling

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4497832

Coot: model-building tools for molecular graphics

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4497832

Notch3 is required for arterial identity and maturation of vascular smooth muscle cells

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4497832

Notch subunit heterodimerization and prevention of ligand-independent proteolytic activation depend, respectively, on a novel domain and the LNR repeats

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4497832

Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4497832

Notch signaling and inherited disease syndromes

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4497832

Structure and function in rhodopsin: high-level expression of rhodopsin with restricted and homogeneous N-glycosylation by a tetracycline-inducible N-acetylglucosaminyltransferase I-negative HEK293S stable mammalian cell line

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4497832

A novel proteolytic cleavage involved in Notch signaling: the role of the disintegrin-metalloprotease TACE

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4497832

Roles of the ankyrin repeats and C-terminal region of the mouse notch1 intracellular region

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4497832

The Notch1 receptor is cleaved constitutively by a furin-like convertase

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4497832

Isolation and functional analysis of a cDNA for human Jagged2, a gene encoding a ligand for the Notch1 receptor

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4497832

Notch3 mutations in CADASIL, a hereditary adult-onset condition causing stroke and dementia

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4497832

Gamma-secretase inhibitor prevents Notch3 activation and reduces proliferation in human lung cancers.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4497832

The Notch amino terminus regulates protein levels and Delta-induced clustering of Drosophila Notch receptors.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4497832

A ligand-induced extracellular cleavage regulates gamma-secretase-like proteolytic activation of Notch1

24 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26051713

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Modulation of Notch signaling by antibodies specific for the extracellular negative regulatory region of NOTCH3

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26051713

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Processing of X-ray diffraction data collected in oscillation mode

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26051713

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.STR.2015.05.001

1 reference

10 August 2017

1 reference

10 August 2017

1 reference