Determinants of the elimination of methotrexate and 7-hydroxy-methotrexate following high-dose infusional therapy to cancer patients. (Q35827596)

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27 December 2019

title

Determinants of the elimination of methotrexate and 7-hydroxy-methotrexate following high-dose infusional therapy to cancer patients (English)

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27 December 2019

1 reference

Desiree van den Bongard

3

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27 December 2019

7

J H Beijnen

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27 December 2019

author name string

M Joerger

1

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27 December 2019

A D R Huitema

2

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27 December 2019

P Baas

4

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27 December 2019

J H Schornagel

5

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27 December 2019

J H M Schellens

6

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27 December 2019

language of work or name

English

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publication date

1 July 2006

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British Journal of Clinical Pharmacology

27 December 2019

published in

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27 December 2019

volume

62

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27 December 2019

issue

1

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27 December 2019

page(s)

71-80

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Mechanism of the pharmacokinetic interaction between methotrexate and benzimidazoles: potential role for breast cancer resistance protein in clinical drug-drug interactions

27 December 2019

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Sulfasalazine is a potent inhibitor of the reduced folate carrier: implications for combination therapies with methotrexate in rheumatoid arthritis

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Drug points: Severe myalgia from an interaction between treatments with pantoprazole and methotrexate

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27 July 2018

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27 July 2018

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Acute renal failure due to concomitant action of methotrexate and indomethacin

27 July 2018

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Clinical and pharmacokinetic evidence of a life-threatening interaction between methotrexate and ketoprofen

27 July 2018

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Use of Plasma Pharmacokinetics to Predict and Prevent Methotrexate Toxicity

27 July 2018

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Population pharmacokinetics of adjuvant cyclophosphamide, methotrexate and 5-fluorouracil (CMF).

27 July 2018

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Characterization of methotrexate transport and its drug interactions with human organic anion transporters

21 January 2018

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High-dose methotrexate: a clinical and pharmacokinetic evaluation. Treatment of advanced squamous cell carcinoma of the head and neck using a prospective mathematical model and pharmacokinetic surveillance.

21 January 2018

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High-dose methotrexate-induced nephrotoxicity in patients with osteosarcoma

21 January 2018

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Successful rescue with leucovorin and thymidine in a patient with high-dose methotrexate induced acute renal failure

21 January 2018

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Methotrexate disposition following concomitant administration of ketoprofen, piroxicam and flurbiprofen in patients with rheumatoid arthritis

21 January 2018

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A mutation in the drug transporter gene ABCC2 associated with impaired methotrexate elimination

21 January 2018

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Wild-type breast cancer resistance protein (BCRP/ABCG2) is a methotrexate polyglutamate transporter

24 September 2018

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Methotrexate and 7-hydroxy-methotrexate pharmacokinetics following intravenous bolus administration and high-dose infusion of methotrexate

24 September 2018

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12 December 2020

Pharmacokinetic interactions with methotrexate: is 7-hydroxy-methotrexate the culprit?

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12 December 2020

Stable and sensitive method for the simultaneous determination of N5-methyltetrahydrofolate, leucovorin, methotrexate and 7-hydroxymethotrexate in biological fluids

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12 December 2020

Pharmacokinetics of methotrexate and 7-hydroxy-methotrexate after high-dose (33.6 g/m2) methotrexate therapy

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Interaction between trimethoprim-sulfamethoxazole and methotrexate in children with leukemia

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12 December 2020

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12 December 2020

Interaction of chemotherapeutic agents with methotrexate and 5-fluorouracil and its effect on de novo DNA synthesis

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12 December 2020

The role of 7-hydroxymethotrexate during methotrexate anti-cancer therapy

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12 December 2020

Pharmacokinetics of methotrexate and 7-hydroxymethotrexate following infusions of high-dose methotrexate

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12 December 2020

The pharmacokinetics of 7-hydroxymethotrexate following medium-dose methotrexate therapy

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12 December 2020

Kinetics of 7-hydroxy-methotrexate after high-dose methotrexate therapy

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12 December 2020

Impact of omeprazole on the plasma clearance of methotrexate

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12 December 2020

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12 December 2020

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Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16842380%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

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27 December 2019

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