An evaluation of potential mechanism-based inactivation of human drug metabolizing cytochromes P450 by monoamine oxidase inhibitors, including isoniazid. (Q35827548)

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scientific article published in May 2006

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English	An evaluation of potential mechanism-based inactivation of human drug metabolizing cytochromes P450 by monoamine oxidase inhibitors, including isoniazid.	scientific article published in May 2006

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scholarly article

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16669850%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

An evaluation of potential mechanism-based inactivation of human drug metabolizing cytochromes P450 by monoamine oxidase inhibitors, including isoniazid (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16669850%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

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Elizabeth M. Gillam

4

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20 January 2020

Benjamin C Lewis

5

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20 January 2020

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Thomas M Polasek

1

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20 January 2020

David J Elliot

2

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20 January 2020

Andrew A Somogyi

3

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20 January 2020

John O Miners

6

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20 January 2020

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1 May 2006

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20 January 2020

British Journal of Clinical Pharmacology

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20 January 2020

61

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20 January 2020

5

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20 January 2020

570-584

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20 January 2020

In vitro-in vivo extrapolation of CYP2D6 inactivation by paroxetine: prediction of nonstationary pharmacokinetics and drug interaction magnitude

1 reference

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11 July 2018

CYP2B6, CYP3A4, and CYP2C19 are responsible for the in vitro N-demethylation of meperidine in human liver microsomes

1 reference

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Clinical pharmacology of MAO inhibitors: safety and future

1 reference

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11 July 2018

Mechanism-based inhibition of human liver microsomal cytochrome P450 1A2 by zileuton, a 5-lipoxygenase inhibitor

1 reference

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11 July 2018

Isoniazid is a mechanism-based inhibitor of cytochrome P450 1A2, 2A6, 2C19 and 3A4 isoforms in human liver microsomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885050

11 July 2018

Inhibition of cytochrome P450 (CYP450) isoforms by isoniazid: potent inhibition of CYP2C19 and CYP3A

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885050

11 July 2018

An in vitro model for predicting in vivo inhibition of cytochrome P450 3A4 by metabolic intermediate complex formation.

1 reference

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11 July 2018

Phenytoin metabolism by human cytochrome P450: involvement of P450 3A and 2C forms in secondary metabolism and drug-protein adduct formation.

1 reference

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11 July 2018

Selegiline metabolism and cytochrome P450 enzymes: in vitro study in human liver microsomes

1 reference

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11 July 2018

CYP3A4 drug interactions: correlation of 10 in vitro probe substrates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885050

11 July 2018

Metabolism of monoamine oxidase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885050

11 July 2018

Mechanism-based inactivation of human cytochrome P450 1A2 by furafylline: detection of a 1:1 adduct to protein and evidence for the formation of a novel imidazomethide intermediate

1 reference

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11 July 2018

Drug-mediated inactivation of cytochrome P450.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885050

11 July 2018

Inactivation of cytochrome P-450 and monoamine oxidase by cyclopropylamines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885050

11 July 2018

Differential effect of isoniazid on triazolam oxidation and oxazepam conjugation

1 reference

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11 July 2018

The in vitro inhibition of the N-demethylation of pethidine by phenelzine (Phenethylhydrazine).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885050

11 July 2018

New directions in monoamine oxidase A and B selective inhibitors and substrates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885050

11 July 2018

Pharmacokinetics of monoamine oxidase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885050

11 July 2018

Marked effect of liver and kidney function on the pharmacokinetics of selegiline

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2006.02627.X

21 January 2018

Isolation and characterization of an evolutionary precursor of human monoamine oxidases A and B.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2006.02627.X

21 January 2018

Mechanism-based inactivation of human cytochrome P4502C8 by drugs in vitro

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2006.02627.X

21 January 2018

Optimizing bacterial expression of catalytically active human cytochromes P450: comparison of CYP2C8 and CYP2C9.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2006.02627.X

21 January 2018

Drug metabolism by Escherichia coli expressing human cytochromes P450.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2006.02627.X

21 January 2018

Prediction of cytochrome P450 3A inhibition by verapamil enantiomers and their metabolites

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https://api.crossref.org/works/10.1111%2FJ.1365-2125.2006.02627.X

21 January 2018

Mechanism-based inactivation of CYP3A by HIV protease inhibitors

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https://api.crossref.org/works/10.1111%2FJ.1365-2125.2006.02627.X

21 January 2018

The influence of nonspecific microsomal binding on apparent intrinsic clearance, and its prediction from physicochemical properties.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2006.02627.X

21 January 2018

Dapsone activation of CYP2C9-mediated metabolism: evidence for activation of multiple substrates and a two-site model

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24 September 2018

Mechanism-based inactivation of CYP2D6 by 5-fluoro-2-[4-[(2-phenyl-1H-imidazol-5-yl)methyl]-1-piperazinyl]pyrimidine

1 reference

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Diazepam interaction with antituberculosis drugs.

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Moclobemide, a substrate of CYP2C19 and an inhibitor of CYP2C19, CYP2D6, and CYP1A2: A panel study*

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2006.02627.X

21 January 2018

Mechanism of the inhibitory action of isoniazid on microsomal drug metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/16669850

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of the inhibitory action of phenelzine on microsomal drug metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/16669850

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibitory effect of tranylcypromine on hepatic drug metabolism in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/16669850

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Free radical pathways in the in vitro hepatic metabolism of phenelzine

1 reference

https://pubmed.ncbi.nlm.nih.gov/16669850

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of cytochrome P-450-dependent oxidation reactions by MAO inhibitors in rat liver microsomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16669850

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Particular ability of cytochromes P450 3A to form inhibitory P450-iron-metabolite complexes upon metabolic oxidation of aminodrugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/16669850

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human hepatic cytochrome P450 2C9 catalyzes the rate-limiting pathway of torsemide metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/16669850

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isoniazid, tricyclics and the "cheese reaction"

1 reference

https://pubmed.ncbi.nlm.nih.gov/16669850

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inactivation of cytochrome P4502B1 by the monoamine oxidase inhibitors R-(-)-deprenyl and clorgyline

1 reference

https://pubmed.ncbi.nlm.nih.gov/16669850

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Formation of a metabolic intermediate complex of cytochrome P4502B1 by clorgyline

1 reference

https://pubmed.ncbi.nlm.nih.gov/16669850

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition and induction of cytochrome P450 and the clinical implications

1 reference

https://pubmed.ncbi.nlm.nih.gov/16669850

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1365-2125.2006.02627.X

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16669850%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16669850%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16669850%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

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